Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Alì Mirazimi"'
Autor:
Angela Corona, Elisa Fanunza, Cristiano Salata, Melody Jane Morwitzer, Simona Distinto, Luca Zinzula, Cinzia Sanna, Aldo Frau, Gian Luca Daino, Marina Quartu, Orazio Taglialatela-Scafati, Daniela Rigano, StPatrick Reid, Alì Mirazimi, Enzo Tramontano
Ebola virus (EBOV) is one of the deadliest infective agents whose lethality is linked to the ability to efficiently bypass the host's innate antiviral response. EBOV multifunctional protein VP35 plays a major role in viral replication both as polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefaf665b12bae2128b081d09e52f401
http://hdl.handle.net/11577/3415243
http://hdl.handle.net/11577/3415243
Autor:
Sarah Kempster, Mark Hassall, Victoria Graham, Emma Kennedy, Stephen Findlay-Wilson, Francisco J. Salguero, Binnur Bagci, Nazif Elaldi, Murtaza Oz, Tuba Tasseten, Frank W. Charlton, John N. Barr, Juan Fontana, Chinwe Duru, Ernest Ezeajughi, Paul Matejtschuk, Ulrike Arnold, Yemisi Adedeji, Ali Mirazimi, Roger Hewson, Stuart Dowall, Neil Almond
Publikováno v:
Virus Research, Vol 346, Iss , Pp 199409- (2024)
Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is spread by infected ticks or direct contact with blood, tissues and fluids from infected patients or livestock. Infection with CCHFV causes severe haemorrhagic fever in humans which is fatal in up to 8
Externí odkaz:
https://doaj.org/article/66708ffdc86a453d98aea18c1ee3b92c
Autor:
Amy Flaxman, Sarah Sebastian, Sofia Appelberg, Kuan M Cha, Marta Ulaszewska, Jyothi Purushotham, Ciaran Gilbride, Hannah Sharpe, Alexandra J Spencer, Sagida Bibi, Daniel Wright, Isabel Schmidt, Stuart Dowall, Linda Easterbrook, Stephen Findlay-Wilson, Sarah Gilbert, Ali Mirazimi, Teresa Lambe
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012262 (2024)
Viral haemorrhagic fevers (VHF) pose a significant threat to human health. In recent years, VHF outbreaks caused by Ebola, Marburg and Lassa viruses have caused substantial morbidity and mortality in West and Central Africa. In 2022, an Ebola disease
Externí odkaz:
https://doaj.org/article/453444d7b6cb4f6b990f490aa2a81d37
Autor:
Vanessa Monteil, Hyesoo Kwon, Lijo John, Cristiano Salata, Gustav Jonsson, Sabine U. Vorrink, Sofia Appelberg, Sonia Youhanna, Matheus Dyczynski, Alexandra Leopoldi, Nicole Leeb, Jennifer Volz, Astrid Hagelkruys, Max J. Kellner, Stéphanie Devignot, Georg Michlits, Michelle Foong-Sobis, Friedemann Weber, Volker M. Lauschke, Moritz Horn, Heinz Feldmann, Ulrich Elling, Josef M. Penninger, Ali Mirazimi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks have occurred in the last decades. Although several receptors and co-receptors have been reported for Ebola virus, key host factors remain to be e
Externí odkaz:
https://doaj.org/article/138c2c1cad6c485e9bafa12b9c5adf5c
Autor:
Angela, Corona, Elisa, Fanunza, Salata, Cristiano, Patrick Reid, St., Simona, Distinto, Cinzia, Sanna, Jane, Morwitzer, Aldo, Frau, Daniela, Rigano, Gian Luca Daino, Giuseppina, Chianese, Carmen, Formisano, Orazio Taglialatela Scalfati, Alì, Mirazimi, Tramontano, Enzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3657::0121e6b31db623155c86867bea4f8752
http://hdl.handle.net/11577/3303438
http://hdl.handle.net/11577/3303438
Autor:
