Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Alain Artola"'
Autor:
Jérémy Signoret-Genest, Maxime Barnet, François Gabrielli, Youssef Aissouni, Alain Artola, Radhouane Dallel, Myriam Antri, Philip Tovote, Lénaïc Monconduit
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Migraine is a disabling neurological disorder, characterized by recurrent headaches. During migraine attacks, individuals often experience sensory symptoms such as cutaneous allodynia which indicates the presence of central sensit
Externí odkaz:
https://doaj.org/article/7a8bade7442048f8856898f1c5fead1d
Autor:
Corinne El Khoueiry, Cristina Alba-Delgado, Myriam Antri, Maria Gutierrez-Mecinas, Andrew J. Todd, Alain Artola, Radhouane Dallel
Publikováno v:
Cells, Vol 11, Iss 8, p 1356 (2022)
Mechanical allodynia (pain to normally innocuous tactile stimuli) is a widespread symptom of inflammatory and neuropathic pain. Spinal or medullary dorsal horn (SDH or MDH) circuits mediating tactile sensation and pain need to interact in order to ev
Externí odkaz:
https://doaj.org/article/9af9cae2a5634251989ad7de05a50b48
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73022 (2013)
Several lines of evidence suggest that the hypothalamus is involved in trigeminal pain processing. However, the organization of descending hypothalamic projections to the spinal trigeminal nucleus caudalis (Sp5C) remains poorly understood. Microinjec
Externí odkaz:
https://doaj.org/article/389c149e5d9241d49a752a0436ed268c
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
[This corrects the article on p. e73022 in vol. 8.].
Externí odkaz:
https://doaj.org/article/03da1e9b21074dfe9a26ec85712f1a41
Autor:
Corinne, El Khoueiry, Cristina, Alba-Delgado, Myriam, Antri, Maria, Gutierrez-Mecinas, Andrew J, Todd, Alain, Artola, Radhouane, Dallel
Publikováno v:
Cells. 11(8)
Mechanical allodynia (pain to normally innocuous tactile stimuli) is a widespread symptom of inflammatory and neuropathic pain. Spinal or medullary dorsal horn (SDH or MDH) circuits mediating tactile sensation and pain need to interact in order to ev
Publikováno v:
Journal of Neural Transmission
Journal of Neural Transmission, Springer Verlag, 2020, 127 (4), pp.527-540. ⟨10.1007/s00702-020-02162-6⟩
Journal of Neural Transmission, Springer Verlag, 2020, 127 (4), pp.527-540. ⟨10.1007/s00702-020-02162-6⟩
Chronic pain is a frequent and disabling condition that is significantly maintained by central sensitization, which results in pathological amplification of responses to noxious and innocuous stimuli. As such, mechanical allodynia, or pain in respons
Autor:
Myriam Antri, Alain Artola, Cristina Alba-Delgado, Lénaïc Monconduit, Radhouane Dallel, Sarah Mountadem, Noëmie Mermet-Joret
Publikováno v:
The Journal of Neuroscience. 38:10489-10504
Mechanical allodynia, a widespread pain symptom that still lacks effective therapy, is associated with the activation of a dorsally directed polysynaptic circuit within the spinal dorsal horn (SDH) or medullary dorsal horn (MDH), whereby tactile inpu
Autor:
Isabelle Abrunhosa-Thomas, Alexia Visseq, Radhouane Dallel, Fabrice Anizon, Francis Giraud, Amélie Descheemaeker, Alain Artola, Karine Hérault, Pascale Moreau
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩
European Journal of Medicinal Chemistry, Elsevier, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩
European Journal of Medicinal Chemistry, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩
European Journal of Medicinal Chemistry, Elsevier, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩
International audience; Mechanical allodynia, a painful sensation caused by innocuous touch, is a major chronic pain symptom, which often remains without an effective treatment. There is thus a need for new antiallodynic treatments based on new drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2264140f0508caa562f5b7e7f24c81fe
https://hal.science/hal-03334145/file/EurJMedChem-2021-113748.pdf
https://hal.science/hal-03334145/file/EurJMedChem-2021-113748.pdf
Autor:
Fabrice Anizon, Isabelle Abrunhosa-Thomas, Radhouane Dallel, Vincent Théry, Francis Giraud, Pascale Moreau, Lionel Nauton, Alexia Visseq, Nicolas Pinto-Pardo, Amélie Descheemaeker, Alain Artola
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 187, pp.111917. ⟨10.1016/j.ejmech.2019.111917⟩
European Journal of Medicinal Chemistry, 2020, 187, pp.111917. ⟨10.1016/j.ejmech.2019.111917⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 187, pp.111917. ⟨10.1016/j.ejmech.2019.111917⟩
European Journal of Medicinal Chemistry, 2020, 187, pp.111917. ⟨10.1016/j.ejmech.2019.111917⟩
Mechanical Allodynia (MA), a frequent chronic pain symptom caused by innocuous stimuli, constitutes an unmet medical need, as treatments using analgesics available today are not always effective and can be associated with important side-effects. A se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c04f243c9e7b9f6c47116987869cd9
https://hal.archives-ouvertes.fr/hal-02444268
https://hal.archives-ouvertes.fr/hal-02444268
Publikováno v:
European Journal of Neuroscience. 43:802-810
The γ isoform of protein kinase C (PKCγ), which is concentrated in a specific class of interneurons within inner lamina II (IIi ) of the spinal dorsal horn and medullary dorsal horn (MDH), is known to be involved in the development of mechanical al