Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Alaa Fadhil Alwan"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3234 (2024)
The B cell receptor (BCR) signaling pathway plays a crucial role in B cell development and contributes to the pathogenesis of B cell neoplasms. In B cell malignancies, the BCR is constitutively active through both ligand-dependent and ligand-independ
Externí odkaz:
https://doaj.org/article/60b66f512698463a992f7ddbe4e4b7f7
Autor:
Ahmed Mjali, Bassam Francis Matti, Nareen Tawfeeq Abbas, Hassan Ali Abood Nassrullah, Alaadin Sahham Naji, Alaa Fadhil Alwan, Waseem Fadhil Al-Tameemi, Haider Hasan Jaleel Al-Shammari, Tareq Abdullah Saleh, Mohammed Kamil Al Qayyim, Amer Shareef Mohammed
Publikováno v:
Journal of Applied Hematology, Vol 14, Iss 2, Pp 146-156 (2023)
AIMS: Immune thrombocytopenia (ITP), also known as immune thrombocytopenic purpura, is an autoimmune disorder characterized by a low platelet count in the blood. This study aimed to assess the health infrastructure in Iraq regarding the diagnosis and
Externí odkaz:
https://doaj.org/article/d7f38976bdb248828392c81426dc7d95
Publikováno v:
Iraqi Journal of Hematology, Vol 11, Iss 1, Pp 76-82 (2022)
BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous malignant disease of hematopoietic tissue. It is characterized by accumulation of abnormal blast cells mainly in bone marrow. Hepcidin is a small bioactive peptide hormone produced in many t
Externí odkaz:
https://doaj.org/article/9bcc6e7b74e44c3c8c51ac8ee8ca2d66
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10374 (2023)
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. Despite its indolent clinical course, therapy refractoriness and disease progression still represent an unmet clinical need. Before the advent of pathway inhibitors, chemoimmun
Externí odkaz:
https://doaj.org/article/4b351dba28594b4db0cdad5caa1ccd89
Outcome of imatinib mesylate in women with child-bearing age diagnosed with chronic myeloid leukemia
Publikováno v:
Iraqi Journal of Hematology, Vol 10, Iss 2, Pp 123-126 (2021)
BACKGROUND: Imatinib Mesylate (IM) is an oral tyrosine kinase inhibitor, which demonstrates great effect in the treatment of both chronic myeloid leukemia (CML) and gastrointestinal stromal tumors. The effects of this chemotherapeutic drug on women w
Externí odkaz:
https://doaj.org/article/87b6fedcc1b54ace825608870b8c1e32
Publikováno v:
Iraqi Journal of Hematology, Vol 9, Iss 2, Pp 155-159 (2020)
BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common type of leukemia among adults in Western countries; however, it is relatively rare in Asia. It is characterized by abnormal proliferation of lymphocytes in the blood, bone marrow, and
Externí odkaz:
https://doaj.org/article/50dab341d17042898f8b46dbd53a5e82
Publikováno v:
Iraqi Journal of Hematology, Vol 9, Iss 1, Pp 47-50 (2020)
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a monoclonal disorder characterized by relentless accumulation of monoclonal B-cell. Beta-2 microglobulin (β2m) is an extracellular protein that is bound to the chain of Class 1 major histocompatibil
Externí odkaz:
https://doaj.org/article/e3144eddb37c4a7fb3ba2ed646c9fc96
Publikováno v:
Iraqi Journal of Hematology, Vol 8, Iss 1, Pp 25-28 (2019)
BACKGROUND: Acute leukemia is considered one of the most diseases that required frequent blood transfusion. Despite that blood transfusion is one of the main parts in the supportive management of acute leukemia patients, still, there are few data sho
Externí odkaz:
https://doaj.org/article/d0598a83cda0454796f679a66c87ad41
Effects of nilotinib on platelet function in patients with chronic myeloid leukemia in chronic phase
Autor:
Alauldeen Mudhafar Zubair Alqasim, Ghasaq Mohsin Obaid, Yusra Ghaith Yaseen, Alaa Fadhil Alwan
Publikováno v:
Leukemia Research Reports, Vol 11, Iss , Pp 46-50 (2019)
Background: Tyrosine kinases are highly expressed in platelets and play an important role in their activation process. Some studies have reported the blocking effects of tyrosine kinase inhibitors on different platelet functions. Objectives: Evaluate
Externí odkaz:
https://doaj.org/article/76d19e3f56394049ba3fe85a6b0e6cfb
Autor:
Alaa Fadhil Alwan, Manal Ali Abdulsahib, Duaa Dhahir Abbas, Saraa Ali Abdulsattar, Reem Talib Ensaif
Publikováno v:
Hematology Reports, Vol 12, Iss 3 (2020)
Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin Lymphoma (NHL) are considered parts of mature B cell neoplasms in WHO classification. They are both characterized by accumulation of B cells in blood, lymphoid tissues and bone marrow. Most of treatm
Externí odkaz:
https://doaj.org/article/58a7b2a48b574d62a00734121673f8e7