Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Alaa S Awad"'
Autor:
Mariana Murea, Jochen G. Raimann, Jasmin Divers, Harvey Maute, Cassandra Kovach, Emaad M. Abdel-Rahman, Alaa S. Awad, Jennifer E. Flythe, Samir C. Gautam, Vandana D. Niyyar, Glenda V. Roberts, Nichole M. Jefferson, Islam Shahidul, Ucheoma Nwaozuru, Kristie L. Foley, Erica J. Trembath, Merlo L. Rosales, Alison J. Fletcher, Sheikh I. Hiba, Anne Huml, Daphne H. Knicely, Irtiza Hasan, Bhaktidevi Makadia, Raman Gaurav, Janice Lea, Paul T. Conway, John T. Daugirdas, Peter Kotanko, on behalf of the Two Plus Research Consortium
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background Most patients starting chronic in-center hemodialysis (HD) receive conventional hemodialysis (CHD) with three sessions per week targeting specific biochemical clearance. Observational studies suggest that patients with residual ki
Externí odkaz:
https://doaj.org/article/cb69bbe49aa241258494659b3b8944fb
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133777 (2015)
Our recent publication showed that a small bioactive pigment epithelium derived factor (PEDF) peptide (P78-PEDF) prevents the development of diabetic nephropathy (DN). However, its effects on the progression of established DN were not clear. Therefor
Externí odkaz:
https://doaj.org/article/ad11a2b3174745c988c95fa11d2d0d3f
Publikováno v:
Journal of Engineering, Vol 30, Iss 9 (2024)
The study area, which consists of carbonate, is located in the unstable Mesopotamian basin on the Arabian plate, which makes it a field with high heterogeneity. It has a discrepancy in its bubble point pressure, which raises concerns about the faults
Externí odkaz:
https://doaj.org/article/7475b0488fa9449db563b3ec9ba37fc3
Autor:
Irtiza Hasan, Tasnuva Rashid, Vishal Jaikaransingh, Charles Heilig, Emaad M. Abdel-Rahman, Alaa S. Awad
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 35, Iss , Pp 100335- (2024)
Multiple randomized controlled trials have extensively examined the therapeutic effectiveness of sodium-glucose cotransporter 2 (SGLT2) inhibitors, ushering in a transformative approach to treating individuals with type 2 diabetes mellitus (DM). Nota
Externí odkaz:
https://doaj.org/article/6bd50762bd83469cbe7bc11b3fe0057b
Autor:
Michael D. Wetzel, Kristen Stanley, Soumya Maity, Muniswamy Madesh, Jean C. Bopassa, Alaa S. Awad
Publikováno v:
Physiological Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Recently we showed that homoarginine supplementation confers kidney protection in diabetic mouse models. In this study we tested whether the protective effect of homoarginine is nitric oxide synthase‐3 (NOS3)‐independent in diabetic neph
Externí odkaz:
https://doaj.org/article/f707223766d44a32a1abf424534cbdad
Autor:
Michael D. Wetzel, Kristen Stanley, Wei Wei Wang, Soumya Maity, Muniswamy Madesh, W. Brian Reeves, Alaa S. Awad
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Fibrosis is the final common pathway in the pathophysiology of most forms of chronic kidney disease (CKD). As treatment of renal fibrosis still remains largely supportive, a refined understanding of the cellular and molecular mechanisms of kidney fib
Externí odkaz:
https://doaj.org/article/483b48be22c64c11a53ed382f43916ae
Publikováno v:
Journal of clinical medicine. 12(1)
Acute kidney injury (AKI) is a common clinical syndrome characterized by a sudden decline in or loss of kidney function. AKI is not only associated with substantial morbidity and mortality but also with increased risk of chronic kidney disease (CKD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a37cffb84b72feade5243097c85e781
https://pubmed.ncbi.nlm.nih.gov/36615175
https://pubmed.ncbi.nlm.nih.gov/36615175
Publikováno v:
Journal of clinical medicine. 11(21)
Acute kidney injury (AKI) is a serious problem, affecting multiple organs, and is associated with a high mortality. The severe consequences of AKI extend beyond hospital discharge to the outpatient setting. While a plethora of literature exists guidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1818a5a79b631d34e1dd2922eb06c5a
https://pubmed.ncbi.nlm.nih.gov/36362503
https://pubmed.ncbi.nlm.nih.gov/36362503
Publikováno v:
Nature Reviews Nephrology. 17:319-334
Diabetic kidney disease is the leading cause of kidney failure worldwide; in the USA, it accounts for over 50% of individuals entering dialysis or transplant programmes. Unlike other complications of diabetes, the prevalence of diabetic kidney diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51a134f4a613ac68eb086b5de8e47aa7
https://doi.org/10.1038/s41581-021-00393-8
https://doi.org/10.1038/s41581-021-00393-8
Autor:
Kristen Stanley, Michael D. Wetzel, Ting Gao, Timothy K. Cooper, Alaa S. Awad, Sidney M. Morris
Publikováno v:
Am J Physiol Renal Physiol
Endothelial dysfunction, characterized by reduced bioavailability of nitric oxide and increased oxidative stress, is a hallmark characteristic in diabetes and diabetic nephropathy (DN). High levels of asymmetric dimethylarginine (ADMA) are observed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b868f44a9906174b16091b1a2657f86
https://doi.org/10.1152/ajprenal.00518.2019
https://doi.org/10.1152/ajprenal.00518.2019