Proof of concept and development of a couple-based machine learning model to stratify infertile patients with idiopathic infertility

Autor: Guillaume, Bachelot, Rachel, Lévy, Anne, Bachelot, Céline, Faure, Sébastien, Czernichow, Charlotte, Dupont, Antonin, Lamazière, Alain, Favier

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.24003. ⟨10.1038/s41598-021-03165-3⟩
Scientific Reports, 2021, 11 (1), pp.24003. ⟨10.1038/s41598-021-03165-3⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

We aimed to develop and evaluate a machine learning model that can stratify infertile/fertile couples on the basis of their bioclinical signature helping the management of couples with unexplained infertility. Fertile and infertile couples were recru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd477cfd35b945f5e9e386afbc330de
https://hal.sorbonne-universite.fr/hal-03487156/file/s41598-021-03165-3.pdf

Effects of di(2-ethylhexyl)phthalate on testicular oxidant/antioxidant status in selenium-deficient and selenium-supplemented rats

Autor: Filiz Hincal, Isabelle Hininger-Favier, Walid Rachidi, Pinar Erkekoglu, Anne-Marie Roussel, Belma Giray, Alain Favier

Publikováno v: Environmental Toxicology. 29:98-107

Di(ethylhexyl)phthalate (DEHP), the most widely used plasticizer, was investigated to determine whether an oxidative stress process was one of the underlying mechanisms for its testicular toxicity potential. To evaluate the effects of selenium (Se),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::432bb0a791050ab338f3eb1493aa859c
https://doi.org/10.1002/tox.20776

Chromium III Histidinate Exposure Modulates Gene Expression in HaCaT Human Keratinocytes Exposed to Oxidative Stress

Autor: Mireille Osman, Isabelle Hininger-Favier, Kita Valenti, François Laporte, Anne-Marie Roussel, Richard A. Anderson, Florence Hazane-Puch, Rachida Benaraba, Alain Favier

Publikováno v: Biological Trace Element Research
Biological Trace Element Research, Humana Press, 2010, 137 (1), pp.23-39. ⟨10.1007/s12011-009-8557-9⟩

While the toxicity of hexavalent chromium is well established, trivalent chromium is an essential nutrient involved in insulin and glucose homeostasis. To study the antioxidant effects of Cr(III)His, cDNA arrays were used to investigate the modulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4986af9f6000408a01f3bd9db9ff7aa4
https://doi.org/10.1007/s12011-009-8557-9

Prion protein protects against zinc-mediated cytotoxicity by modifying intracellular exchangeable zinc and inducing metallothionein expression

Autor: Fabrice Chimienti, Michel Seve, Pascale Guiraud, M’hammed Aouffen, Alain Favier, Walid Rachidi, Abderrahmane Senator

Publikováno v: Journal of Trace Elements in Medicine and Biology. 23:214-223

PrPC contains several octapeptide repeats sequences toward the N-terminus which have binding affinity for divalent metals such as copper, zinc, nickel and manganese. However, the link between PrPC expression and zinc metabolism remains elusive. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c76458517939683a55181a2a9f0174
https://doi.org/10.1016/j.jtemb.2009.02.007

Plasma Carotenoids and Onset of Dysglycemia in an Elderly Population

Autor: Annick Fontbonne, Tasnime N. Akbaraly, Claudine Berr, Alain Favier

Publikováno v: Diabetes Care. 31:1355-1359

OBJECTIVE—The hypothesis of carotenoid having a preventive role in diabetes is suggested by their antioxidant properties. In this report, we investigated the relationship between baseline total plasma carotenoid levels and 9-year onset of dysglycem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f581d804b19f1ea0acee17f42039a04
https://doi.org/10.2337/dc07-2113