Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Alaa Abdul-Sada"'
Autor:
David A Smith, Elena-Raluca Nicoli, Oscar C W Chen, Alexandria Colaco, Stephan Siebel, Stephanie Newman, Dawn Shepherd, Nicole Y Farhat, Andrew E Armitage, Claire Smith, George Seligmann, Mylvaganam Jeyakumar, Alaa Abdul-Sada, Forbes D Porter, Hal Drakesmith, Frances M Platt, Nick Platt
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Background: Niemann-Pick disease type C1 (NPC1) is a neurodegenerative lysosomal storage disorder characterized by the accumulation of multiple lipids in the late endosome/lysosomal system and reduced acidic store calcium. The lysosomal system regula
Externí odkaz:
https://doaj.org/article/88e020958a694dd6970e032b17add1f9
Autor:
Jack Devonport, Lauren Sully, Athanassios K. Boudalis, Storm Hassell-Hart, Matthew C. Leech, Kevin Lam, Alaa Abdul-Sada, Graham J. Tizzard, Simon J. Coles, John Spencer, Alfredo Vargas, George E. Kostakis
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 1937-1948 (2021)
Externí odkaz:
https://doaj.org/article/a854ff441f864fcba66dabfbbab60b04
Autor:
Karin Tuschl, Esther Meyer, Leonardo E. Valdivia, Ningning Zhao, Chris Dadswell, Alaa Abdul-Sada, Christina Y. Hung, Michael A. Simpson, W. K. Chong, Thomas S. Jacques, Randy L. Woltjer, Simon Eaton, Allison Gregory, Lynn Sanford, Eleanna Kara, Henry Houlden, Stephan M. Cuno, Holger Prokisch, Lorella Valletta, Valeria Tiranti, Rasha Younis, Eamonn R. Maher, John Spencer, Ania Straatman-Iwanowska, Paul Gissen, Laila A. M. Selim, Guillem Pintos-Morell, Wifredo Coroleu-Lletget, Shekeeb S. Mohammad, Sangeetha Yoganathan, Russell C. Dale, Maya Thomas, Jason Rihel, Olaf A. Bodamer, Caroline A. Enns, Susan J. Hayflick, Peter T. Clayton, Philippa B. Mills, Manju A. Kurian, Stephen W. Wilson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Karin Tuschl, Philippa Mills and colleagues report mutations in the manganese (Mn) transporter gene SLC39A14in childhood-onset parkinsonism-dystonia. Using functional recapitulation, the authors also show that slc39A14 loss-of-function in zebrafish c
Externí odkaz:
https://doaj.org/article/122cc65e3ed24026b35cd38223a5fe6b
Autor:
Edward Loukopoulos, Kieran Griffiths, Geoffrey R. Akien, Nikolaos Kourkoumelis, Alaa Abdul-Sada, George E. Kostakis
Publikováno v:
Inorganics, Vol 3, Iss 4, Pp 448-466 (2015)
A systematic study was performed to further optimise the catalytic room-temperature synthesis of trans-4,5-diaminocyclopent-2-enones from 2-furaldehyde and primary or secondary amines under a non-inert atmosphere. For this purpose, a series of dinucl
Externí odkaz:
https://doaj.org/article/d51cabbc60d64c0abd8ee27683f31f89
Autor:
Yifat Cohen, Márton Megyeri, Oscar C W Chen, Giuseppe Condomitti, Isabelle Riezman, Ursula Loizides-Mangold, Alaa Abdul-Sada, Nitzan Rimon, Howard Riezman, Frances M Platt, Anthony H Futerman, Maya Schuldiner
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85519 (2013)
The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite intense research, the function of more than a third of ER proteins remains unknown even in the well-studied model organism Saccharomyces cerevisiae. One such
Externí odkaz:
https://doaj.org/article/d9703960d913468b9a6a5ad7d2984610
Autor:
Gioia Rossini, Alaa Abdul-Sada, Jack Devonport, Alfredo Vargas, Stavroula I. Sampani, Kevin Lam, Matthew C. Leech, Brian Cox, Victor Zdorichenko, George E. Kostakis
Publikováno v:
Chemistry – A European Journal. 27:4394-4400
The hybrid bidentate 1‐(2‐pyridyl)benzotriazole (pyb) ligand was introduced into 3d transition metal catalysis. Specifically, [CuII(OTf)2(pyb)2]⋅2 CH3CN (1) enables the synthesis of a wide range of propargylamines by the A3 coupling reaction at
Publikováno v:
Iraqi Journal of Nanotechnology. :22-32
Bionanomaterials have great potential for applications in tissue engineering and regenerative medicine. Recently, amyloid-like fibrils have been used in bionanomaterials preparation due to their stability and biocompatibility. Covalent dityrosine bon
Autor:
Oscar C W Chen, Stephan Siebel, Alexandria Colaco, Elena-Raluca Nicoli, Nick Platt, Dawn Shepherd, Stephanie Newman, Andrew E Armitage, Nicole Y Farhat, George Seligmann, Claire Smith, David A Smith, Alaa Abdul-Sada, Mylvaganam Jeyakumar, Hal Drakesmith, Forbes D Porter, Frances M Platt
Publikováno v:
Wellcome Open Research. 7:267
Background: Niemann-Pick disease type C1 (NPC1) is a neurodegenerative lysosomal storage disorder characterized by the accumulation of multiple lipids in the late endosome/lysosomal system and reduced acidic store calcium. The lysosomal system regula
Autor:
Matthew C. Leech, George E. Kostakis, Jack Devonport, Alfredo Vargas, Storm Hassell-Hart, John Spencer, Graham J. Tizzard, Athanassios K. Boudalis, Kevin Lam, Alaa Abdul-Sada, Simon J. Coles, Lauren Sully
Publikováno v:
JACS Au
JACS Au, ACS Publications, In press, ⟨10.1021/jacsau.1c00310⟩
JACS Au, Vol 1, Iss 11, Pp 1937-1948 (2021)
JACS Au, ACS Publications, In press, ⟨10.1021/jacsau.1c00310⟩
JACS Au, Vol 1, Iss 11, Pp 1937-1948 (2021)
International audience; A dimeric Cu(II) complex [Cu(II)2L2(μ2-Cl)Cl] (1) built from an asymmetric tridentate ligand (2-(((2-aminocyclohexyl)imino)methyl)-4,6-di-tert-butylphenol) and weakly coordinating anions has been synthesized and structurally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc31da56b79a10cbf8c53e6034f5212
https://hal.archives-ouvertes.fr/hal-03375148/document
https://hal.archives-ouvertes.fr/hal-03375148/document
Autor:
Stavroula I, Sampani, Victor, Zdorichenko, Jack, Devonport, Gioia, Rossini, Matthew C, Leech, Kevin, Lam, Brian, Cox, Alaa, Abdul-Sada, Alfredo, Vargas, George E, Kostakis
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 27(13)
The hybrid bidentate 1-(2-pyridyl)benzotriazole (pyb) ligand was introduced into 3d transition metal catalysis. Specifically, [Cu