Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Alain, Verreault"'
Autor:
Amogh Gopinathan Nair, Nick Rabas, Sara Lejon, Caleb Homiski, Michael J. Osborne, Normand Cyr, Aleksandr Sverzhinsky, Thomas Melendy, John M. Pascal, Ernest D. Laue, Katherine L. B. Borden, James G. Omichinski, Alain Verreault
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11099 (2022)
The eukaryotic DNA replication fork is a hub of enzymes that continuously act to synthesize DNA, propagate DNA methylation and other epigenetic marks, perform quality control, repair nascent DNA, and package this DNA into chromatin. Many of the enzym
Externí odkaz:
https://doaj.org/article/2e59bc152815426e9ca923121e0e3f23
Autor:
Alice Shi Ming Li, Charles Homsi, Eric Bonneil, Pierre Thibault, Alain Verreault, Masoud Vedadi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1866:194922
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a2bddb03d2c78c7d71ab7c342194d88
https://doi.org/10.1016/j.bbagrm.2023.194922
https://doi.org/10.1016/j.bbagrm.2023.194922
Publikováno v:
The FEBS Journal. 288:3478-3506
Candida albicans is a pathogenic fungus that causes systemic infections and mortality in immunosuppressed individuals. We previously showed that deacetylation of histone H3 lysine 56 by Hst3 is essential for C. albicans viability. Hst3 is a fungal-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eefd629afeacfb8d7906c04f769673c
https://doi.org/10.1111/febs.15622
https://doi.org/10.1111/febs.15622
Autor:
Juliana Andrea Pérez Di Giorgio, Audrey Loubert-Hudon, James G. Omichinski, Alain Verreault, Normand Brisson, Samuel Tremblay-Belzile
The identification of structural variations in genomes using next-generation sequencing approaches greatly facilitates the study of genetic and genomic diseases. The data generated using these approaches also provide interesting new means to examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6807ba2e513b51f66557ef49e4b1596
https://doi.org/10.1101/2020.03.06.980458
https://doi.org/10.1101/2020.03.06.980458
Autor:
Benoit Guillemette, Paul Drogaris, Hsiu-Hsu Sophia Lin, Harry Armstrong, Kyoko Hiragami-Hamada, Axel Imhof, Eric Bonneil, Pierre Thibault, Alain Verreault, Richard J Festenstein
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001354 (2011)
Methylation of histone H3 lysine 4 (H3K4me) is an evolutionarily conserved modification whose role in the regulation of gene expression has been extensively studied. In contrast, the function of H3K4 acetylation (H3K4ac) has received little attention
Externí odkaz:
https://doaj.org/article/b429b746debb42b39155c8db3261d43c
Autor:
Jennifer FitzGerald, Sylvie Moureau, Paul Drogaris, Enda O'Connell, Nebiyu Abshiru, Alain Verreault, Pierre Thibault, Muriel Grenon, Noel F Lowndes
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14714 (2011)
BackgroundDot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly defined.Methodology/principal findingsU
Externí odkaz:
https://doaj.org/article/88377b771a5243508fc14e3367b752f9
Publikováno v:
DNA Repair. 104:103140
A broad spectrum of spontaneous and genotoxin-induced DNA lesions impede replication fork progression. The DNA damage response that acts to promote completion of DNA replication is associated with dynamic changes in chromatin structure that include t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000708bf6c099e4f8ec5697338c8d0bb
https://doi.org/10.1016/j.dnarep.2021.103140
https://doi.org/10.1016/j.dnarep.2021.103140
Autor:
Jean-François Couture, Alain Verreault, Joseph S. Brunzelle, Anne-Claude Gingras, Jean-Philippe Lambert, Jacques Côté, Pierre Billon, Véronique Tremblay, Jian Li, Tomohiko Sugiyama, Yizhang Chen
Publikováno v:
Molecular Cell. 65:78-90
During DNA replication, proliferating cell nuclear antigen (PCNA) adopts a ring-shaped structure to promote processive DNA synthesis, acting as a sliding clamp for polymerases. Known posttranslational modifications function at the outer surface of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b11608969187600af2839d2e6398d1d
https://doi.org/10.1016/j.molcel.2016.10.033
https://doi.org/10.1016/j.molcel.2016.10.033
Autor:
Benoit Grondin, Trang Hoang, Marie-Claude Sincennes, Nazar Mashtalir, EL Bachir Affar, Magali Humbert, Alain Verreault, Christophe Cazaux, André Haman, Diogo F.T. Veiga, Véronique Lisi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Oncogenic transcription factors are commonly activated in acute leukemias and subvert normal gene expression networks to reprogram hematopoietic progenitors into preleukemic stem cells, as exemplified by LIM-only 2 (LMO2) in T-cell acute lymphoblasti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cae98a7bffc7963936d7754ab533a1
Autor:
Pierre Thibault, Zhiying You, Alain Verreault, Marlene Gharib, Krassimir Yankulov, Hisao Masai, Naoko Kakusho, Erin Drury, Daniel Jeffery, Brandon A. Wyse, Michael Weinreich
Publikováno v:
Cell Cycle. 14:74-85
Chromatin Assembly Factor I (CAF-I) plays a key role in the replication-coupled assembly of nucleosomes. It is expected that its function is linked to the regulation of the cell cycle, but little detail is available. Current models suggest that CAF-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c7a10a6b2cf9e29de4d09de2d1aa4d
https://doi.org/10.4161/15384101.2014.973745
https://doi.org/10.4161/15384101.2014.973745