Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Alain, Sarasin"'
Autor:
Leticia K. Lerner, Dorine Bonte, Morwenna Le Guillou, Mahwish Mian Mohammad, Zeinab Kasraian, Alain Sarasin, Emmanuelle Despras, Said Aoufouchi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/9d02092ecc5f4325948657a53eee289a
Autor:
Andrey. A. Yurchenko, Brice Fresneau, Bruno Borghese, Fatemeh Rajabi, Zora Tata, Catherine Genestie, Alain Sarasin, Sergey I. Nikolaev
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-8 (2023)
Abstract Background Xeroderma pigmentosum (XP) is a group of rare hereditary disorders with highly increased risk of skin tumors due to defective DNA repair. Recently we reported 34-fold increased risk of internal tumors in XP patients in comparison
Externí odkaz:
https://doaj.org/article/173eb58c3ebc4c67a77cceb3fa486a2a
Autor:
Andrey A. Yurchenko, Fatemeh Rajabi, Tirzah Braz-Petta, Hiva Fassihi, Alan Lehmann, Chikako Nishigori, Jinxin Wang, Ismael Padioleau, Konstantin Gunbin, Leonardo Panunzi, Fanny Morice-Picard, Pierre Laplante, Caroline Robert, Patricia L. Kannouche, Carlos F. M. Menck, Alain Sarasin, Sergey I. Nikolaev
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Xeroderma pigmentosum (XP) is a genetic disorder caused by mutations in genes of the Nucleotide Excision Repair (NER) pathway (groups A-G) or in Translesion Synthesis DNA polymerase η (V). XP is associated with an increased skin cancer risk
Externí odkaz:
https://doaj.org/article/43ea5e8dbf97496ea865d7ad15fce1e5
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Xeroderma pigmentosum (XP) is a rare, autosomal, recessive DNA repair-deficiency disorder with a frequency of 1–3 per million livebirths in Europe and USA but with higher frequencies in isolated islands or in countries with a hi
Externí odkaz:
https://doaj.org/article/382e0433cf2e44739c87a5359aee2590
Autor:
Michael Hamm, Pierre Sohier, Valérie Petit, Jérémy H. Raymond, Véronique Delmas, Madeleine Le Coz, Franck Gesbert, Colin Kenny, Zackie Aktary, Marie Pouteaux, Florian Rambow, Alain Sarasin, Nisamanee Charoenchon, Alfonso Bellacosa, Luis Sanchez-del-Campo, Laura Mosteo, Martin Lauss, Dies Meijer, Eirikur Steingrimsson, Göran B. Jönsson, Robert A. Cornell, Irwin Davidson, Colin R. Goding, Lionel Larue
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The transcription factor BRN2 regulates melanoma migration and invasion, but its role during melanoma initiation is unclear. Here the authors show that BRN2 is a haplo-insufficient tumour suppressor that positively regulates PTEN expression and in th
Externí odkaz:
https://doaj.org/article/963d00b98bc54a4ea97659da7f5bc553
Autor:
Leticia K. Lerner, Dorine Bonte, Morwenna Le Guillou, Mahwish Mian Mohammad, Zeinab Kasraian, Alain Sarasin, Emmanuelle Despras, Said Aoufouchi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Somatic hypermutation (SHM) of immunoglobulin (Ig) genes is a B cell specific process required for the generation of specific and high affinity antibodies during the maturation of the immune response against foreign antigens. This process depends on
Externí odkaz:
https://doaj.org/article/687ad53d7f674e85ab9e1d4e38391feb
Autor:
Andrey A. Yurchenko, Ismael Padioleau, Bakhyt T. Matkarimov, Jean Soulier, Alain Sarasin, Sergey Nikolaev
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Xeroderma Pigmentosum group C (XP-C) is a rare genetic disorder characterised by deficient DNA repair leading to skin and internal cancer, but the latter is not well understood molecularly. Here the authors sequence genomes of non-skin cancers from X
Externí odkaz:
https://doaj.org/article/486d5c1a2f994c9e87d502eb64b048d7
Autor:
Ligia Pereira Castro, Danilo Batista-Vieira, Tiago Antonio de Souza, Ana Rafaela de Souza Timoteo, Jessica Dayanna Landivar Coutinho, Isabel Cristina Pinheiro de Almeida, Sheila Ramos de Miranda Henriques, Fabio Medeiros de Azevedo, Reginaldo Cruz Alves Rosa, Patricia L Kannouche, Alain Sarasin, Carlos Frederico Martins Menck, Tirzah Braz Petta
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Xeroderma pigmentosum (XP) is a rare genetic condition in which exposure to sunlight leads to a high tumor incidence due to defective DNA repair machinery. Herein, we investigated seven patients clinically diagnosed with XP living in a small city, Mo
Externí odkaz:
https://doaj.org/article/f25b319a39694d058ff782d4ec67f61e
Publikováno v:
Genetics and Molecular Biology, Vol 43, Iss 1 suppl 1 (2019)
Abstract Xeroderma pigmentosum (XP) is a rare, genetic, autosomal nucleotide excision repair-deficient disease characterized by sun-sensitivity and early appearance of skin and ocular tumors. Thirty-two black-skinned XP from Comoros, located in the I
Externí odkaz:
https://doaj.org/article/bb997d3846654b2dbfac0948f44d8ee8
Autor:
Camila Corradi, Juliana B Vilar, Vanessa C Buzatto, Tiago A de Souza, Ligia P Castro, Veridiana Munford, Rodrigo De Vecchi, Pedro A F Galante, Fernanda Orpinelli, Thiago L A Miller, José L Buzzo, Mirian N Sotto, Paulo Saldiva, Jocelânio W de Oliveira, Sulamita C W Chaibub, Alain Sarasin, Carlos F M Menck
Publikováno v:
Carcinogenesis.
Xeroderma pigmentosum variant (XP-V) is an autosomal recessive disease with an increased risk of developing cutaneous neoplasms in sunlight-exposed regions. These cells are deficient in the translesion synthesis (TLS) DNA polymerase eta, responsible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8084142f94cb486a30e9ef839f389caf
https://doi.org/10.1093/carcin/bgad030
https://doi.org/10.1093/carcin/bgad030