Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alain Borczuk"'
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 14, Iss , Pp 100290- (2024)
Epithelioid angiosarcoma involving the lung is a rare entity that can present with nodules or consolidations on CT imaging. We describe the case of a 23-year-old woman who presented with chronic cough and pleuritic chest pain and consolidations on CT
Externí odkaz:
https://doaj.org/article/182b0d90567d44e8bcd64f1ddba2edd1
Autor:
Huijie Liu, Ayse Ece Cali Daylan, Jihua Yang, Ankit Tanwar, Alain Borczuk, Dongwei Zhang, Vincent Chau, Shenduo Li, Xuan Ge, Balazs Halmos, Xingxing Zang, Haiying Cheng
Publikováno v:
Cancers, Vol 16, Iss 16, p 2805 (2024)
Despite major advances in non-small-cell lung cancer (NSCLC) treatment, the five-year survival rates for patients with non-oncogene-driven tumors remain low, necessitating combinatory approaches to improve outcomes. Our prior high-throughput RNAi scr
Externí odkaz:
https://doaj.org/article/171dcf98dc8c488cbb0e8a8ff37d6498
Autor:
Feng Wang, Ayse Ece Cali Daylan, Lei Deng, Jihua Yang, Janaki Sharma, Christopher Su, Shenduo Li, Xingxing Zang, Balazs Halmos, Alain Borczuk, Haiying Cheng
Publikováno v:
Cancers, Vol 15, Iss 13, p 3372 (2023)
Immunotherapy has transformed lung cancer management, but PSC remains an aggressive subtype with a poor prognosis. This study investigates the differential expression of PD-L1 and alternative immune checkpoints (ICs; B7x, B7-H3, and HHLA2), and genet
Externí odkaz:
https://doaj.org/article/aca5c64cc23c416ab8f7a20ed50fd47b
Autor:
Luis G. Gómez-Escobar, Katherine L. Hoffman, Justin J. Choi, Alain Borczuk, Steven Salvatore, Sergio L. Alvarez-Mulett, Manuel D. Galvan, Zhen Zhao, Sabrina E. Racine-Brzostek, He S. Yang, Heather W. Stout-Delgado, Mary E. Choi, Augustine M. K. Choi, Soo Jung Cho, Edward J. Schenck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Increasing evidence has shown that Coronavirus disease 19 (COVID-19) severity is driven by a dysregulated immunologic response. We aimed to assess the differences in inflammatory cytokines in COVID-19 patients compared to contemporaneously h
Externí odkaz:
https://doaj.org/article/de6315cd729b4ccca1809ce8dcb1cf1d
Autor:
Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel Rosiene, Alon Shaiber, David Danko, Ebrahim Afshinnekoo, Matthew MacKay, Fritz J. Sedlazeck, Nikolay A. Ivanov, Maria Sierra, Diana Pohle, Michael Zietz, Undina Gisladottir, Vijendra Ramlall, Evan T. Sholle, Edward J. Schenck, Craig D. Westover, Ciaran Hassan, Krista Ryon, Benjamin Young, Chandrima Bhattacharya, Dianna L. Ng, Andrea C. Granados, Yale A. Santos, Venice Servellita, Scot Federman, Phyllis Ruggiero, Arkarachai Fungtammasan, Chen-Shan Chin, Nathaniel M. Pearson, Bradley W. Langhorst, Nathan A. Tanner, Youngmi Kim, Jason W. Reeves, Tyler D. Hether, Sarah E. Warren, Michael Bailey, Justyna Gawrys, Dmitry Meleshko, Dong Xu, Mara Couto-Rodriguez, Dorottya Nagy-Szakal, Joseph Barrows, Heather Wells, Niamh B. O’Hara, Jeffrey A. Rosenfeld, Ying Chen, Peter A. D. Steel, Amos J. Shemesh, Jenny Xiang, Jean Thierry-Mieg, Danielle Thierry-Mieg, Angelika Iftner, Daniela Bezdan, Elizabeth Sanchez, Thomas R. Campion, John Sipley, Lin Cong, Arryn Craney, Priya Velu, Ari M. Melnick, Sagi Shapira, Iman Hajirasouliha, Alain Borczuk, Thomas Iftner, Mirella Salvatore, Massimo Loda, Lars F. Westblade, Melissa Cushing, Shixiu Wu, Shawn Levy, Charles Chiu, Robert E. Schwartz, Nicholas Tatonetti, Hanna Rennert, Marcin Imielinski, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Here, using clinical samples and autopsy tissues, the authors combine fast-colorimetric test (LAMP) for SARS-CoV-2 infection and large-scale shotgun metatranscriptomics for host, viral, and microbial profiling and provide a map of the viral genetic f
