Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alain Bourgois"'
Autor:
Sandrine Henri, Laurent Argiro, Bourema Kouriba, Hélia Dessein, Alain Dessein, Alain Bourgois
Publikováno v:
Vaccine. 18:2033-2038
Studies of anti-S. mansoni immunological responses in individuals living in endemic areas identified immunogens (Sm37-GAPDH and Sm10-DLC) with vaccine candidate properties. Analysis of the epitopes of these immunogens indicated that: (i) Sm37-5 is a
Autor:
Sibylle Kohlstädt, Hélia Dessein, Alain Dessein, Alain Bourgois, Laurent Argiro, Sandrine Henri, Patricia Paris, Véronique Matabiau
Publikováno v:
Vaccine. 18:2039-2048
A previous study performed in adolescents living in an area endemic for Schistosoma mansoni in Brazil has shown that a 37 kDa schistosome surface antigen is a selective target for antibodies in sera from those who were resistant to reinfection. This
Publikováno v:
Vaccine. 17:13-18
A previous study has shown that Sm37-5 is a major B cell epitope of Sm37-GAPDH. This epitope is highly antigenic in human infections and IgG antibody reactivity toward this determinant is associated with adolescent resistance to reinfection. This led
Publikováno v:
Parasitology International. 47:261-268
Sm10-DLC, a 10-kDa dynein light chain protein identified as a strong T cell immunogen in a large number of subjects sensitized by natural infections, may be of interest for vaccination. To assess the vaccine potential of Sm10 we carried out immunizat
Autor:
Patricia Couissinier-Paris, Hanno Kolbe, Alain Bourgois, Alain Dessein, Sybille Kohlstädt, Karen Piper, Bernadette Bouchon
Publikováno v:
Molecular and Biochemical Parasitology. 84:155-165
Parasite antigens that are strong T cell immunogens represent potential candidates for vaccines against pathogens susceptible to T cell-mediated immunity. We have previously shown that chromatographic fractions of schistosomula extracts contain compo
Autor:
Virmondes Rodrigues, Jérôme Pène, Patricia Couissinierhyphen, Sybille Kohlstädt, Hélia Dessein, Nathalie Buonavista, Olívia Bacellar, Paris, Alain Bourgois, Alain-Jacques Dessein
Publikováno v:
European Journal of Immunology. 25:903-910
Vaccine-induced immunity to Schistosoma mansoni infection depends on the specific priming of certain T cell subsets and on the recall of this response by natural infections months or years after vaccine administration. Thus, those schistosome protein
Autor:
Alain Bourgois, Monique Ouattara, Denise Carneiro-Carvalho, Laurent Abel, Alain Dessein, Pascal Rihet, Véronica Goudot-Crozel, Aluízio Prata, Edgar M. Carvallo, Christian Demeure, Patricia Couissinier, Hélia Dessein, Sibylle Kohlstaedt
Publikováno v:
Immunological Investigations. 21:423-453
The design of programs for the control of endemies requires the knowledge of the principal factors that determine parasite transmission and infection levels in exposed populations. In the studies summarized in this article, the role of environmental
Autor:
Alain Bourgois, Mamadou Ouattara, Christian Demeure, Laurent Abel, Alain Dessein, Pascal Rihet
Publikováno v:
The Journal of infectious diseases. 168(4)
The hypothesis of an association between human resistance to reinfection by the parasite Schistosoma mansoni and anti-larval immunoglobulin isotypes was tested by logistic regression in the presence of the explicative variables water contact, age, an
Publikováno v:
European journal of immunology. 22(8)
A method allowing the immunopurification of human IgE from small volumes of sera with a yield close to 100% (mean = 97.8%; SEM = 0.7) has been developed. The immunopurification eluates were cleared of other class antibodies that could compete with Ig
Publikováno v:
European journal of immunology. 21(11)
The anti-larval IgE antibody response of adolescents with high or low resistance to infection by Schistosoma mansoni was evaluated before parasitological cure with oxamniquine and over an extended post-treatment period during which the least resistan