Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Alaa E. El-sisi"'
JNK inhibitor and ferroptosis modulator as possible therapeutic modalities in Alzheimer disease (AD)
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Alzheimer disease (AD) is among the most prevalent neurodegenerative diseases globally, marked by cognitive and behavioral disruptions. Ferroptosis is a form of controlled cell death characterized by intracellular iron accumulation associate
Externí odkaz:
https://doaj.org/article/ed132d9a3bcb4a698ce2fd93b665c359
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 8, Pp 1170-1180 (2022)
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death. The major challenge in managing HCC is the resistance to chemotherapy. Leptin hormone is associated with different oncogenic pathways implicated in drug resistance.
Externí odkaz:
https://doaj.org/article/c2ba476938344ac3b1978a342abecd69
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04761- (2020)
Objectives: research in the treatment of gastric ulcer has involved the investigation of protective drugs. These drugs may be used as adjacent therapy with the traditional pharmacologic treatment of peptic ulcer. The present study is designed to inve
Externí odkaz:
https://doaj.org/article/30c596ccac5b4b44aca1243e84d3762c
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 2 (2011)
Objective: This study investigated the possibility that genetic factors, such as polymorphism of K inward rectifier subunit (Kir6.2), E23K, and Arg 972 polymorphism of insulin receptor substrate-1 (IRS-1), may predispose patients to sulfonylurea fail
Externí odkaz:
https://doaj.org/article/6c366d2514e34de8bed2e6b4dadc2922
Publikováno v:
Structures. 33:4690-4700
This paper investigates the long-term response of reinforced concrete (RC) beams strengthened with CFRP subjected to sustained static loads. The beams were strengthened using two different configurations of CFRP with different steel reinforcement rat
Publikováno v:
Journal of Advanced Medical and Pharmaceutical Research. 2:64-76
Publikováno v:
Structures. 32:2161-2173
Fingerplate expansion devices are commonly used to account for movements and rotations of two bridge deck slabs. Under high traffic volumes, these devices experience premature damage that affects the structural integrity of the bridge superstructure.
Publikováno v:
Structures. 32:578-587
Steel-concrete composite beams in highway bridges are susceptible to various types of damage during their service life. These damages can greatly affect the structural performance and shorten the fatigue life of bridges. The efficacy of adding extern
Publikováno v:
Frattura ed Integrità Strutturale; Vol. 15 No. 57 (2021): July 2021; 70-81
Frattura ed Integrità Strutturale; V. 15 N. 57 (2021): July 2021; 70-81
Frattura ed Integrità Strutturale, Vol 15, Iss 57, Pp 70-81 (2021)
Frattura ed Integrità Strutturale, Vol 15, Iss 57 (2021)
Frattura ed Integrità Strutturale; V. 15 N. 57 (2021): July 2021; 70-81
Frattura ed Integrità Strutturale, Vol 15, Iss 57, Pp 70-81 (2021)
Frattura ed Integrità Strutturale, Vol 15, Iss 57 (2021)
A substantial amount of work was carried out on the use of fiber-reinforced polymer (FRP) in reinforced concrete structural elements, which demonstrated considerable inelasticity or deformity through monotonic and cyclic loads. Even so, the action of
Publikováno v:
The Egyptian International Journal of Engineering Sciences and Technology. 34:28-37
In this research, three models of beam-column joint have analyzed under reversed cyclic loading by finite element method using ANSYS software. The first model was designed with a steel-reinforced joint (longitudinal reinforcement and stirrups), the s