Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alaa M.T. Mohamed"'
Autor:
An Xu, Ruoji Zhou, Jian Tu, Zijun Huo, Dandan Zhu, Donghui Wang, Julian A. Gingold, Helen Mata, Pulivarthi H. Rao, Mo Liu, Alaa M.T. Mohamed, Celine Shuet Lin Kong, Brittany E. Jewell, Weiya Xia, Ruiying Zhao, Mien-Chie Hung, Dung-Fang Lee
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 215-219 (2018)
Genetic mutations in TP53 contribute to multiple human cancers. Here we report the generation of a H1-p53(R248W/R248W) human embryonic stem cell line harboring a homozygous TP53 R248W mutation created by TALEN-mediated precise gene editing. The H1-p5
Externí odkaz:
https://doaj.org/article/b5b97d696c454a659960719b242e9363
Autor:
Ruoji Zhou, An Xu, Donghui Wang, Dandan Zhu, Helen Mata, Zijun Huo, Jian Tu, Mo Liu, Alaa M.T. Mohamed, Brittany E. Jewell, Julian Gingold, Weiya Xia, Pulivarthi H. Rao, Mien-Chie Hung, Ruiying Zhao, Dung-Fang Lee
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 131-135 (2018)
The tumor suppressor gene TP53 is the most frequently mutated gene in human cancers. Many hot-spot mutations of TP53 confer novel functions not found in wild-type p53 and contribute to tumor development and progression. We report on the generation of
Externí odkaz:
https://doaj.org/article/c767ab00ed2b40b89340f8bbee1fef71
Autor:
Alaa M.T. Mohamed, Corrine Baumgartner, Baharan Fekry, Mamoun Younes, Aleix Ribas-Latre, Mikhail G. Kolonin, Frances M. Sladek, Kristin Eckel-Mahan
Publikováno v:
Cancer Res
The incidence of hepatocellular carcinoma (HCC) is on the rise worldwide. Although the incidence of HCC in males is considerably higher than in females, the projected rates of HCC incidence are increasing for both sexes. A recently appreciated risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d26eb851e67c3e4a35988ea05c40d7
https://pubmed.ncbi.nlm.nih.gov/31575546
https://pubmed.ncbi.nlm.nih.gov/31575546