The super sickling haemoglobin HbS-Oman: a study of red cell sickling, K+ permeability and associations with disease severity in patients heterozygous for HbA and HbS-Oman (HbA/S-Oman genotype)

Autor: Al Balushi, HWM, Wali, Y, Al Awadi, M, Al-Subhi, T, Rees, DC, Brewin, JN, Hannemann, A, Gibson, JS

Studying different sickle cell genotypes may throw light on the pathogenesis of sickle cell disease (SCD). Here, the clinical profile, red cell sickling and K$^{+}$ permeability in 29 SCD patients (15 patients with severe disease and 14 with a milder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6c304dac529369f9c1378b3e493f15
https://www.repository.cam.ac.uk/handle/1810/265039

The super sickling haemoglobin HbS-Oman: a study of red cell sickling, K ⁺ permeability and associations with disease severity in patients heterozygous for HbA and HbS-Oman (HbA/S-Oman genotype).

Autor: Al Balushi HWM; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Wali Y; Department of Child Health, Sultan Qaboos University, Muscat, Oman., Al Awadi M; Department of Genetics, Sultan Qaboos University, Muscat, Oman., Al-Subhi T; Department of Child Health, Sultan Qaboos University, Muscat, Oman., Rees DC; Department of Paediatric Haematology, King's College Hospital, King's College London School of Medicine, London, UK., Brewin JN; Department of Paediatric Haematology, King's College Hospital, King's College London School of Medicine, London, UK., Hannemann A; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Gibson JS; Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.

Publikováno v: British journal of haematology [Br J Haematol] 2017 Oct; Vol. 179 (2), pp. 256-265. Date of Electronic Publication: 2017 Jul 12.