Protein structural insights into a rare PCSK9 gain-of-function variant (R496W) causing familial hypercholesterolemia in a Saudi family: whole exome sequencing and computational analysis.

Autor: Shaik NA; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.; Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Shehri N; Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Athar M; Department of Medical Genetics, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.; Science and Technology Unit, Umm Al-Qura University, Makkah, Saudi Arabia., Awan A; Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Khalili M; Department of Pharmacology, College of Medicine, Khalifa University, Abu Dhabi, United Arab Emirates., Al Mahadi HB; Department of Research and Development, Al Borg Medical Laboratories, Jeddah, Saudi Arabia., Hejazy G; Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Saadah OI; Department of Pediatrics, Pediatric Gastroenterology Unit, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Harthi SE; Department of Clinical Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Elango R; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.; Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Banaganapalli B; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.; Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Alefishat E; Department of Pharmacology, College of Medicine, Khalifa University, Abu Dhabi, United Arab Emirates.; Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, The University of Jordan, Amman, Jordan.; Center for Biotechnology, Khalifa University, Abu Dhabi, United Arab Emirates., Awan Z; Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Publikováno v: Frontiers in physiology [Front Physiol] 2023 Jul 04; Vol. 14, pp. 1204018. Date of Electronic Publication: 2023 Jul 04 (Print Publication: 2023).

Dilemmas of the causality assessment tools in the diagnosis of adverse drug reactions.

Autor: Khan LM; Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia., Al-Harthi SE; Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia., Osman AM; Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia; National Cancer Institute, Cairo University, Egypt., Sattar MA; Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia; Faculty of Medicine, Ain Shams University, Cairo, Egypt., Ali AS; Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia.

Publikováno v: Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society [Saudi Pharm J] 2016 Jul; Vol. 24 (4), pp. 485-93. Date of Electronic Publication: 2015 Jan 10.

The possible antianginal effect of allopurinol in vasopressin-induced ischemic model in rats.

Autor: Al-Zahrani YA; Department of Medical Pharmacology, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Harthi SE; Department of Medical Pharmacology, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia ; Princess Al Jawhara Albrahim Center of Excellence in Research of Hereditary Disorders, Jeddah, Saudi Arabia., Khan LM; Department of Medical Pharmacology, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., El-Bassossy HM; Department of Pharmacology and Toxicology, College of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia., Edris SM; Princess Al Jawhara Albrahim Center of Excellence in Research of Hereditary Disorders, Jeddah, Saudi Arabia ; Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia., A Sattar MA; Department of Medical Pharmacology, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia ; Faculty of medicine, Ain Shams University, Cairo, Egypt.

Publikováno v: Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society [Saudi Pharm J] 2015 Oct; Vol. 23 (5), pp. 487-98. Date of Electronic Publication: 2015 Jan 07.

Perceptions and knowledge regarding antimicrobial stewardship among clinicians in Jeddah, Saudi Arabia.

Autor: Al-Harthi SE; Department of Pharmacology, College of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. E-mail. salharthi@hotmail.com., Khan LM, Osman AM, Alim MA, Saadah OI, Almohammadi AA, Khan FM, Kamel FO

Publikováno v: Saudi medical journal [Saudi Med J] 2015 Jul; Vol. 36 (7), pp. 813-20.

Replication of GWAS Coding SNPs Implicates MMEL1 as a Potential Susceptibility Locus among Saudi Arabian Celiac Disease Patients.

Autor: Saadah OI; Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Shaik NA; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Banaganapalli B; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Salama MA; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Biology, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Harthi SE; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Wang J; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia; BGI, Beishan Industrial Zone, Yantian District, Shenzhen 518083, China., Shawoosh HA; Department of Pediatrics, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia., Alghamdi SA; Department of Pediatrics, Division of Gastroenterology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia., Bin-Taleb YY; Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alhussaini BH; Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Elango R; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia., Al-Aama JY; Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Publikováno v: Disease markers [Dis Markers] 2015; Vol. 2015, pp. 351673. Date of Electronic Publication: 2015 Dec 30.