The synergic effect of non-alcoholic fatty liver disease and hypertension in the development of cardiovascular disease

Autor: F. Cattazzo, R. Lombardi, A. Mantovani, M. Bevilacqua, M. Zoncapè, L. Iogna Prat, D. Roccarina, D. Sacerdoti, AL. Fracanzani, E. Tsochatzis, C. Fava, A. Dalbeni

Publikováno v: Digestive and Liver Disease. 54:S57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1e8748aa0a16881efc663dd6650df78
https://doi.org/10.1016/j.dld.2022.01.111

The rs2294918 E434K variant modulates PNPLA3 expression and liver damage

Autor: Donati B, Bm, Motta, Pingitore P, Meroni M, Pietrelli A, Alisi A, Petta S, Xing C, Dongiovanni P, Del Menico B, Rametta R, Rm, Mancina, Badiali S, Al, Fracanzani, Craxì A, Fargion S, Nobili V, Romeo S, Luca Valenti

Publikováno v: Europe PubMed Central

The PNPLA3 rs738409 polymorphism (I148M) is a major determinant of hepatic fat and predisposes to the full spectrum of liver damage in nonalcoholic fatty liver disease (NAFLD). Aim of this study was to evaluate whether additional PNPLA3 coding varian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2dc7fb55a130be1de8ba08678adee1ee
http://europepmc.org/abstract/med/26605757

Role of artificial intelligence in staging and assessing of treatment response in MASH patients.

Autor: Akpinar R; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Panzeri D; Department of Physics, Università di Milano-Bicocca, Milan, Italy., De Carlo C; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Belsito V; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy., Durante B; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Chirico G; Department of Physics, Università di Milano-Bicocca, Milan, Italy., Lombardi R; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Fracanzani AL; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Maggioni M; Division of Pathology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Arcari I; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy., Roncalli M; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Terracciano LM; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Inverso D; Division of Immunology, Transplantation and Infectious Diseases IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Aghemo A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy., Pugliese N; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Division of Internal Medicine and Hepatology, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Rozzano, Italy., Sironi L; Department of Physics, Università di Milano-Bicocca, Milan, Italy., Di Tommaso L; Department of Pathology, IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy.

Publikováno v: Frontiers in medicine [Front Med (Lausanne)] 2024 Oct 21; Vol. 11, pp. 1480866. Date of Electronic Publication: 2024 Oct 21 (Print Publication: 2024).

What Not to Overlook in the Management of Patients with Type 2 Diabetes Mellitus: The Nephrological and Hepatological Perspectives.

Autor: Alfieri CM; Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, 20122 Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy., Molinari P; Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, 20122 Milan, Italy.; Post-Graduate School of Specialization in Nephrology, University of Milan, 20122 Milan, Italy., Cinque F; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy., Vettoretti S; Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, 20122 Milan, Italy., Cespiati A; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy., Bignamini D; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy., Nardelli L; Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, 20122 Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy., Fracanzani AL; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy., Castellano G; Department of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Policlinico, 20122 Milan, Italy.; Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy., Lombardi R; SC Medicina Indirizzo Metabolico, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 15; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 15.

Hepatic and adipose tissue transcriptome analysis highlights a commonly deregulated autophagic pathway in severe MASLD.

Autor: Meroni M; Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., De Caro E; Life and Medical Sciences Institute (LIMES), University of Bonn, Germany/System Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Chiappori F; Institute for Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Italy., Longo M; Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., Paolini E; Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., Mosca E; Institute for Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Italy., Merelli I; Institute for Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Italy., Lombardi R; Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Badiali S; Department of Surgery, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., Maggioni M; Department of Pathology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy., Orro A; Institute for Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Italy., Mezzelani A; Institute for Biomedical Technologies, National Research Council (ITB-CNR), Segrate, Italy., Valenti L; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Fracanzani AL; Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Dongiovanni P; Medicine and Metabolic Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.

Publikováno v: Obesity (Silver Spring, Md.) [Obesity (Silver Spring)] 2024 May; Vol. 32 (5), pp. 923-937. Date of Electronic Publication: 2024 Mar 04.