Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Al-Hassan Kyakulaga"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
Lung cancer is the leading cause of cancer-related deaths worldwide and in the United States. Despite recent advancements in treatment approaches, metastasis remains a major therapeutic challenge in lung cancer and explains the extremely poor prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb55bb7e17a4c8b203ad41c9ee3b7f16
http://link.springer.com/article/10.1038/s41598-018-34018-1
http://link.springer.com/article/10.1038/s41598-018-34018-1
Autor:
Ashley M. Mudd, Inder Pal Singh, Ashish Kumar Agrawal, Al Hassan Kyakulaga, Jeyaprakash Jeyabalan, Ramesh C. Gupta, Radha Munagala, Farrukh Aqil, Manicka V. Vadhanam
Publikováno v:
Cancer Letters. 393:94-102
Over the last two decades, berries and berry bioactives, particularly anthocyanins and their aglycones anthocyanidins (Anthos) have demonstrated excellent anti-oxidant, anti-proliferative, apoptotic and anti-inflammatory properties. However, their ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a717d460deb270185b048fbeb2734286
https://doi.org/10.1016/j.canlet.2017.02.004
https://doi.org/10.1016/j.canlet.2017.02.004
Autor:
Ashish Kumar Agrawal, Jeyaprakash Jeyabalan, Farrukh Aqil, Lynn P. Parker, Al-Hassan Kyakulaga, Radha Munagala, Ramesh C. Gupta
Publikováno v:
Food & Function. 8:4100-4107
Despite optimal diagnosis and early therapeutic interventions, the prognosis for ovarian cancer patients remains dismal because the efficacy of chemotherapy is limited by the development of resistance and off-site toxicity. Berry bioactives indicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f9f162eee9ceacecf587d964748337
https://doi.org/10.1039/c7fo00882a
https://doi.org/10.1039/c7fo00882a
Publikováno v:
Oncotarget
Platinum-taxane combination chemotherapy still represents the standard of care for advanced non-small cell lung cancer (NSCLC) with no targetable driver mutations. However, the efficacy of these drugs has plateaued at 10-14 months primarily due to do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c0dd8f43fbf26c11227672af132d49
https://pubmed.ncbi.nlm.nih.gov/32362998
https://pubmed.ncbi.nlm.nih.gov/32362998
Autor:
Radha Munagala, Ashish Kumar Agrawal, Hina Kausar, Al-Hassan Kyakulaga, Jeyaprakash Jeyabalan, Farrukh Aqil, Ramesh C. Gupta
Publikováno v:
Experimental and molecular pathology. 101(1)
Celastrol (CEL), a plant-derived triterpenoid, is a known inhibitor of Hsp90 and NF-κB activation pathways and has recently been suggested to be of therapeutic importance in various cancers. However, the molecular mechanisms of celastrol-mediated ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386a48d07b90e0934b38d63f191852ab
https://pubmed.ncbi.nlm.nih.gov/27235383
https://pubmed.ncbi.nlm.nih.gov/27235383
Publikováno v:
Cancer Research. 78:2040-2040
Background: Metastasis remains the primary cause in lung cancer. Epithelial-to-mesenchyme transition (EMT) has been identified as the hallmark for metastasis in NSCLC, and is being explored for drug targeting. Aberrant signaling mechanisms for cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b076f206c76fdcd9039273daffc9f80
https://doi.org/10.1158/1538-7445.am2018-2040
https://doi.org/10.1158/1538-7445.am2018-2040