Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alain Dhainaut"'
Autor:
Jean-Pierre Bizzari, Alain Dhainaut, Nicolas Guilbaud, Maryse Berlion, Suzy Cros, Theresa A. Dunn, Ghanem Atassi, Gilbert Regnier
Publikováno v:
Cancer Chemotherapy and Pharmacology. 30:491-494
S 9788, a new triazinoaminopiperidine derivative, was found to be a potent reversant of vincristine resistance in the in vivo murine leukemic P388/VCR model. In two treatment regimens (Q4D days 1, 5 and 9 and QD days 1-9), S 9788 enhanced the antitum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f11aa90667d93c5e8222ccb744925c
https://doi.org/10.1007/bf00685604
https://doi.org/10.1007/bf00685604
Solid-Phase Parallel Synthesis: Optimization of Quinazolinedione Inhibitors of S-Farnesyltransferase
Autor:
Goulven Merer, Nathalie Kucharczyk, Andre Tizot, Alain Dhainaut, Gordon C. Tucker, Jean-Luc Fauchère, Solo Goldstein
Publikováno v:
ChemInform. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5cca8b9cb1c2df5eaa00eec01fb3463
https://doi.org/10.1002/chin.200748257
https://doi.org/10.1002/chin.200748257
Publikováno v:
ChemInform. 31
A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This conne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6fd3182f2c569c13fa382b825c6cb91
https://doi.org/10.1002/chin.200037128
https://doi.org/10.1002/chin.200037128
Publikováno v:
Journal of medicinal chemistry. 43(11)
A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This conne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeab99d24c5cd39f1208caa6937e73db
https://pubmed.ncbi.nlm.nih.gov/10841795
https://pubmed.ncbi.nlm.nih.gov/10841795
Autor:
Andre Tizot, Alain Dhainaut, Laurence Kraus-Berthier, Stéphane Léonce, Nicolas Guilbaud, Ghanem Atassi, Gilbert Regnier, Alain Pierré
Publikováno v:
Journal of medicinal chemistry. 39(20)
A series of 36 purine and purine analog derivatives have been synthesized and tested for their ability to modulate multidrug resistance in vitro (P388/VCR-20 and KB-A1 cells) and in vivo (P388/VCR leukemia). Compounds were compared to S9788, a triazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12c873412532e619326cf3cd06aef59
https://pubmed.ncbi.nlm.nih.gov/8831775
https://pubmed.ncbi.nlm.nih.gov/8831775
Autor:
D. Saint-Dizier, Ghanem Atassi, Stéphane Léonce, Jean-Pierre Bizzari, Alain Pierré, Laurence Kraus-Berthier, Gilbert Régnier, Theresa A. Dunn, Alain Dhainaut, Maryse Berlion
Publikováno v:
Investigational new drugs. 10(3)
S 9788 is a novel triazinoaminopiperidine derivative which does not belong to any of the classes of compounds known to reverse multidrug resistance (MDR). S 9788 was far more potent than verapamil (VRP) in reversing resistance to adriamycin (ADR) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc11e72c4fbaa84c91c7c2311f680b99
https://pubmed.ncbi.nlm.nih.gov/1428723
https://pubmed.ncbi.nlm.nih.gov/1428723
Autor:
Alain Dhainaut, Gilbert Regnier, Jean Francois Prost, Stéphane Léonce, Ghanem Atassi, Laurence Kraus-Berthier, Alain Pierré
Publikováno v:
Journal of medicinal chemistry. 35(13)
A series of 70 triazine derivatives have been synthesized and tested for their capacity to modulate multidrug resistance (MDR) in DC-3F/AD and KB-A1 tumor cells in vitro, in comparison with verapamil (VRP), a calcium channel antagonist currently used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25af248fb4b814f3d809332d77400cfc
https://pubmed.ncbi.nlm.nih.gov/1352353
https://pubmed.ncbi.nlm.nih.gov/1352353