Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alain Cosson"'
Autor:
Guilherme Dias de Melo, Nicolas Coatnoan, Nicolas Gouault, Jean-François Cupif, Jacques Renault, Alain Cosson, Philippe Uriac, Arnaud Blondel, Paola Minoprio
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 28, Iss , Pp 84-89 (2022)
ABSTRACT: Objectives: : Chagas disease, caused by the parasitic protozoan Trypanosoma cruzi, affects approximately 6–7 million people worldwide. There are limited available therapies and they exhibit low efficacy, often high toxicity in chronic cas
Externí odkaz:
https://doaj.org/article/a6c9dbb70f374d24ae6421255569de6f
Autor:
Patricia de Aguiar Amaral, Delphine Autheman, Guilherme Dias de Melo, Nicolas Gouault, Jean-François Cupif, Sophie Goyard, Patricia Dutra, Nicolas Coatnoan, Alain Cosson, Damien Monet, Frederick Saul, Ahmed Haouz, Philippe Uriac, Arnaud Blondel, Paola Minoprio
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006853 (2018)
Chagas disease, caused by Trypanosoma cruzi, affects millions of people in South America and no satisfactory therapy exists, especially for its life threatening chronic phase. We targeted the Proline Racemase of T. cruzi, which is present in all stag
Externí odkaz:
https://doaj.org/article/7b0e552c65c8459c810a1a47cf5be9fc
Autor:
Cher Pheng Ooi, Sarah Schuster, Christelle Cren-Travaillé, Eloïse Bertiaux, Alain Cosson, Sophie Goyard, Sylvie Perrot, Brice ROTUREAU
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Trypanosoma vivax is the most prevalent trypanosome species in African cattle. It is thought to be transmitted by tsetse flies after cyclical development restricted to the vector mouthparts. Here, we investigated the kinetics of T. vivax development
Externí odkaz:
https://doaj.org/article/5944f057a4fc4cd094a3e6e19e787483
Autor:
Leticia Coutinho, Marcelo Alves Ferreira, Alain Cosson, Marcos Meuser Batista, Denise da Gama Jaén Batista, Paola Minoprio, Wim M Degrave, Armand Berneman, Maria de Nazaré Correia Soeiro
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Iss 8, Pp 1055-1062 (2009)
Proline racemase is an important enzyme of Trypanosoma cruzi and has been shown to be an effective mitogen for B cells, thus contributing to the parasite's immune evasion and persistence in the human host. Recombinant epimastigote parasites overexpre
Externí odkaz:
https://doaj.org/article/ad21c48da2cb46b9a8da25b3b1314942
Autor:
Armand Berneman, Lory Montout, Sophie Goyard, Nathalie Chamond, Alain Cosson, Simon d'Archivio, Nicolas Gouault, Philippe Uriac, Arnaud Blondel, Paola Minoprio
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60955 (2013)
Chagas' disease is caused by Trypanosoma cruzi, a protozoan transmitted to humans by blood-feeding insects, blood transfusion or congenitally. Previous research led us to discover a parasite proline racemase (TcPRAC) and to establish its validity as
Externí odkaz:
https://doaj.org/article/f1a53129aa5947b39770b326a747a493
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 1, p e1976 (2013)
Trypanosoma vivax, one of the leading parasites responsible for Animal African Trypanosomosis (Nagana), is generally cyclically transmitted by Glossina spp. but in areas devoid of the tsetse flies in Africa or in Latin American countries is mechanica
Externí odkaz:
https://doaj.org/article/77bbb25aa43e4e90a2948a8abdc41192
Autor:
Simon D'Archivio, Mathieu Medina, Alain Cosson, Nathalie Chamond, Brice Rotureau, Paola Minoprio, Sophie Goyard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1461 (2011)
Trypanosoma vivax is one of the most common parasites responsible for animal trypanosomosis, and although this disease is widespread in Africa and Latin America, very few studies have been conducted on the parasite's biology. This is in part due to t
Externí odkaz:
https://doaj.org/article/074eb98a21c34660ab09e56aa35cbd4c
Autor:
Nathalie Chamond, Alain Cosson, Marie Christine Blom-Potar, Grégory Jouvion, Simon D'Archivio, Mathieu Medina, Sabrina Droin-Bergère, Michel Huerre, Sophie Goyard, Paola Minoprio
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 8, p e792 (2010)
African trypanosomiasis is a severe parasitic disease that affects both humans and livestock. Several different species may cause animal trypanosomosis and although Trypanosoma vivax (sub-genus Duttonella) is currently responsible for the vast majori
Externí odkaz:
https://doaj.org/article/79f6d12ff3ec46cfa7612ae520074c8e
Autor:
Marie Christine Blom-Potar, Nathalie Chamond, Alain Cosson, Grégory Jouvion, Sabrina Droin-Bergère, Michel Huerre, Paola Minoprio
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 8, p e793 (2010)
Trypanosoma vivax is the main species involved in trypanosomosis, but very little is known about the immunobiology of the infective process caused by this parasite. Recently we undertook to further characterize the main parasitological, haematologica
Externí odkaz:
https://doaj.org/article/8d73ee45647f4635bf1d4edd61eb7667
Autor:
Maira Goytia, Nathalie Chamond, Alain Cosson, Nicolas Coatnoan, Daniel Hermant, Armand Berneman, Paola Minoprio
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e885 (2007)
The first eukaryotic proline racemase (PRAC), isolated from the human Trypanosoma cruzi pathogen, is a validated therapeutic target against Chagas' disease. This essential enzyme is implicated in parasite life cycle and infectivity and its ability to
Externí odkaz:
https://doaj.org/article/c19bed3528174ca484e3312bad9063cd