Klara Andersson, Ani Azatyan, Martin Ekenberg, Gözde Güçlüler, Laura Sardon Puig, Marjo Puumalainen, Theodor Pramer, Vanessa M. Monteil, Ali Mirazimi
Publikováno v:
Viruses, Vol 16, Iss 10, p 1539 (2024)
In a time of climate change, population growth, and globalization, the risk of viral spread has significantly increased. The 21st century has already witnessed outbreaks of Severe Acute Respiratory Syndrome virus (SARS-CoV), Severe Acute Respiratory
Externí odkaz:
https://doaj.org/article/53793d117fc7430697cd4305b3dca906
Autor:
Rong Zhu, Daniel Canena, Mateusz Sikora, Miriam Klausberger, Hannah Seferovic, Ahmad Reza Mehdipour, Lisa Hain, Elisabeth Laurent, Vanessa Monteil, Gerald Wirnsberger, Ralph Wieneke, Robert Tampé, Nikolaus F. Kienzl, Lukas Mach, Ali Mirazimi, Yoo Jin Oh, Josef M. Penninger, Gerhard Hummer, Peter Hinterdorfer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Combining high-speed AFM, single molecule recognition force spectroscopy, and molecular dynamics simulations Zhu, Canena, Sikora et al. characterize the interaction dynamics of the trimeric spike protein of SARS-CoV-2 wt, and delta and omicron varian
Externí odkaz:
https://doaj.org/article/4f03cce8155a4e8b9132fcede13abbbb
Autor:
Clara Husser, Hyesoo Kwon, Klara Andersson, Sofia Appelberg, Nuria Montserrat, Ali Mirazimi, Vanessa M. Monteil
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 443 (2024)
While having already killed more than 7 million of people worldwide in 4 years, SARS-CoV-2, the etiological agent of COVID-19, is still circulating and evolving. Understanding the pathogenesis of the virus is of capital importance. It was shown that
Externí odkaz:
https://doaj.org/article/cf0b550f1f564134b70b1e7596428987
Autor:
Sofia Appelberg, Gustaf Ahlén, Jingyi Yan, Negin Nikouyan, Sofie Weber, Olivia Larsson, Urban Höglund, Soo Aleman, Friedemann Weber, Emma Perlhamre, Johanna Apro, Eva‐Karin Gidlund, Ola Tuvesson, Simona Salati, Matteo Cadossi, Hanna Tegel, Sophia Hober, Lars Frelin, Ali Mirazimi, Matti Sällberg
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp 1-11 (2022)
Abstract New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO. We designed a more universal SARS‐CoV
Externí odkaz:
https://doaj.org/article/35ec9af66e3647f5894151746b9c3202
Autor:
Vanessa Monteil, Brett Eaton, Elena Postnikova, Michael Murphy, Benedict Braunsfeld, Ian Crozier, Franz Kricek, Janine Niederhöfer, Alice Schwarzböck, Helene Breid, Stephanie Devignot, Jonas Klingström, Charlotte Thålin, Max J Kellner, Wanda Christ, Sebastian Havervall, Stefan Mereiter, Sylvia Knapp, Anna Sanchez Jimenez, Agnes Bugajska‐Schretter, Alexander Dohnal, Christine Ruf, Romana Gugenberger, Astrid Hagelkruys, Nuria Montserrat, Ivona Kozieradzki, Omar Hasan Ali, Johannes Stadlmann, Michael R Holbrook, Connie Schmaljohn, Chris Oostenbrink, Robert H Shoemaker, Ali Mirazimi, Gerald Wirnsberger, Josef M Penninger
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 8, Pp 1-13 (2022)
Abstract The recent emergence of multiple SARS‐CoV‐2 variants has caused considerable concern due to both reduced vaccine efficacy and escape from neutralizing antibody therapeutics. It is, therefore, paramount to develop therapeutic strategies t
Externí odkaz:
https://doaj.org/article/8b99883b78934b478c6d1c13c62796ff