ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients

Autor: Pau Riera, Alícia Artigas-Baleri, Juliana Salazar, Ana Sebio, Anna C. Virgili, María Jesús Arranz, David Páez

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

Irinotecan is widely used in the treatment of metastatic colorectal cancer (mCRC) despite its severe toxicities. Toxicity is often associated with the UGT1A1*28/*28 genotype. An explanation for idiopathic toxicity beyond the UGT1A1 biomarker, however

Externí odkaz: https://doaj.org/article/ef87d544c8fd470cadea439b80e3e587

Pharmacogenetic Profiling in High-Risk Soft Tissue Sarcomas Treated with Neoadjuvant Chemotherapy

Autor: Anna C. Virgili Manrique, Juliana Salazar, María Jesús Arranz, Silvia Bagué, Ruth Orellana, Antonio López-Pousa, Paula Cerdà, Isidre Gracia, Katarina Majercakova, Ana Peiró, Laura Trullols, Manuel Fernández, Sandra Valverde, María Jesús Quintana, Olga Bell, Alícia Artigas-Baleri, Ana Sebio

Publikováno v: Journal of Personalized Medicine
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Journal of Personalized Medicine; Volume 12; Issue 4; Pages: 618

Neoadjuvant chemotherapy based on anthracyclines and ifosfamide for high-risk soft tissue sarcomas (STS) of the extremities and trunk is a controversial treatment option. There are substantial interindividual differences in clinical outcomes in patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be237e7609bed9495bf82529d5ba0f5
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8487

Survival improvement of patients with FLT3 mutated acute myeloid leukemia: results from a prospective 9 years cohort

Autor: Guadalupe Oñate, Marta Pratcorona, Ana Garrido, Alicia Artigas-Baleri, Alex Bataller, Mar Tormo, Montserrat Arnan, Susana Vives, Rosa Coll, Olga Salamero, Ferran Vall-Llovera, Antònia Sampol, Antoni Garcia, Marta Cervera, Sara Garcia Avila, Joan Bargay, Xavier Ortín, Josep F. Nomdedéu, Jordi Esteve, Jorge Sierra, Spanish Cooperative Group for the Study and Treatment of Acute Leukemias and Myelodysplasias (CETLAM)

Publikováno v: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-9 (2023)

Abstract Midostaurin added to intensive chemotherapy is the standard of care for acute myeloid leukemia (AML) with FLT3 mutations (FLT3mut). We analyzed the impact of midostaurin in 227 FLT3mut-AML patients included in the AML-12 prospective trial fo

Externí odkaz: https://doaj.org/article/44faeaa66ec84739ae0950e1c8e25bf3

Pharmacogenetic Interventions Improve the Clinical Outcome of Treatment-Resistant Autistic Spectrum Disorder Sufferers

Autor: Maria J. Arranz, Juliana Salazar, Valentin Bote, Alicia Artigas-Baleri, Alexandre Serra-LLovich, Emma Triviño, Jordi Roige, Carlos Lombardia, Martha Cancino, Marta Hernandez, Marc Cendros, Enric Duran-Tauleria, Natalia Maraver, Amaia Hervas

Publikováno v: Pharmaceutics, Vol 14, Iss 5, p 999 (2022)

BACKGROUND: Autistic spectrum disorders (ASD) are severe neurodevelopmental alterations characterised by deficits in social communication and repetitive and restricted behaviours. About a third of patients receive pharmacological treatment for comorb

Externí odkaz: https://doaj.org/article/823d76f0ab7e49828e185a874dbed989