Zobrazeno 1 - 10
of 810
pro vyhledávání: '"Akt-mTOR pathway"'
Autor:
Yongliang Sha, Huijie Zhuang, Jin Shi, Song Ge, Shiqing He, Yiqiu Wang, Li Ma, Hao Guo, Hui Cheng
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background β-1,3-Galactosyltransferase-4 (B3GALT4), a member of the β-1,3-galactosyltransferase gene family, is essential to the development of many malignancies. However, its biological function in breast cancer is still unknown. Method P
Externí odkaz:
https://doaj.org/article/671ae44fdb66486682acf07209fe6780
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors of the digestive system, and the exact mechanism of HCC is still unclear. Transcription factor 7 like 2 (TCF7L2) plays a pivotal role in cell proliferation
Externí odkaz:
https://doaj.org/article/530da51c71024243a030c0b36983fabe
Publikováno v:
Journal of Bone Oncology, Vol 49, Iss , Pp 100652- (2024)
Background: Osteosarcoma (OS) is a highly malignant primary bone tumor primarily affecting children and adolescents. Despite advancements in therapeutic strategies, long-term survival rates for OS remain unfavorable, especially in advanced or recurre
Externí odkaz:
https://doaj.org/article/a98c351b8e1e4774bb338692068892b6
Autor:
Xiaoying Xu, Shao Ma, Ziwei Liu, Haowen Yuan, Yao Wang, Mengting Chen, Mengyu Du, Haopeng Kan, Zequn Wang, Xiaowen Chong, Hongling Wen
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background EV71 is one of the important pathogens of Hand-foot-and-mouth disease (HFMD), which causes serious neurological symptoms. Several studies have speculated that there will be interaction between 5′UTR and 3D protein. However, whet
Externí odkaz:
https://doaj.org/article/9574eca6bc2e4e8ca780abba813b9bc7
Autor:
Lee‐Moay Lim, Yi‐Chen Lee, Ting‐Wei Lin, Zi‐Xuan Hong, Wei‐Chi Hsu, Hung‐Lung Ke, Daw‐Yang Hwang, Wen‐Yu Chung, Wei‐Ming Li, Hui‐Hui Lin, Hung‐Tien Kuo, A‐Mei Huang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 5, Pp 445-455 (2024)
Abstract Neurotrophic receptor tyrosine kinase 3 (NTRK3) has pleiotropic functions: it acts not only as an oncogene in breast and gastric cancers but also as a dependence receptor in tumor suppressor genes in colon cancer and neuroblastomas. However,
Externí odkaz:
https://doaj.org/article/9e5d7c95c6ce4eaba4f6fa0ce58da1f1
Autor:
Yassine El Mahi, Zohra Nausheen Nizami, Adil Farooq Wali, Aysha Al Neyadi, Mohamed Magramane, Mazoun Al Azzani, Kholoud Arafat, Samir Attoub, Ali H. Eid, Rabah Iratni
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background:Pancreatic cancer is a leading cause of cancer-related mortality worldwide with increasing global incidence. We previously reported the anticancer effect of Rhus coriaria ethanolic extract (RCE) in triple negative breast and colon cancer c
Externí odkaz:
https://doaj.org/article/a71c868f0d0749d3b9373f02c3c15a31
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Osteoarthritis (OA) is a common degenerative joint disease characterized by persistent articular cartilage degeneration and synovitis. Oxymatrine (OMT) is a quinzolazine alkaloid extracted from the traditional Chinese medicine, ma
Externí odkaz:
https://doaj.org/article/c903d209e1d54083837fc9338f61544f
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 153-65 (2024)
Colorectal cancer (CRC) is the third most common tumor, with an increasing number of deaths worldwide each year. Tremendous advances in the diagnosis and treatment of CRC have significantly improved the outcomes for CRC patients. Additionally, accumu
Externí odkaz:
https://doaj.org/article/4dc541310d8f471dbc3a6201bb9426d7
Autor:
Feng Cai, Luhua Liu, Yuan Bo, Wenjing Yan, Xuchang Tao, Yuanxiang Peng, Zhiping Zhang, Qi Liao, Yangyan Yi
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Osteosarcoma (OS) is a highly malignant tumor, and its dysregulated lipid metabolism is associated with tumorigenesis and unfavorable prognosis. Interestingly, long noncoding RNAs (lncRNAs) have emerged as pivotal regulators of lipid metabol
Externí odkaz:
https://doaj.org/article/6e446fa597f840eabf278fd1d9945282
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Despite receiving first-line treatment, ovarian cancer patients continue to experience a high rate of recurrence; nearly all women with ovarian cancer develop chemoresistance and succumb to the disease. In this study, cancer-associated fibro
Externí odkaz:
https://doaj.org/article/4e9b6d2f88124bce87f1a0f4be3d523b