Treatment patterns and outcomes among patients with small-cell lung cancer (SCLC) in Europe: a retrospective cohort study

Autor: Nuria Lara, Montserrat Roset, Fiona Blackhall, Nicolas Girard, Laura McDonald, Alain Livartowski, Ariadna Juarez García

Publikováno v: BMJ Open, Vol 13, Iss 2 (2023)

Objective Describe characteristics, treatment patterns and clinical outcomes of patients with small-cell lung cancer (SCLC).Design Retrospective chart review study defining several cohorts: (1) limited-stage disease (LD) SCLC initiating 1L therapy (1

Externí odkaz: https://doaj.org/article/9bb28ed16b424cbfb7efd814eaac5811

How to Improve Cancer Patients ENrollment in Clinical Trials From rEal-Life Databases Using the Observational Medical Outcomes Partnership Oncology Extension: Results of the PENELOPE Initiative in Urologic Cancers

Autor: Emmanuelle Kempf, Morgan Vaterkowski, Damien Leprovost, Nicolas Griffon, David Ouagne, Stéphane Breant, Patricia Serre, Alexandre Mouchet, Bastien Rance, Gilles Chatellier, Ali Bellamine, Marie Frank, Julien Guerin, Xavier Tannier, Alain Livartowski, Martin Hilka, Christel Daniel

Publikováno v: JCO Clinical Cancer Informatics
JCO Clinical Cancer Informatics, 2023, 7, ⟨10.1200/CCI.22.00179⟩

PURPOSE To compare the computability of Observational Medical Outcomes Partnership (OMOP)–based queries related to prescreening of patients using two versions of the OMOP common data model (CDM; v5.3 and v5.4) and to assess the performance of the G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec71e8d8193de6d2ea29d663665b5875
https://doi.org/10.1200/cci.22.00179

Greedy clustering of count data through a mixture of multinomial PCA

Autor: Nicolas Jouvin, Charles Bouveyron, Pierre Latouche, Alain Livartowski, Guillaume Bataillon

Publikováno v: Computational Statistics
Computational Statistics, Springer Verlag, In press, ⟨10.1007/s00180-020-01008-9⟩
Computational Statistics, In press, ⟨10.1007/s00180-020-01008-9⟩

Count data is becoming more and more ubiquitous in a wide range of applications, with datasets growing both in size and in dimension. In this context, an increasing amount of work is dedicated to the construction of statistical models directly accoun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2e9b93504fcb0d25b3d72ee03d85dc
https://doi.org/10.1007/s00180-020-01008-9

High

Autor: Elodie, Montaudon, Rania, El Botty, Sophie, Vacher, Olivier, Déas, Adnan, Naguez, Sophie, Chateau-Joubert, Damien, Treguer, Ludmilla, de Plater, Leïla, Zemoura, Fariba, Némati, André, Nicolas, Alain, Chapelier, Alain, Livartowski, Stefano, Cairo, Catherine, Daniel, Marie, Brevet, Elisabetta, Marangoni, Didier, Meseure, Sergio, Roman-Roman, Ivan, Bieche, Nicolas, Girard, Didier, Decaudin

Publikováno v: Oncotarget

Significant rational is available for specific targeting of PI3K/AKT/mTOR pathway in the treatment of non-small cell lung cancer (NSCLC). However, almost all clinical trials that have evaluated Pi3K pathway-based monotherapies/combinations did not ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d923927e729d329cdbab52c1300a9cb5
https://pubmed.ncbi.nlm.nih.gov/33889306

Collaborative federated learning behind hospitals’ firewalls for predicting histological complete response to neoadjuvant chemotherapy in triple-negative breast cancer

Autor: Jean Ogier du Terrail, Armand Leopold, Clément Joly, Mathieu Andreux, Charles Maussion, Benoit Schmauch, Mikhail Zaslavskiy, Gilles Wainrib, Maud Milder, Julie Gervasoni, Julien Guérin, Thierry Durand, Alain Livartowski, Kelvin Moutet, Clément Gautier, Anne-Laure Moisson, Camille Marini, Mathieu Galtier, Pierre Etienne Heudel, Guillaume Bataillon

Publikováno v: Journal of Clinical Oncology. 40:590-590

590 Background: Triple-Negative Breast Cancer (TNBC) is characterized by high metastatic potential and poor prognosis with limited treatment options. Neoadjuvant chemotherapy (NACT) is the standard of care in non-metastastic setting due to the abilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eecf094f7888d5aaf44a39e453cca7e0
https://doi.org/10.1200/jco.2022.40.16_suppl.590