Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Al, de Leon"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Drug delivery to solid tumors using echogenic nanobubbles (NBs) and ultrasound (US) has recently gained significant interest. The approach combines attributes of nanomedicine and the enhanced permeation and retention (EPR) effect with the documented
Externí odkaz:
https://doaj.org/article/30fea3c0adf7499c8d843753c221561b
Autor:
Michael C. Kolios, Amin Jafari Sojahrood, Eric C. Abenojar, Al de Leon, Michaela Cooley, Agata A. Exner, Richard T. Lee
Publikováno v:
ACS Nano
Understanding the pressure dependence of the nonlinear behavior of ultrasonically excited phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure parameters for implementations of contrast enhanced ultrasound, critic
Publikováno v:
ACS macro letters. 6(11)
Emulsions are important in numerous fields, including cosmetics, coatings, and biomedical applications. A subset of these structures, oil-in-oil emulsions, are especially intriguing for water sensitive reactions such as polymerizations and catalysis.
Publikováno v:
ACS macro letters. 4(1)
An amphiphilic dendritic polymer with polyethylenimine (PEI) as the hydrophilic core, steric ester (STA) as the hydrophobic shell, and azobenzene (AZO) groups as the photoswitchable moieties was synthesized via amidation reaction. The synthesized den
Autor:
David Yan, Dana Wegierak, Agata A. Exner, Michael C. Kolios, Filip Bordera, Madelyn McMillen, Al de Leon, Christina Hemmingsen, Peiran Wei, Emily Pentzer
Publikováno v:
ACS Appl Mater Interfaces
Microbubbles (MBs) stabilized by particle surfactants (i.e., Pickering bubbles) have better thermodynamic stability compared to MBs stabilized by small molecules as a result of steric hindrance against coalescence, higher diffusion resistance, and hi
Autor:
Dana Wegierak, Grace Fishbein, Eric Abenojar, Al De Leon, Jinle Zhu, Yanjie Wang, Charlotte Ferworn, Agata A. Exner, Michael C. Kolios
Publikováno v:
Journal of Biomedical Optics
Significance: An effective contrast agent for concurrent multimodal photoacoustic (PA) and ultrasound (US) imaging must have both high optical absorption and high echogenicity. Integrating a highly absorbing dye into the lipid shell of gas core nanob
Akademický článek
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Autor:
Ramamurthy Gopalakrishnan, Yu Wang, Agata A. Exner, James P. Basilion, Reshani Perera, Al de Leon, Xinning Wang, Eric C. Abenojar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Ultrasound imaging is routinely used to guide prostate biopsies, yet delineation of tumors within the prostate gland is extremely challenging, even with microbubble (MB) contrast. A more effective ultrasound protocol is needed that can effectively lo
Autor:
Eric C. Abenojar, Judith Hadley, Agata A. Exner, Ilya Bederman, Michael C. Kolios, Jinle Zhu, Al de Leon
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 208 (2020)
Pharmaceutics
Volume 12
Issue 3
Pharmaceutics
Volume 12
Issue 3
The amount of gas in ultrasound contrast agents is related to their acoustic activity. Because of this relationship, gas volume has been used as a key variable in normalizing the in vitro and in vivo acoustic behavior of lipid shell-stabilized bubble
Publikováno v:
ACS Appl Mater Interfaces
Shell-stabilized gas nanobubbles have recently captured the interest of the research community for their potential application as ultrasound contrast agents for molecular imaging and therapy of cancer. However, the very existence of submicron gas bub