Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Alain Frigon"'
Publikováno v:
eLife, Vol 13 (2024)
Locomotion in mammals is directly controlled by the spinal neuronal network, operating under the control of supraspinal signals and somatosensory feedback that interact with each other. However, the functional architecture of the spinal locomotor net
Externí odkaz:
https://doaj.org/article/b8715281c81f40eca40cc23853622c71
Autor:
Stephen Mari, Charly G. Lecomte, Angèle N. Merlet, Johannie Audet, Jonathan Harnie, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
IntroductionDuring locomotion, cutaneous reflexes play an essential role in rapidly responding to an external perturbation, for example, to prevent a fall when the foot contacts an obstacle. In cats and humans, cutaneous reflexes involve all four lim
Externí odkaz:
https://doaj.org/article/cd622daf61dc41efa138139d29cf4b9b
Autor:
Jonathan Harnie, Johannie Audet, Stephen Mari, Charly G. Lecomte, Angèle N. Merlet, Gabriel Genois, Ilya A. Rybak, Boris I. Prilutsky, Alain Frigon
Publikováno v:
Frontiers in Systems Neuroscience, Vol 16 (2022)
Locomotion after complete spinal cord injury (spinal transection) in animal models is usually evaluated in a hindlimb-only condition with the forelimbs suspended or placed on a stationary platform and compared with quadrupedal locomotion in the intac
Externí odkaz:
https://doaj.org/article/926eb7dcd732405ab4c4bc1b1b2165be
Publikováno v:
Frontiers in Neuroinformatics, Vol 15 (2021)
Gait analysis in cats and other animals is generally performed with custom-made or commercially developed software to track reflective markers placed on bony landmarks. This often involves costly motion tracking systems. However, deep learning, and i
Externí odkaz:
https://doaj.org/article/1dc856e92e9644718d88b97b96baed0e
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Somatosensory feedback from peripheral receptors dynamically interacts with networks located in the spinal cord and brain to control mammalian locomotion. Although somatosensory feedback from the limbs plays a major role in regulating locomotor outpu
Externí odkaz:
https://doaj.org/article/667b592fe3a6485fb4be9c808c031cca
Autor:
Elizaveta M. Latash, Charly G. Lecomte, Simon M. Danner, Alain Frigon, Ilya A. Rybak, Yaroslav I. Molkov
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Rhythmic limb movements during locomotion are controlled by central pattern generator (CPG) circuits located in the spinal cord. It is considered that these circuits are composed of individual rhythm generators (RGs) for each limb interacting with ea
Externí odkaz:
https://doaj.org/article/37f5197d6f7547c49b28a2a2bd183db0
Autor:
Jonathan Harnie, Adam Doelman, Emmanuelle de Vette, Johannie Audet, Etienne Desrochers, Nathaly Gaudreault, Alain Frigon
Publikováno v:
eLife, Vol 8 (2019)
After complete spinal cord injury, mammals, including mice, rats and cats, recover hindlimb locomotion with treadmill training. The premise is that sensory cues consistent with locomotion reorganize spinal sensorimotor circuits. Here, we show that hi
Externí odkaz:
https://doaj.org/article/c5421c497e7e4e30aae26ae2229005ae
Autor:
Alain Frigon, Charly G. Lecomte
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 7, Pp 1919-1929 (2025)
Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate obstacles. After spinal cord injury, stepping over an obstacle becomes challenging. Stepping over an obstacle requires sensorimotor transformations in sev
Externí odkaz:
https://doaj.org/article/ced20f9bdf414beeaa3140cd54dc1718
Publikováno v:
eLife, Vol 6 (2017)
Interactions between cervical and lumbar spinal circuits are mediated by long propriospinal neurons (LPNs). Ablation of descending LPNs in mice disturbs left-right coordination at high speeds without affecting fore-hind alternation. We developed a co
Externí odkaz:
https://doaj.org/article/61706d2287924e1d95bfc2e18b2ea4f5
Autor:
Johannie, Audet, Jonathan, Harnie, Charly G, Lecomte, Stephen, Mari, Angèle N, Merlet, Boris I, Prilutsky, Ilya A, Rybak, Alain, Frigon
Publikováno v:
Journal of Neurotrauma. 39:1113-1131
Coordinating the four limbs is critical for terrestrial mammalian locomotion. Thoracic spinal transection abolishes neural communication between the brain and spinal networks controlling hindlimb/leg movements. Several studies have shown that animal