Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Akuammicine"'
Autor:
Eelco Ruijter, Matteo Faltracco
Publikováno v:
Organic & Biomolecular Chemistry
Organic and Biomolecular Chemistry, 19(44), 9641-9644. Royal Society of Chemistry
Faltracco, M & Ruijter, E 2021, ' Synthesis of tetracyclic spiroindolines by an interrupted Bischler-Napieralski reaction : total synthesis of akuammicine ', Organic and Biomolecular Chemistry, vol. 19, no. 44, pp. 9641-9644 . https://doi.org/10.1039/d1ob01966j
Organic and Biomolecular Chemistry, 19(44), 9641-9644. Royal Society of Chemistry
Faltracco, M & Ruijter, E 2021, ' Synthesis of tetracyclic spiroindolines by an interrupted Bischler-Napieralski reaction : total synthesis of akuammicine ', Organic and Biomolecular Chemistry, vol. 19, no. 44, pp. 9641-9644 . https://doi.org/10.1039/d1ob01966j
Judicious substrate design allows interruption of the classical Bischler–Napieralski reaction, providing access to a range of diversely substituted tetracyclic spiroindolines. These complex polycyclic scaffolds are valuable building blocks for the
Publikováno v:
Angewandte Chemie. 133:25339-25346
Chiral tetrahydro-β-carboline (THβC) is not only a prevailing structural feature of many natural alkaloids but also a versatile synthetic precursor for a vast array of monoterpenoid indole alkaloids. Asymmetric synthesis of C1-alkynyl THβCs remain
Akademický článek
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Autor:
Goli Penchala Prasad, S. D. Pawar, Brijesh S. Sisodia, Anupam K Mangal, Manohar S Gundeti, Sudesh N. Gaidhani, Vankudavath Naik Raju, P V V Prasad, Sumeet Goel, Thrigulla Saketh Ram, Manne Munikumar, Naveen Kumar Boiroju, Mukesh Chincholikar, N. Srikanth, K S Dhiman, Rajkumar Hemalatha, Parasannanavar Devaraj
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 1, Pp 100413-(2022)
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine
Background Outbreak of Corona Virus Disease in late 2019 (COVID-19) has become a pandemic global Public health emergency. Since there is no approved anti-viral drug or vaccine declared for the disease and investigating existing drugs against the COVI
Akademický článek
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Publikováno v:
Bioorganic & Medicinal Chemistry. 43:116270
The U rhynchophylla, U tomentosa, Isatis indigotica Fortune, Voacanga Africana, herbal constituents, fungal extracts from Aspergillus duricaulis culture media, include spirooxindoles, polyphenols or bridged spirocyclic alkaloids. Their constituents e
Autor:
Anna Stavrinides, Vincent Courdavault, Audrey Oudin, Inês Carqueijeiro, Sarah E. O'Connor, Jakob Franke, Florent Lafontaine, Thomas Dugé de Bernonville, Evangelos C. Tatsis, Marc Clastre, Thu-Thuy T. Dang, Arnaud Lanoue
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/s41467-017-00154-x⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/s41467-017-00154-x⟩
Monoterpene indole alkaloids comprise a diverse family of over 2000 plant-produced natural products. This pathway provides an outstanding example of how nature creates chemical diversity from a single precursor, in this case from the intermediate str
Publikováno v:
Planta Medica. 81:S1-S381
(16S)-Preakuammicine has been considered a key intermediate in the biosynthesis of monoterpene indole alkaloids since the 1970s. Indeed, preakuammicine plays a crucial role in the biosynthesis of type II and type III monoterpene indole alkaloids and
Publikováno v:
European Journal of Organic Chemistry. 2016:1494-1499
(16S)-Preakuammicine has been considered a key intermediate in the biosynthesis of monoterpene indole alkaloids since the 1970s. Indeed, preakuammicine plays a crucial role in the biosynthesis of type II and type III monoterpene indole alkaloids and
A Synthesis of Alsmaphorazine B Demonstrates the Chemical Feasibility of a New Biogenetic Hypothesis
Publikováno v:
Journal of the American Chemical Society, vol 137, iss 23
An N-oxide fragmentation/hydroxylamine oxidation/intramolecular 1,3-dipolar cycloaddition cascade efficiently converted an oxidized congener of akuammicine into the complex, hexacyclic architecture of the alsmaphorazine alkaloids. This dramatic struc