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pro vyhledávání: '"Alaa Taha A. Mahdi"'
Autor:
Yong-Jie Xu, Sankhadip Bhadra, Alaa Taha A Mahdi, Kamal Dev, Ilknur Yurtsever, Toru M Nakamura
Publikováno v:
PLoS Genetics, Vol 19, Iss 5, p e1010691 (2023)
Replication protein A (RPA) is a heterotrimeric complex and the major single-strand DNA (ssDNA) binding protein in eukaryotes. It plays important roles in DNA replication, repair, recombination, telomere maintenance, and checkpoint signaling. Because
Externí odkaz:
https://doaj.org/article/f820d48660ac4b31823c8bd998e4ca66
Publikováno v:
Current Genetics. 67:369-382
DNA replication checkpoint is a cell signaling pathway that is activated in response to perturbed replication. Although it is crucial for maintaining genomic integrity and cell survival, the exact mechanism of the checkpoint signaling remains to be u