Zobrazeno 1 - 10
of 1 021
pro vyhledávání: '"Akt phosphorylation"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Non-small cell lung cancer (NSCLC) is typically diagnosed at advanced stages, which limits the effectiveness of therapeutic interventions. The present study aimed to explore the role of the newly identified circLIFRSA in the PTEN/
Externí odkaz:
https://doaj.org/article/86e77238c821496fb924601add03bb6e
Autor:
Theodora Karamanidou, Konstantinos Krommydas, Maria Karanikou, Dimitrios Tsamos, Konstantinos Michalakis, Dimitris Kletsas, Alexander Tsouknidas, Harris Pratsinis
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5812-5824 (2024)
Extracellular vesicles (EVs) have been identified as important mediators for cell-to-cell communication. Citrus-based EVs in particular offer an excellent platform for nutraceutical delivery systems, as their endemic cargo includes micronutrients (e.
Externí odkaz:
https://doaj.org/article/8abfe167f15244caa90e287b4abd0f0b
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract Statins, the first‐line medication for dyslipidemia, are linked to an increased risk of type 2 diabetes. But exactly how statins cause diabetes is yet unknown. In this study, a developed short‐term statin therapy on hyperlipidemia mice s
Externí odkaz:
https://doaj.org/article/c508dd08f8d04ec8a47e1a7ff2910fb8
Autor:
Kyung Eun Lee, Miyuki Nishi, Jongsoo Kim, Takashi Murayama, Zachary Dawson, Xiaoliang Wang, Xinyu Zhou, Tao Tan, Chuanxi Cai, Hiroshi Takeshima, Ki Ho Park
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
RationaleMG53’s known function in facilitating tissue repair and anti-inflammation has broad applications to regenerative medicine. There is controversy regarding MG53’s role in the development of type 2 diabetes mellitus.ObjectiveThis study aims
Externí odkaz:
https://doaj.org/article/ff609bc444c74d33b75fbf793b339dd4
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 4, Pp 377-384 (2024)
Objective To explore the expression of USP9X in platelets and its effect on platelet function. Methods The expression of USP9X in human and mouse was evaluated by PCR and Western blot. Platelets from young and old mice were separated and prepared, an
Externí odkaz:
https://doaj.org/article/24c8fcdad83d400c8a3f609573b4022b
Autor:
Bingqiang Zhang, Wenyi Wang, Yu Song, Huixian Chen, Xinxin Lin, Jingjing Chen, Ying Chen, Jinfang Huang, Desen Li, Shuisheng Wu
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1318 (2024)
Background: Invasion is an important characteristic of the malignancy of glioblastoma (GBM) and a significant prognostic factor. Sempervirine (SPV), a yohimbine-type alkaloid, has been proven to inhibit GBM cells proliferation in previous research an
Externí odkaz:
https://doaj.org/article/33bf7123ec7a42b6b43e83c5dcf3899b
Autor:
Mariana Teixeira Rodrigues, Ana Paula Picaro Michelli, Gustavo Felisola Caso, Paloma Ramos de Oliveira, Dorival Mendes Rodrigues-Junior, Mirian Galliote Morale, Joel Machado Júnior, Karina Ramalho Bortoluci, Rodrigo Esaki Tamura, Tamiris Reissa Cipriano da Silva, Cristiano Raminelli, Eric Chau, Biana Godin, Jamile Calil-Silveira, Ileana G. Sanchez Rubio
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1687 (2023)
Anaplastic thyroid cancer (ATC) is an aggressive form of thyroid cancer (TC), accounting for 50% of total TC-related deaths. Although therapeutic approaches against TC have improved in recent years, the survival rate remains low, and severe adverse e
Externí odkaz:
https://doaj.org/article/a71652dc442f4d3a9f88edb218ec1cd7
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