Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Alain Beschin"'
Autor:
Miriam Wöhner, Sarah Brechtelsbauer, Niklas Friedrich, Christof Vorsatz, Johanna Bulang, Chunguang Liang, Lena Schorr, Alain Beschin, Martin Guilliams, Jeffrey Ravetch, Falk Nimmerjahn, Markus Biburger
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113757- (2024)
Summary: Understanding the mechanisms underlying cytotoxic immunoglobulin G (IgG) activity is critical for improving therapeutic antibody activity and inhibiting autoantibody-mediated tissue pathology. While prior research highlights the important ro
Externí odkaz:
https://doaj.org/article/654bceaf63c342158e7b7f4bd4847ced
Autor:
Jean-François Hastir, Sandrine Delbauve, Lionel Larbanoix, Desislava Germanova, Cleo Goyvaerts, Justine Allard, Sophie Laurent, Karine Breckpot, Alain Beschin, Martin Guilliams, Véronique Flamand
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Partial hepatectomy (PH) is the main treatment for early-stage hepatocellular carcinoma (HCC). Yet, a significant number of patients undergo recursion of the disease that could be linked to the fate of innate immune cells during the liver regeneratio
Externí odkaz:
https://doaj.org/article/a8bc45aa64284bb8ba218c6bbc4775b3
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Infection of C57Bl/6 mice by pleomorphic African trypanosomes Trypanosoma brucei and T. congolense is characterized by parasitemia waves coupled with the production of systemic levels of TNF. This cytokine is known to control T. brucei growt
Externí odkaz:
https://doaj.org/article/9ccb1178e6e74b48a7a7e05f9c0d3d11
Autor:
Charlotte L. Scott, Fang Zheng, Patrick De Baetselier, Liesbet Martens, Yvan Saeys, Sofie De Prijck, Saskia Lippens, Chloé Abels, Steve Schoonooghe, Geert Raes, Nick Devoogdt, Bart N. Lambrecht, Alain Beschin, Martin Guilliams
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Tissue-resident macrophages are mostly derived from embryonic progenitors. Scott et al. develop a mouse model to specifically deplete Kupffer cells (KC) in vivoand show that monocyte-derived cells can repopulate KC niche and behave similar to their e
Externí odkaz:
https://doaj.org/article/fe465a1e14fb4c67be69745568b1a073
Autor:
Benoît Stijlemans, Lea Brys, Hannelie Korf, Pawel Bieniasz-Krzywiec, Amanda Sparkes, Liese Vansintjan, Lin Leng, Nele Vanbekbergen, Massimiliano Mazzone, Guy Caljon, Jan Van Den Abbeele, Steven Odongo, Carl De Trez, Stefan Magez, Jo A Van Ginderachter, Alain Beschin, Richard Bucala, Patrick De Baetselier
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005862 (2016)
Animal African trypanosomosis is a major threat to the economic development and human health in sub-Saharan Africa. Trypanosoma congolense infections represent the major constraint in livestock production, with anemia as the major pathogenic lethal f
Externí odkaz:
https://doaj.org/article/27d8fe7e50db487380b75545f7c124bf
Autor:
Benoit Stijlemans, Amanda Sparkes, Chloé Abels, Jiri Keirsse, Lea Brys, Yvon Elkrim, Patrick Baetselier, Alain Beschin, Jo Ginderachter
Publikováno v:
Bio-Protocol, Vol 5, Iss 10 (2015)
In homeostasis, the liver is critical for the metabolism of nutrients including sugars, lipids, proteins and iron, for the clearance of toxins, and to induce immune tolerance to gut-derived antigens. These functions predispose the liver to infection
Externí odkaz:
https://doaj.org/article/2d25a723fb274302aff3ebd034be7362
Autor:
Yannick Morias, Chloé Abels, Damya Laoui, Eva Van Overmeire, Martin Guilliams, Elio Schouppe, Frank Tacke, Carlie J deVries, Patrick De Baetselier, Alain Beschin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004873 (2015)
Monocytes consist of two well-defined subsets, the Ly6C+ and Ly6C- monocytes. Both CD11b+ myeloid cells populations have been proposed to infiltrate tissues during inflammation. While infiltration of Ly6C+ monocytes is an established pathogenic facto
Externí odkaz:
https://doaj.org/article/364b51ac1b5243528b50d1fa55f4e8c0
Autor:
Geert Raes, Wim Noël, Alain Beschin, Lea Brys, Patrick de Baetselier, Gh. Gholamreza Hassanzadeh
Publikováno v:
Clinical and Developmental Immunology, Vol 9, Iss 3, Pp 151-159 (2002)
Externí odkaz:
https://doaj.org/article/ec73aee0df8c4ffe97bfc0db1c1d8394
Autor:
Benoît Stijlemans, Lin Leng, Lea Brys, Amanda Sparkes, Liese Vansintjan, Guy Caljon, Geert Raes, Jan Van Den Abbeele, Jo A Van Ginderachter, Alain Beschin, Richard Bucala, Patrick De Baetselier
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004414 (2014)
African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type
Externí odkaz:
https://doaj.org/article/81e488ac59cc45378f6ef85f2ca1a656
Autor:
Géraldine De Muylder, Sylvie Daulouède, Laurence Lecordier, Pierrick Uzureau, Yannick Morias, Jan Van Den Abbeele, Guy Caljon, Michel Hérin, Philippe Holzmuller, Silla Semballa, Pierrette Courtois, Luc Vanhamme, Benoît Stijlemans, Patrick De Baetselier, Michael P Barrett, Jillian L Barlow, Andrew N J McKenzie, Luke Barron, Thomas A Wynn, Alain Beschin, Philippe Vincendeau, Etienne Pays
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003731 (2013)
In order to promote infection, the blood-borne parasite Trypanosoma brucei releases factors that upregulate arginase expression and activity in myeloid cells.By screening a cDNA library of T. brucei with an antibody neutralizing the arginase-inducing
Externí odkaz:
https://doaj.org/article/511927836da54f7db78eab97bcc2f4c0