Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Alaín González"'
Autor:
Santiago Salazar, María Francisca Starck, Milton F. Villegas, Jannel Acosta, Oliberto Sánchez, Eduardo Ramos, Estefanía Nova-Lamperti, Jorge R. Toledo, Paula Gädicke, Álvaro Ruiz, Alaín González, Raquel Montesino
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1817 (2023)
Previously, we designed a subunit vaccine candidate based on three L. intracellularis antigens with promising results in pigs. In this study, antigens were produced individually to achieve an even antigen ratio in the formulation. The emulsion charac
Externí odkaz:
https://doaj.org/article/d41362111947472c8ac17e82e4eb295f
Autor:
Yunier Serrano-Rivero, Julieta Salazar-Uribe, Marcela Rubio-Carrasquilla, Frank Camacho-Casanova, Oliberto Sánchez-Ramos, Alaín González-Pose, Ernesto Moreno
Publikováno v:
Molecules, Vol 28, Iss 10, p 4043 (2023)
The epidermal growth factor (EGF) is one of the most critical ligands of the EGF receptor (EGFR), a well-known oncogene frequently overexpressed in cancerous cells and an important therapeutic target in cancer. The EGF is the target of a therapeutic
Externí odkaz:
https://doaj.org/article/ea7c0b0541b14c55b48ce49feb97f8ee
Autor:
María Angélica Contreras, Yunier Serrano-Rivero, Alaín González-Pose, Julieta Salazar-Uribe, Marcela Rubio-Carrasquilla, Matheus Soares-Alves, Natalie C. Parra, Frank Camacho-Casanova, Oliberto Sánchez-Ramos, Ernesto Moreno
Publikováno v:
Molecules, Vol 28, Iss 9, p 3708 (2023)
Nanobodies (Nbs) are single domain antibody fragments derived from heavy-chain antibodies found in members of the Camelidae family. They have become a relevant class of biomolecules for many different applications because of several important advanta
Externí odkaz:
https://doaj.org/article/f23f7bdcbf3d402c98672c25abc51ec3
Publikováno v:
Molecules, Vol 27, Iss 7, p 2198 (2022)
Single domain antibodies from camelids, or nanobodies, are a unique class of antibody fragments with several advantageous characteristics: small monomeric size, high stability and solubility and easy tailoring for multiple applications. Nanobodies ar
Externí odkaz:
https://doaj.org/article/b6a01a12183b450886d0a7bf7a78ad07
Autor:
Alaín González Pose, Nayrobis Oramas Morell, Dailenis Abella Matos, Elsa Rodríguez Rodríguez, Elaine Santana Rodríguez, Liliam Rios Cordero, María Pilar Rodríguez Moltó, Ernesto Manuel González Ramos, Anays Álvarez Gutiérrez, Llilian Gómez Pérez, Julia Noda Gómez, Armando Vega Redondo, Carlos Borroto Nordelo
Publikováno v:
Biotechnology Reports, Vol 3, Iss C, Pp 108-116 (2014)
Avian influenza virus H5N1 has caused extensive damage worldwide among poultry and humans. Effective expression systems are needed for the production of viral proteins required for monitoring this devastating disease. The present study deals with the
Externí odkaz:
https://doaj.org/article/a2b301fa1d06421a831f674acc603b63
Autor:
Alaín González, Julia Noda, Armando Vega, Alina Venereo, Elsa Rodríguez, María P Rodríguez, Ernesto M González, Damarys Díaz, Raquel Montesino, Elaine Santana, Carlos Montero, Alina Rodríguez, Mario P Estrada, Carlos Borroto
Publikováno v:
Biotecnología Aplicada, Vol 29, Iss 4, Pp 275-278
The highly pathogenic H5N1 avian influenza virus (AIV) has caused important economic losses and public health problems, mainly in Asia, Africa and Europe. Counteracting this virus by vaccination of poultry is crucial. In our study, recombinant antige
Externí odkaz:
https://doaj.org/article/3a1e6ac7b8e74d39b88583ba900d7b2a
Autor:
Pose, Alaín González, Morell, Nayrobis Oramas, Matos, Dailenis Abella, Rodríguez, Elsa Rodríguez, Rodríguez, Elaine Santana, Cordero, Liliam Rios, Moltó, María Pilar Rodríguez, Ramos, Ernesto Manuel González, Gutiérrez, Anays Álvarez, Pérez, Llilian Gómez, Gómez, Julia Noda, Redondo, Armando Vega, Nordelo, Carlos Borroto
Publikováno v:
In Biotechnology Reports September 2014 3:108-116
Autor:
Natalie C. Parra, Oliberto Sánchez, María Angélica Contreras, Rafael Maura, Alaín González, Viana Manrique-Suárez, Luis Macaya, Jorge R. Toledo
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 89:1508-1521
Tumor necrosis factor-alpha (TNF⍺) inhibitors could prevent neurological disorders systemically, but their design generally relies on molecules unable to cross the blood-brain barrier (BBB). This research was aimed to design and characterize a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97fdf6a856c3f1c93e9e8120a6fcc9a
https://doi.org/10.1002/prot.26173
https://doi.org/10.1002/prot.26173
Autor:
Raquel Montesinos, Jorge R. Toledo, Frank Camacho, Luis Macaya, Oliberto Sánchez, Alaín González, María Angélica Contreras, Viana Manrique
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 89:1557-1564
The neutralization of tumor necrosis factor alpha (TNFα) with biopharmaceuticals is a successful therapy for inflammatory diseases. Currently, one of the main TNFα-antagonists is Etanercept, a dimeric TNF-R2 ectodomain. Considering that TNFα and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe776a5dfcb7c56a04c63455c6fc1ae
https://doi.org/10.1002/prot.26177
https://doi.org/10.1002/prot.26177
Establishment of a production process for a novel vaccine candidate against Lawsonia intracellularis
Autor:
Jannel Acosta, Eduardo Ramos, Raquel Montesino, Jorge R. Toledo, Thelvia Ramos, Nicolas A. Gutiérrez, Santiago Salazar, Alaín González, Oliberto Sánchez, Claudia Altamirano
Publikováno v:
Electronic Journal of Biotechnology, Vol 50, Iss, Pp 45-52 (2021)
Background Lawsonia intracellularis remains a problem for the swine industry worldwide. Previously, we designed and obtained a vaccine candidate against this pathogen based on the chimeric proteins: OMP1c, OMP2c, and INVASc. These proteins formed inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac92082837ca4e1889e5c29cee77de5b
https://doi.org/10.1016/j.ejbt.2021.01.002
https://doi.org/10.1016/j.ejbt.2021.01.002