Externí odkaz:
https://doaj.org/article/e049d27579f84e2b9f12b7b11bc7c436
Autor:
Oisin F. McElvaney, Takanori Asakura, Suzanne L. Meinig, Jose L. Torres-Castillo, Robert S. Hagan, Claudie Gabillard, Mark P. Murphy, Leigh B. Thorne, Alain Borczuk, Emer P. Reeves, Ross E. Zumwalt, Yu Mikami, Tomas P. Carroll, Kenichi Okuda, Grace Hogan, Oliver J. McElvaney, Jennifer Clarke, Natalie L. McEvoy, Patrick W. Mallon, Cormac McCarthy, Ger Curley, Matthew C. Wolfgang, Richard C. Boucher, Noel G. McElvaney
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103894- (2022)
Summary: Background: Interleukin-6 (IL-6) is elevated in SARS-CoV-2 infection. IL-6 regulates acute-phase proteins, such as alpha-1 antitrypsin (AAT), a key lung anti-protease. We investigated the protease-anti-protease balance in the circulation and
Externí odkaz:
https://doaj.org/article/8689f1b6c49645dc94c1c385411f7c38
Autor:
Yuji Kondo, Jason L. Larabee, Liang Gao, Huiping Shi, Bojing Shao, Christopher M. Hoover, J. Michael McDaniel, Yen-Chun Ho, Robert Silasi-Mansat, Stephanie A. Archer-Hartmann, Parastoo Azadi, R. Sathish Srinivasan, Alireza R. Rezaie, Alain Borczuk, Jeffrey C. Laurence, Florea Lupu, Jasimuddin Ahamed, Rodger P. McEver, James F. Papin, Zhongxin Yu, Lijun Xia
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a pandemic. Severe disease is associated with dysfunction of multiple organs, but some infected cells do not express ACE2, the canoni
Externí odkaz:
https://doaj.org/article/3801c57ff82e4a0eac422412dabc3d90
Autor:
Anupam Paliwal, Alexis M Temkin, Kristi Kerkel, Alexander Yale, Iveta Yotova, Natalia Drost, Simon Lax, Chia-Ling Nhan-Chang, Charles Powell, Alain Borczuk, Abraham Aviv, Ronald Wapner, Xiaowei Chen, Peter L Nagy, Nicholas Schork, Catherine Do, Ali Torkamani, Benjamin Tycko
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003622 (2013)
Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplot
Externí odkaz:
https://doaj.org/article/f0e4d8065da1497d94502a7a8f5e1683
Autor:
Ines Testoni, Anna Sapino, Erika Iacona, Alessia Montagner, Luca di Montegnacco, Laura Liberale, Alain Borczuk, Fiorella Calabrese
Publikováno v:
OBM Neurobiology. :1-9
During the first wave of the COVID-19 pandemic, pathologists had to follow new protocols in their work environment around the world to limit or prevent the possibility of transmission of the infection during the autopsy of infected corpses. By using
Autor:
Cheng, Feng Wang, Ayse Ece Cali Daylan, Lei Deng, Jihua Yang, Janaki Sharma, Christopher Su, Shenduo Li, Xingxing Zang, Balazs Halmos, Alain Borczuk, Haiying
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3372
Immunotherapy has transformed lung cancer management, but PSC remains an aggressive subtype with a poor prognosis. This study investigates the differential expression of PD-L1 and alternative immune checkpoints (ICs; B7x, B7-H3, and HHLA2), and genet