Exploring the cytoprotective role of mesenchymal stem Cell-Derived exosomes in chronic liver Fibrosis: Insights into the Nrf2/Keap1/p62 signaling pathway.

Autor: Al Saihati HA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Albatin, Saudi Arabia. Electronic address: hajirsh@uhb.edu.sa., Badr OA; Department of Genetics and Genetic Engineering, Faculty of Agriculture, Benha University, Egypt. Electronic address: omnia.badr@fagr.bu.edu.eg., Dessouky AA; Department of Medical Histology and Cell Biology, Faculty of Medicine, Zagazig University, 44519 Zagazig, Egypt. Electronic address: ariguedessouky@zu.edu.eg., Mostafa O; Department of Histology and Cell Biology, Faculty of Medicine, Benha University, Egypt. Electronic address: Ola.mostafa@fmed.bu.edu.eg., Samir Farid A; Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh 13736, Qalyubia, Egypt. Electronic address: ayman.samir@fvtm.bu.edu.eg., Aborayah NH; Department of Clinical Pharmacology, Faculty of Medicine, Benha University, Egypt, Department of Pharmacology, Mutah University, Mutah 61710, Jordan. Electronic address: nashwa.aborayah@fmed.bu.edu.eg., Abdullah Aljasir M; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia. Electronic address: Mjasr@qu.edu.sa., Baioumy B; Department of Anatomy and Embryology, Faculty of Medicine, Benha University, Egypt. Electronic address: bedor.bayuomi@fmed.bu.edu.eg., Mahmoud Taha N; Department of Physiology, Umm Al-Qura University, Makkah, Saudi Arabia. Electronic address: Nmati@Uqu.edu.sa., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia; Department of Anatomy, Faculty of Medicine, Mansoura University, Egypt. Electronic address: msharbini@um.edu.sa., Hamed Al-Serwi R; Department of Basic Dental Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. Electronic address: rhalserwi@pnu.edu.sa., Ramadan MM; Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah City, United Arab Emirates; Department of Cardiology, Faculty of Medicine, Mansoura University, Mansoura City, Egypt. Electronic address: mramadan@sharjah.ac.ae., Salim RF; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha Universit, Egypt. Electronic address: rabab.salim@fmed.bu.edu.eg., Shaheen D; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: daliashaheen@mans.edu.eg., E M Ali F; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt., Ebrahim N; Department of Histology and Cell Biology, Faculty of Medicine, Benha University, Stem Cell Unit, Egypt. Electronic address: Nesrien.salem@fmed.bu.edu.eg.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2024 Nov 15; Vol. 141, pp. 112934. Date of Electronic Publication: 2024 Aug 22.

MSC-extracellular vesicle microRNAs target host cell-entry receptors in COVID-19: in silico modeling for in vivo validation.

Autor: Al Saihati HA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Albatin, Hafar Al-Batin, Saudi Arabia. hajirsh@uhb.edu.sa., Dessouky AA; Department of Medical Histology and Cell Biology, Faculty of Medicine, Zagazig University, Zagazig, Egypt., Salim RF; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha, Egypt., Elgohary I; Researcher of Pathology, Animal Health Research Institute, Agriculture Research Center, Giza, Egypt., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, 11597, Riyadh, Saudi Arabia.; Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Ali FEM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt., Moustafa MMA; Department of Genetics and Genetic Engineering, Faculty of Agriculture, Benha University, Benha, Egypt., Shaheen D; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Forsyth NR; PhD Molecular Genetics, Vice Principals' Office, Kings College, University of Aberdeen, Aberdeen, AB24 3FX, UK.; Cell and Tissue Engineering, School of pharmacy and bioengineering, Keele University, Keele, UK., Badr OA; Department of Genetics and Genetic Engineering, Faculty of Agriculture, Benha University, Benha, Egypt. omnia.badr@fagr.bu.edu.eg., Ebrahim N; Department of Medical Histology and Cell Biology Faculty of Medicine, Benha University, Benha, Egypt. Nesrien.salem@fmed.bu.edu.eg.; Stem Cell Unit, Faculty of Medicine, Benha University, Benha, Egypt. Nesrien.salem@fmed.bu.edu.eg.; Faculty of Medicine, Benha National University, Al Obour City, Egypt. Nesrien.salem@fmed.bu.edu.eg.; Cell and Tissue Engineering, School of pharmacy and bioengineering, Keele University, Keele, UK. Nesrien.salem@fmed.bu.edu.eg.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2024 Sep 20; Vol. 15 (1), pp. 316. Date of Electronic Publication: 2024 Sep 20.

Memory T Cells Discrepancies in COVID-19 Patients.

