Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alabbas, Alkhatib"'
Autor:
Anila Vadakumchery, Hemin Faraidun, Omar El Ayoubi, Issame Outaleb, Vera Schmid, Hend Abdelrasoul, Timm Amendt, Ahmad Khadour, Corinna Setz, Katharina Göhring, Karoline Lodd, Christoffer Hitzing, Alabbas Alkhatib, Mayas Bilal, Julian Benckendorff, Abdul Kader Al Shugri, Cord Herbert Brakebusch, Niklas Engels, Moumita Datta, Elias Hobeika, Ameera Alsadeq, Hassan Jumaa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR. The adaptor protein SLP65 (also known as BLNK) is an important signaling fac
Externí odkaz:
https://doaj.org/article/bba221cfcb304def8ce9db2a80eaa6fd
Autor:
Claudia Minici, Maria Gounari, Rudolf Übelhart, Lydia Scarfò, Marcus Dühren-von Minden, Dunja Schneider, Alpaslan Tasdogan, Alabbas Alkhatib, Andreas Agathangelidis, Stavroula Ntoufa, Nicholas Chiorazzi, Hassan Jumaa, Kostas Stamatopoulos, Paolo Ghia, Massimo Degano
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Chronic lymphocytic leukaemia (CLL) is characterized by cell-autonomous B-cell receptor (BcR)-mediated signalling of neoplastic B lymphocytes. Here the authors unveil the structural basis and diversity of activatory homotypic BcR contacts and link th
Externí odkaz:
https://doaj.org/article/d134c066cc4e4ceb916cfd21f5f03500
Autor:
Eva Hug, Hassan Jumaa, Markus Werner, Sebastian Herzog, Thomas Wossning, Hemin Faraidun, Fabian Kohler, Cathrin Eschbach, Alabbas Alkhatib
Publikováno v:
The Journal of Experimental Medicine
During murine B cell development, PI3 kinase inhibits Ig gene rearrangement by suppressing FoxO1, which mediates Ikaros mRNA splicing; Ikaros is needed for Ig gene recombination.
Somatic rearrangement of immunoglobulin (Ig) genes is a key step d
Somatic rearrangement of immunoglobulin (Ig) genes is a key step d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef22df6b6ff76b8e50bed57d70c88401
https://doi.org/10.1084/jem.20110216
https://doi.org/10.1084/jem.20110216
Autor:
Isabel Wilhelm, Katja Zirlik, Hassan Jumaa, Winfried Römer, Marco Benkißer-Petersen, Cornelis A.M. van Bergen, Sergey Krysov, Graham Packham, Corinna S. Setz, Freda K. Stevenson, Sarah Villringer, Dunja Schneider, Hendrik Veelken, Alabbas Alkhatib, Christian Buske, Marcus Dühren-von Minden
Publikováno v:
Blood, 125(21), 3287-3296
B-cell antigen receptor (BCR) expression is a key feature of most B-cell lymphomas, but the mechanisms of BCR signal induction and the involvement of autoantigen recognition remain unclear. In follicular lymphoma (FL) B cells, BCR expression is retai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da802c743a9349793e538620e891bd8d
https://hdl.handle.net/1887/106582
https://hdl.handle.net/1887/106582
Autor:
Gounari, Maria *, Minici, Claudia *, Dühren-von Minden, Marcus *, Dunja, Schneider *, Alabbas, Alkhatib *, Rudolf, Übelhart *, Agathangelidis, Andreas *, Ntoufa, Stavroula *, Chiorazzi, Nicholas, Jumaa, Hassan *, Stamatopoulos, Kostas *, Degano, Massimo *, Ghia, Paolo *
Publikováno v:
In Blood 3 December 2015 126(23):4129-4129