Zobrazeno 1 - 10
of 30
pro vyhledávání: '"AlFatah Mansour A"'
Autor:
Toda, Tomohisa, Bedrosian, Tracy A., Schafer, Simon T., Cuoco, Michael S., Linker, Sara B., Ghassemzadeh, Saeed, Mitchell, Lisa, Whiteley, Jack T., Novaresi, Nicole, McDonald, Aidan H., Gallina, Iryna S., Yoon, Hyojung, Hester, Mark E., Pena, Monique, Lim, Christina, Suljic, Emelia, AlFatah Mansour, Abed, Boulard, Matthieu, Parylak, Sarah L., Gage, Fred H.
Publikováno v:
In Cell Reports 27 February 2024 43(2)
Autor:
Tomohisa Toda, Tracy A. Bedrosian, Simon T. Schafer, Michael S. Cuoco, Sara B. Linker, Saeed Ghassemzadeh, Lisa Mitchell, Jack T. Whiteley, Nicole Novaresi, Aidan H. McDonald, Iryna S. Gallina, Hyojung Yoon, Mark E. Hester, Monique Pena, Christina Lim, Emelia Suljic, Abed AlFatah Mansour, Matthieu Boulard, Sarah L. Parylak, Fred H. Gage
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113774- (2024)
Summary: Long interspersed nuclear element-1 (L1 or LINE-1) is a highly abundant mobile genetic element in both humans and mice, comprising almost 20% of each genome. L1s are silenced by several mechanisms, as their uncontrolled expression has the po
Externí odkaz:
https://doaj.org/article/6688623518d44adfa7c2bcdc893f7bd4
Autor:
Madison N. Wilson, Martin Thunemann, Xin Liu, Yichen Lu, Francesca Puppo, Jason W. Adams, Jeong-Hoon Kim, Mehrdad Ramezani, Donald P. Pizzo, Srdjan Djurovic, Ole A. Andreassen, Abed AlFatah Mansour, Fred H. Gage, Alysson R. Muotri, Anna Devor, Duygu Kuzum
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Neuronal organoids derived from human induced pluripotent stem cells can be transplanted and integrated into the rodent cortex for the study of brain development and function. Here the authors demonstrate use of transparent graphene microelectrodes a
Externí odkaz:
https://doaj.org/article/43225109ef62426dbfb9593348738fe7
Autor:
Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menachem Mendel Percia, Ran Ben Ezer, Maxim N. Shokhirev, Fan Qiu, Simon Schafer, Abed AlFatah Mansour, Kile P. Mangan, Tchelet Stern, Polina Ofer, Yam Stern, Ana Paula Diniz Mendes, Jose Djamus, Lynne Randolph Moore, Ritu Nayak, Sapir Havusha Laufer, Aidan Aicher, Amanda Rhee, Thomas L. Wong, Thao Nguyen, Sara B. Linker, Beate Winner, Beatriz C. Freitas, Eugenia Jones, Irit Sagi, Cedric Bardy, Alexis Brice, Juergen Winkler, Maria C. Marchetto, Fred H. Gage
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Several mutations that cause Parkinson’s disease (PD) have been identified over the past decade. These account for 15–25% of PD cases; the rest of the cases are considered sporadic. Currently, it is accepted that PD is not a single monol
Externí odkaz:
https://doaj.org/article/2fa050a5687248eaa0da9d23e96a5eb4
Autor:
Simon T. Schafer, Abed AlFatah Mansour, Johannes C.M. Schlachetzki, Monique Pena, Saeed Ghassemzadeh, Lisa Mitchell, Amanda Mar, Daphne Quang, Sarah Stumpf, Irene Santisteban Ortiz, Addison J. Lana, Clara Baek, Raghad Zaghal, Christopher K. Glass, Axel Nimmerjahn, Fred H. Gage
Publikováno v:
Cell. 186:2111-2126.e20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3203af857e48958b70a7a4ad36a7f381
https://doi.org/10.1016/j.cell.2023.04.022
https://doi.org/10.1016/j.cell.2023.04.022
Autor:
Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menachem Mendel Percia, Ran Ben Ezer, Maxim N. Shokhirev, Fan Qiu, Simon Schafer, Abed AlFatah Mansour, Kile P. Mangan, Tchelet Stern, Polina Ofer, Yam Stern, Ana Paula Diniz Mendes, Jose Djamus, Lynne Randolph Moore, Ritu Nayak, Sapir Havusha Laufer, Aidan Aicher, Amanda Rhee, Thomas L. Wong, Thao Nguyen, Sara B. Linker, Beate Winner, Beatriz C. Freitas, Eugenia Jones, Irit Sagi, Cedric Bardy, Alexis Brice, Juergen Winkler, Maria C. Marchetto, Fred H. Gage
Publikováno v:
NPJ Parkinson's disease. 8(1)
Several mutations that cause Parkinson’s disease (PD) have been identified over the past decade. These account for 15–25% of PD cases; the rest of the cases are considered sporadic. Currently, it is accepted that PD is not a single monolithic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d394959dd0d88394063b9d3023639cb
https://pubmed.ncbi.nlm.nih.gov/35948563
https://pubmed.ncbi.nlm.nih.gov/35948563
Autor:
Alysson R. Muotri, Madison Wilson, Duygu Kuzum, Martin Thunemann, Anna Devor, Abed AlFatah Mansour, Francesca Puppo
Publikováno v:
Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics.
Recent advances in pluripotent stem cell technology have enabled generation of neuronal cell lines and cerebral organoids from human induced pluripotent stem cells (hiPSCs). These organoids are self-assembled, 3D cellular structures that resemble ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242ba084b7bf23cd7d5572f7c34f0ae2
https://doi.org/10.1117/12.2579350
https://doi.org/10.1117/12.2579350
Autor:
Emma Bortz, Duygu Kuzum, Donald P. Pizzo, Alysson R. Muotri, Fred H. Gage, Anna Devor, Benjamin Wolozin, Madison Wilson, Hannah Rickner, Xue Han, Martin Thunemann, Abed AlFatah Mansour, Francesca Puppo
Publikováno v:
Biophotonics Congress 2021.
We present an in vivo platform merging stem cell technology, two-photon imaging, and electrophysiology with transparent graphene microelectrodes for longitudinal interrogation of human brain organoids implanted in the cortex of immunodeficient mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9e89c7efc977b79b8f1da5489f758df
https://doi.org/10.1364/brain.2021.bm2b.4
https://doi.org/10.1364/brain.2021.bm2b.4
Autor:
Simon T. Schafer, Fred H. Gage, Shani Stern, Monique Pena, Christopher K. Glass, Baptiste N. Jaeger, Marvin Liyanage, Jerome Mertens, David Gosselin, Apuã C. M. Paquola, Manching Ku, Abed AlFatah Mansour, Thomas J.M. Kuret, Maria C. Marchetto
Publikováno v:
Nature neuroscience
Autism spectrum disorder (ASD) is thought to emerge during early cortical development. However, the exact developmental stages and associated molecular networks that prime disease propensity are elusive. To profile early neurodevelopmental alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a05ef63b2c2ab3d9a8d430baada9e8
https://doi.org/10.1038/s41593-018-0295-x
https://doi.org/10.1038/s41593-018-0295-x
Publikováno v:
Seminars in celldevelopmental biology. 111
Brain organoids are three-dimensional neural aggregates derived from pluripotent stem cells through self-organization and recapitulate architectural and cellular aspects of certain brain regions. Brain organoids are currently a highly exciting area o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b895bf3cb799052818317611b4be4ad
https://pubmed.ncbi.nlm.nih.gov/32499191
https://pubmed.ncbi.nlm.nih.gov/32499191