Harmonization of Rapid Evaporative Ionization Mass Spectrometry Workflows across Four Sites and Testing Using Reference Material and Local Food-Grade Meats

Autor: Martin Kaufmann, Pierre-Maxence Vaysse, Adele Savage, Ala Amgheib, András Marton, Eftychios Manoli, Gabor Fichtinger, Steven D. Pringle, John F. Rudan, Ron M. A. Heeren, Zoltán Takáts, Júlia Balog, Tiffany Porta Siegel

Publikováno v: Metabolites, Vol 12, Iss 11, p 1130 (2022)

Rapid evaporative ionization mass spectrometry (REIMS) is a direct tissue metabolic profiling technique used to accurately classify tissues using pre-built mass spectral databases. The reproducibility of the analytical equipment, methodology and tiss

Externí odkaz: https://doaj.org/article/a5c44019ad9f4ab697e42f8764328c5f

Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression

Autor: Robert Brown, Sadaf Ghaem-Maghami, Marina Natoli, David J Pinato, John Gallon, Haonan Lu, Ala Amgheib, Francesco A Mauri, Teresa Marafioti, Ayse U Akarca, Ines Ullmo, Jacey Ip, Eric O Aboagye, Anastasios Karadimitris

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)

Background Endogenous retroviruses (ERVs) play a role in a variety of biological processes, including embryogenesis and cancer. DNA methyltransferase inhibitors (DNMTi)-induced ERV expression triggers interferon responses in ovarian cancer cells via

Externí odkaz: https://doaj.org/article/7d3baf3de1394dd9863a83a84f696bd1

Radiolabelling an 18F biologic via facile IEDDA 'click' chemistry on the GE FASTLab™ platform

Autor: Ala Amgheib, Ruisi Fu, Marta Braga, Sadaf Ghaem-Maghami, Chris P. Barnes, Louis Allott, Eric O. Aboagye, Ning Wang, Diana Brickute

Publikováno v: Reaction Chemistry & Engineering

The use of biologics in positron emission tomography (PET) imaging is an important area of radiopharmaceutical development and new automated methods are required to facilitate their production. We report an automated radiosynthesis method to produce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a55defbee181c63f9e7d7a6809aef87
https://doi.org/10.1039/d1re00117e

The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1

Autor: Manuel Desco, Christopher Heeschen, Manuel Pérez, Tony Bou Kheir, Diego Megías, Meng-Lay Lin, Maria Victoria Gómez-Gaviro, Joaquim Soriano, Deepak Raj, Michele Cioffi, Alexandra Aicher, Mireia Vallespinos, Julfa Begum, Lorena Cussó, Jaimy Saif, Ala Amgheib, Ann-Marie Baker, Sara Trabulo

Publikováno v: Cioffi, M, Trabulo, S M, Vallespinos, M, Raj, D, Kheir, T B, Lin, M L, Begum, J, Baker, A M, Amgheib, A, Saif, J, Perez, M, Soriano, J, Desco, M, Gomez-Gaviro, M V, Cusso, L, Megias, D, Aicher, A & Heeschen, C 2017, ' The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1 ', Oncotarget, vol. 8, no. 13, pp. 21609-21625 . https://doi.org/10.18632/oncotarget.15450
Oncotarget
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

// Michele Cioffi 1 , Sara M. Trabulo 1, 2 , Mireia Vallespinos 1 , Deepak Raj 2 , Tony Bou Kheir 2 , Meng-Lay Lin 2 , Julfa Begum 2 , Ann-Marie Baker 3 , Ala Amgheib 2 , Jaimy Saif 4 , Manuel Perez 5 , Joaquim Soriano 5 , Manuel Desco 6, 7, 8 , Mari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df29bc55006c39f27bd4b2b4fed7cd33
https://hdl.handle.net/1983/52753347-9634-4fbb-a1e3-c991f46766e2