Autor: Al Saihati HA; Department of Clinical Laboratory Sciences, College of Applied Medical Science, University of Hafr Al Batin, P.O. Box 1803, Hafar Al Batin 31991, Saudi Arabia., Hussein HAM; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt., Thabet AA; Department of Zoology, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt., Wardany AA; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt., Mahmoud SY; Biology Department, College of Sciences, University of Hafr Al-Batin, Hafr Al-Batin 31991, Saudi Arabia.; Department of Microbiology, Sohag University, Sohag 82524, Egypt., Farrag ES; Department of Clinical Laboratory Sciences, College of Applied Medical Science, University of Hafr Al Batin, P.O. Box 1803, Hafar Al Batin 31991, Saudi Arabia.; Department of Microbiology, South Valley University, Qena 83523, Egypt., Mohamed TIA; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt., Fathy SM; Department of Zoology, Faculty of Science, Fayoum University, Fayoum 63514, Egypt., Elnosary ME; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt., Sobhy A; Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Assiut 71524, Egypt., Ahmed AE; Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Assiut 71524, Egypt., El-Adly AM; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt., El-Shenawy FS; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt., Elsadek AA; Department of Virology, Chest Hospital, Assiut 71514, Egypt., Rayan A; Department of Clinical Oncology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt., Zahran ZAM; Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt., El-Badawy O; Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt., El-Naggar MGM; Department of Clinical Pathology, South Egypt Cancer Institute, Assiut University, Assiut 71515, Egypt., Afifi MM; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt., Zahran AM; Department of Clinical Pathology, South Egypt Cancer Institute, Assiut University, Assiut 71515, Egypt.

Publikováno v: Microorganisms [Microorganisms] 2023 Nov 09; Vol. 11 (11). Date of Electronic Publication: 2023 Nov 09.

Prophylactic Evidence of MSCs-Derived Exosomes in Doxorubicin/Trastuzumab-Induced Cardiotoxicity: Beyond Mechanistic Target of NRG-1/Erb Signaling Pathway.

Autor: Ebrahim N; Department of Medical Histology and Cell Biology, Faculty of Medicine, Benha University, Benha 13511, Egypt.; Stem Cell Unit, Faculty of Medicine, Benha University, Benha 13511, Egypt., Al Saihati HA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Albatin, Hafr Albatin 39524, Saudi Arabia., Mostafa O; Department of Medical Histology and Cell Biology, Faculty of Medicine, Benha University, Benha 13511, Egypt., Hassouna A; School of Interprofessional Health Studies, Faculty of Health and Environmental Sciences, AUT University, Auckland 1010, New Zealand., Abdulsamea S; Department of Paediatrics, Faculty of Medicine, Benha University, Benha 13511, Egypt., Abd El Aziz M El Gebaly E; Department of Clinical Pharmacology, Faculty of Medicine, Benha University, Benha 13511, Egypt., Abo-Rayah NH; Department of Clinical Pharmacology, Faculty of Medicine, Benha University, Benha 13511, Egypt., Sabry D; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Badr University in Cairo, Cairo 11562, Egypt.; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza 12613, Egypt., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh 11597, Saudi Arabia.; Department of Anatomy, Mansoura Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt., Madboly AG; Department of Forensic Medicine & Clinical Toxicology, Faculty of Medicine, Benha University, Benha 13511, Egypt., Hussien NI; Department of Physiology, Faculty of Medicine, Banha University, Benha 13511, Egypt., Saadani REH; Department of Basic Medical Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia., Ebrahim HA; Department of Basic Medical Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia., Badr OAM; Department of Genetics and Genetic Engineering, Faculty of Agriculture, Benha University, Benha 13511, Egypt., Elsherbiny NM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tabuk, Tabuk 71491, Saudi Arabia.; Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Salim RF; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Benha University, Benha 13511, Egypt.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 May 25; Vol. 23 (11). Date of Electronic Publication: 2022 May 25.

Translational aspects in targeting the stromal tumour microenvironment: from bench to bedside.

Autor: Bhome R; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK.; University Surgery, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK., Al Saihati HA; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK., Goh RW; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK.; School of Medicine, University of Southampton, University Road, Southampton, SO17 1BJ UK., Bullock MD; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK.; University Surgery, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK., Primrose JN; University Surgery, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK., Thomas GJ; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK., Sayan AE; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK., Mirnezami AH; Cancer Sciences, Faculty of Medicine, University of Southampton, Somers Building, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK.; University Surgery, South Academic Block, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD UK.

Publikováno v: New horizons in translational medicine [New Horiz Transl Med] 2016 Jan; Vol. 3 (1), pp. 9-21.