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Akademický článek

Screening and toxicity evaluation of natural compounds as adenosine 2a and 2b receptor ligands: insights from molecular docking, dynamics, and ADMET analysis.

Autor: Karakuş F; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Türkiye., Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, İnönü University, Malatya, Türkiye., Kuzu B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Van Yuzuncu Yil University, Van, Türkiye.

Publikováno v: Drug and chemical toxicology [Drug Chem Toxicol] 2024 Aug 20, pp. 1-10. Date of Electronic Publication: 2024 Aug 20.

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Akademický článek

Investigation of inhibitory effect of sulfated chitosan oligomer on human heparanase enzyme: in silico and in vitro studies.

Autor: Kocabay S; Department of Molecular Biology and Genetics, Faculty of Science and Literature, Inonu University, Malatya, Türkiye., Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, Malatya, Türkiye., Akkaya B; Department of Molecular Biology and Genetics, Faculty of Science, Sivas Cumhuriyet University, Sivas, Türkiye.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Feb 27, pp. 1-9. Date of Electronic Publication: 2024 Feb 27.

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Akademický článek

Synthesis, characterization, evaluation of metabolic enzyme inhibitors and in silico studies of thymol based 2-amino thiol and sulfonic acid compounds.

Autor: Bora RE; Department of Chemistry, Faculty of Sciences, Erciyes University, 38039, Kayseri, Turkey. Electronic address: rifatbora@erciyes.edu.tr., Genc Bilgicli H; Department of Chemistry, Faculty of Sciences, Sakarya University, 54050, Sakarya, Turkey. Electronic address: hayriyegenc@sakarya.edu.tr., Üç EM; Department of Chemistry, Faculty of Sciences, Ataturk University, 25240, Erzurum, Turkey. Electronic address: edamehtap3@gmail.com., Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, İnonu University, 44280, Malatya, Turkey. Electronic address: mehmet.alagoz@inonu.edu.tr., Zengin M; Department of Chemistry, Faculty of Sciences, Sakarya University, 54050, Sakarya, Turkey. Electronic address: mzengin@sakarya.edu.tr., Gulcin İ; Department of Chemistry, Faculty of Sciences, Ataturk University, 25240, Erzurum, Turkey. Electronic address: igulcin@atauni.edu.tr.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2022 Oct 01; Vol. 366, pp. 110134. Date of Electronic Publication: 2022 Aug 31.

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Akademický článek

Antifungal Azole Derivatives Featuring Naphthalene Prove Potent and Competitive Cholinesterase Inhibitors with Potential CNS Penetration According to the in Vitro and in Silico Studies.

Autor: Sari S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey., Akkaya D; Department of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Turkey., Zengin M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey., Sabuncuoğlu S; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, 06100, Ankara, Turkey., Özdemir Z; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inönü University, 44280, Malatya, Turkey., Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inönü University, 44280, Malatya, Turkey., Karakurt A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inönü University, 44280, Malatya, Turkey., Barut B; Department of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Turkey.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2022 Jul; Vol. 19 (7), pp. e202200027. Date of Electronic Publication: 2022 Jun 23.

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Akademický článek

Histological assessment of liver and stomach damage caused by pyridazinone derivative antidepressant agents.

Autor: Özdemir Z; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, Malatya, Turkey., Karakurt A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, Malatya, Turkey., Taşlidere E; Department of Embryology and Histology, Faculty of Medicine, Inonu University, Malatya, Turkey., Vardi N; Department of Embryology and Histology, Faculty of Medicine, Inonu University, Malatya, Turkey., Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, Malatya, Turkey., Parlakpinar H; Department of Medical Pharmacology, Faculty of Medicine, Inonu University, Malatya, Turkey., Uslu H; Department of Anesthesiology, Vocational School of Health Services, Fırat University, Elazığ, Turkey., Bağ HG; Department of Biostatistics, Faculty of Medicine, Inonu University, Malatya, Turkey.

Publikováno v: Biotechnic & histochemistry : official publication of the Biological Stain Commission [Biotech Histochem] 2022 Jul; Vol. 97 (5), pp. 355-362. Date of Electronic Publication: 2021 Nov 29.

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Akademický článek

Development of a Novel Class of Pyridazinone Derivatives as Selective MAO-B Inhibitors.

Autor: Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280 Malatya, Turkey., Oh JM; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Korea., Zenni YN; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280 Malatya, Turkey., Özdemir Z; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inonu University, 44280 Malatya, Turkey., Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Al Jouf 72341, Saudi Arabia., Naguib IA; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia., Ghoneim MM; Department of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah 13713, Saudi Arabia., Gambacorta N; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', Via E. Orabona, 4, 70125 Bari, Italy., Nicolotti O; Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari 'Aldo Moro', Via E. Orabona, 4, 70125 Bari, Italy., Kim H; Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Korea., Mathew B; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 13; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 13.

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Akademický článek

Azoles containing naphthalene with activity against Gram-positive bacteria: in vitro studies and in silico predictions for flavohemoglobin inhibition.

Autor: Sari S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Sabuncuoğlu S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Koçak Aslan E; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Avci A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Kart D; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Özdemir Z; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inönü University, Malatya, Turkey., Acar MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Sayoğlu B; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey., Alagöz MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inönü University, Malatya, Turkey., Karakurt A; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Inönü University, Malatya, Turkey., Dalkara S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2022; Vol. 40 (20), pp. 10220-10229. Date of Electronic Publication: 2021 Jun 17.

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Akademický článek

Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2 H )-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.

Autor: Alagöz MA; İnönü University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 44280 Malatya, Turkey., Özdemir Z; İnönü University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 44280 Malatya, Turkey., Uysal M; Gazi University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06010 Ankara, Turkey., Carradori S; Department of Pharmacy, 'G. d'Annunzio' University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy., Gallorini M; Department of Pharmacy, 'G. d'Annunzio' University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy., Ricci A; Department of Pharmacy, 'G. d'Annunzio' University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy., Zara S; Department of Pharmacy, 'G. d'Annunzio' University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy., Mathew B; Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi 682 041, India.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2021 Feb 25; Vol. 14 (3). Date of Electronic Publication: 2021 Feb 25.

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