Výsledky vyhledávání - "Alain BUISSON"

Akademický článek

Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability

Autor: Mariana Ramos-Brossier, David Romeo-Guitart, Fabien Lanté, Valérie Boitez, François Mailliet, Soham Saha, Manon Rivagorda, Eleni Siopi, Ivan Nemazanyy, Christine Leroy, Stéphanie Moriceau, Sarah Beck-Cormier, Patrice Codogno, Alain Buisson, Laurent Beck, Gérard Friedlander, Franck Oury

Publikováno v: Cell Death and Disease, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract In recent years, primary familial brain calcification (PFBC), a rare neurological disease characterized by a wide spectrum of cognitive disorders, has been associated to mutations in the sodium (Na)-Phosphate (Pi) co-transporter SLC20A2. How

Externí odkaz: https://doaj.org/article/72e96d92ec03461d8acc5a19f2ed7abf

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Akademický článek

Long term worsening of amyloid pathology, cerebral function, and cognition after a single inoculation of beta-amyloid seeds with Osaka mutation

Autor: Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain

Publikováno v: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)

Abstract Alzheimer’s disease (AD) is characterized by intracerebral deposition of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These peptides and proteins induce synaptic dysfunctions that are strongly correl

Externí odkaz: https://doaj.org/article/8307e6636dd947a5bdd092741308d2d4

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Akademický článek

Diversity of plant parasitic nematodes characterized from fields of the French national monitoring programme for the Columbia root-knot nematode

Autor: Nathan Garcia, Eric Grenier, Alain Buisson, Laurent Folcher

Publikováno v: PLoS ONE, Vol 17, Iss 3 (2022)

Plant parasitic nematodes are highly abundant in all agrosystems and some species can have a major impact on crop yields. To avoid the use of chemical agents and to find alternative methods to manage these pests, research studies have mainly focused

Externí odkaz: https://doaj.org/article/43ad2f2c15434ab7b65abb2a7fe4bb25

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Akademický článek

Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

Autor: Sylvie Gory-Fauré, Rebecca Powell, Julie Jonckheere, Fabien Lanté, Eric Denarier, Leticia Peris, Chi Hung Nguyen, Alain Buisson, Laurence Lafanechère, Annie Andrieux

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

The search for effective treatments for neuropsychiatric disorders is ongoing, with progress being made as brain structure and neuronal function become clearer. The central roles played by microtubules (MT) and actin in synaptic transmission and plas

Externí odkaz: https://doaj.org/article/c1a192c89d934d5a9b191202b317f1b4

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Akademický článek

A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Microtubule-associated protein 6 (MAP6) is known to be important for synaptic plasticity and cognition, supposedly via interaction with microtubules. Here, the authors found that MAP6 is crucial for the stabilisation of enlarged synapses through its

Externí odkaz: https://doaj.org/article/9a70b96ea1e0471499f443604529b0ce

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Akademický článek

TRPA1 channels promote astrocytic Ca2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide

Autor: Anthony Bosson, Adrien Paumier, Sylvie Boisseau, Muriel Jacquier-Sarlin, Alain Buisson, Mireille Albrieux

Publikováno v: Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2017)

Abstract Background Excessive synaptic loss is thought to be one of the earliest events in Alzheimer’s disease (AD). However, the key mechanisms that maintain plasticity of synapses during adulthood or initiate synapse dysfunction in AD remain unkn

Externí odkaz: https://doaj.org/article/1edb37d4c4214414ae7b8264d162a0d1

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Long term worsening of Alzheimer pathology and clinical outcome by a single inoculation of mutated beta-amyloid seeds

Autor: Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain

Background Alzheimer’s disease (AD) is characterized by intracerebral accumulation of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These lesions induce synaptic dysfunctions that are strongly correlated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::180efee41becf67c645905e930eb6eb3
https://doi.org/10.21203/rs.3.rs-2334976/v1

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Treating early postnatal circuit defect delays Huntington’s disease onset and pathology in mice

Autor: Barbara Yael Braz, Doris Wennagel, Leslie Ratié, Diego Alves Rodrigues de Souza, Jean Christophe Deloulme, Emmanuel L. Barbier, Alain Buisson, Fabien Lanté, Sandrine Humbert

Publikováno v: Science
Science, 2022, 377 (6613), pp.eabq5011. ⟨10.1126/science.abq5011⟩

International audience; Recent evidence has shown that even mild mutations in the Huntingtin gene that are associated with late-onset Huntington’s disease (HD) disrupt various aspects of human neurodevelopment. To determine whether these seemingly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6147460666730e4b2585e2f311226c
https://doi.org/10.1126/science.abq5011

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