Zobrazeno 1 - 10
of 916
pro vyhledávání: '"Akt protein"'
Autor:
Lorena Caixeta Gomes, Rodrigo Ribeiro Resende, Ricardo Cambraia Parreira, Cláudia Natália Ferreira, Edna Afonso Reis, Rita Carolina Figueiredo Duarte, Luan Carlos Vieira Alves, Sergio Schusterschitz da Silva Araújo, Maria das Graças Carvalho, Adriano de Paula Sabino
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract The present study evaluated 56 patients diagnosed with Chronic Lymphocytic Leukemia (CLL) and a control group of 44 clinically healthy subjects with no previous history of leukemia. Genetic expressions of AKT and microRNAs were evaluated by
Externí odkaz:
https://doaj.org/article/31433178ab3e46db91f115417a37ae53
Autor:
Ayodeji Olalekan Salau, Shruti Jain
Publikováno v:
Informatics in Medicine Unlocked, Vol 23, Iss , Pp 100511- (2021)
Artificial intelligence techniques can unravel clinically consistent information in clinical data which in turn assist in decision-making. With the help of state-of-the-art techniques, diagnostic systems are used to identify various diseases by using
Externí odkaz:
https://doaj.org/article/525d5b4c0af04301ac8b4759222c1ce7
Autor:
Digicaylioglu, Murat, Garden, Gwenn, Timberlake, Sonia, Fletcher, Lauren, Lipton, Stuart A., Ruoslahti, Erkki
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2004 Jun . 101(26), 9855-9860.
Externí odkaz:
https://www.jstor.org/stable/3372547
Autor:
Alaa M. Ismail, Ahmed M. Abbas, Ahmed K. Bakry, Ahmed M. Abu-Elhassan, Amany O. Mohamed, Gamal Badr, Mohammed A. Youssef
Publikováno v:
Middle East Fertility Society Journal, Vol 22, Iss 1, Pp 33-38 (2017)
Objective: Recurrent miscarriage (RM) is one of the most common clinical problems in reproduction. The aims of the current study were to evaluate the expression of ERK and Akt proteins in human trophoblastic tissue and to assess the significance of M
Externí odkaz:
https://doaj.org/article/f4f34d95e1b34ee695741aeb9a283618
Autor:
Sami Gabbouj, Simo Ryhänen, Mikael Marttinen, Rebekka Wittrahm, Mari Takalo, Susanna Kemppainen, Henna Martiskainen, Heikki Tanila, Annakaisa Haapasalo, Mikko Hiltunen, Teemu Natunen
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) and type 2 diabetes (T2D) are both diseases with increasing prevalence in aging populations. T2D, characterized by insulin resistance and defective insulin signaling, is a common co-morbidity and a risk factor for AD, incre
Externí odkaz:
https://doaj.org/article/15215aa0ee3d4acfb1f0bd56cde7b958
Autor:
J. Gustavo Vazquez-Jimenez, M. Stephanie Corpus-Navarro, J. Miguel Rodriguez-Chavez, Hiram J. Jaramillo-Ramirez, Judith Hernandez-Aranda, Octavio Galindo-Hernandez, J. Rene Machado-Contreras, Marina Trejo-Trejo, Agustin Guerrero-Hernandez, J. Alberto Olivares-Reyes
Publikováno v:
Metabolites, Vol 11, Iss 2, p 91 (2021)
Experimental evidence in mice models has demonstrated that a high regulator of G-protein signaling 2 (RSG2) protein levels precede an insulin resistance state. In the same context, a diet rich in saturated fatty acids induces an increase in RGS2 prot
Externí odkaz:
https://doaj.org/article/f9159211bf5c4feb9ce9d62e4763d95d
Autor:
Yanfei Cai, Jingyu Zhu, Yun Chen, Jian Jin, Xinling Zhao, Kan Li, Lei Xu, Huazhong Li, Gang Huang
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 36, Iss, Pp 1-13 (2022)
Journal of Advanced Research, Vol 36, Iss, Pp 1-13 (2022)
Graphical abstract
Highlights • Virtual screening based on machine learning with multiple proteins was developed. • Discovery of a novel PI3Kγ inhibitor integrating virtual screening and bio-assays. • JN-KI3 selective inhibit PI3Kγ enzym
Highlights • Virtual screening based on machine learning with multiple proteins was developed. • Discovery of a novel PI3Kγ inhibitor integrating virtual screening and bio-assays. • JN-KI3 selective inhibit PI3Kγ enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdbf7fb8f578b72a0c3242e69513c71
https://doi.org/10.1016/j.jare.2021.04.007
https://doi.org/10.1016/j.jare.2021.04.007
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775