Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Akt Wann"'
Autor:
CL Thompson, JCT Plant, AKT Wann, CL Bishop, P Novak, HM Mitchison, PL Beales, JP Chapple, MM Knight
Publikováno v:
European Cells & Materials, Vol 34, Pp 128-141 (2017)
Tissue engineering-based therapies targeting cartilage diseases, such as osteoarthritis, require in vitro expansion of articular chondrocytes. A major obstacle for these therapies is the dedifferentiation and loss of phenotype accompanying chondrocyt
Externí odkaz:
https://doaj.org/article/e1cb43698aa14005806ecaa93e9797cc
Autor:
Martin M. Knight, CA Poole, CJ Haycraft, Akt Wann, Cynthia G. Jensen, Susan R. McGlashan, N Zuo
Publikováno v:
Cilia, Vol 1, Iss Suppl 1, p P59 (2012)
Cilia
Cilia
In several cell types fluid-flow deflection of primary cilia initiates a mechanotransduction pathway via polycystin 1 and 2 (PC1/2). In articular cartilage the chondrocyte primary cilium extends into cartilage matrix. Mechanical signals including com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6817dbc077a42da48e8d423283a6a7dc
https://doi.org/10.1186/2046-2530-1-s1-p59
https://doi.org/10.1186/2046-2530-1-s1-p59
Autor:
Akt Wann, Martin M. Knight
Publikováno v:
Cilia
The assembly and maintenance of the primary cilium is managed, in part, by intraflagellar transport (IFT). Many diseases comprise an inflammatory component, often associated with elevated cytokine concentrations. Here we test the hypothesis that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580451c31ce7cbcafb1e832d6b13e5b1
https://doi.org/10.1186/2046-2530-1-s1-p60
https://doi.org/10.1186/2046-2530-1-s1-p60
Publikováno v:
Osteoarthritis and Cartilage. 20:S241-S242
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272b9872477bd5d912c413870384e535
https://doi.org/10.1016/j.joca.2012.02.399
https://doi.org/10.1016/j.joca.2012.02.399
Autor:
Coveney CR; University of Oxford, Oxford, UK.; Peabody Museum, Cambridge, Massachusetts., Zhu L; University of Oxford, Oxford, UK., Miotla-Zarebska J; University of Oxford, Oxford, UK., Stott B; University of Oxford, Oxford, UK., Parisi I; University of Oxford, Oxford, UK., Batchelor V; University of Oxford, Oxford, UK., Duarte C; University of Oxford, Oxford, UK., Chang E; University of Oxford, Oxford, UK., McSorley E; University of Oxford, Oxford, UK., Vincent TL; University of Oxford, Oxford, UK., Wann AKT
Publikováno v:
Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2022 Jan; Vol. 74 (1), pp. 49-59. Date of Electronic Publication: 2021 Dec 16.
Autor:
Mc Fie M; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK.; School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, UK., Koneva L; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Collins I; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Coveney CR; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Clube AM; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Chanalaris A; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Vincent TL; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Bezbradica JS; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Sansom SN; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK., Wann AKT; Kennedy Institute of Rheumatology Research, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford OX3 7FY, UK angus.wann@kennedy.ox.ac.uk.
Publikováno v:
Journal of cell science [J Cell Sci] 2020 Jul 08; Vol. 133 (13). Date of Electronic Publication: 2020 Jul 08.
Autor:
Collins I; Centre for OA Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7FY, UK., Wann AKT; Centre for OA Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7FY, UK.
Publikováno v:
Cells [Cells] 2020 Jan 23; Vol. 9 (2). Date of Electronic Publication: 2020 Jan 23.
Autor:
Fu S; Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK. Electronic address: s.fu@qmul.ac.uk., Thompson CL; Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK. Electronic address: Clare.l.thompson@qmul.ac.uk., Ali A; Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK. Electronic address: ahmed.ali1908@gmail.com., Wang W; Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK. Electronic address: wen.wang@qmul.ac.uk., Chapple JP; Department of Endocrinology, William Harvey Research Centre, Queen Mary University of London, UK. Electronic address: j.p.chapple@qmul.ac.uk., Mitchison HM; Institute of Child Health, University College of London, UK. Electronic address: h.mitchison@ucl.ac.uk., Beales PL; Institute of Child Health, University College of London, UK. Electronic address: p.beales@ucl.ac.uk., Wann AKT; Kennedy Institute of Rheumatology, University of Oxford, UK. Electronic address: angus.wann@kennedy.ox.ac.uk., Knight MM; Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK. Electronic address: m.m.knight@qmul.ac.uk.
Publikováno v:
Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2019 Jul; Vol. 27 (7), pp. 1064-1074. Date of Electronic Publication: 2019 Mar 25.
Autor:
Vincent TL; Arthritis Research UK Centre for OA Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Wann AKT; Arthritis Research UK Centre for OA Pathogenesis, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Publikováno v:
The Journal of physiology [J Physiol] 2019 Mar; Vol. 597 (5), pp. 1271-1281. Date of Electronic Publication: 2018 Jul 29.
Autor:
Coveney CR; Arthritis Research UK Centre for Osteoarthritis Pathogenesis, Kennedy Institute, Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Collins I; Arthritis Research UK Centre for Osteoarthritis Pathogenesis, Kennedy Institute, Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Mc Fie M; Arthritis Research UK Centre for Osteoarthritis Pathogenesis, Kennedy Institute, Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Chanalaris A; Arthritis Research UK Centre for Osteoarthritis Pathogenesis, Kennedy Institute, Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom., Yamamoto K; Arthritis Research UK Centre for Osteoarthritis Pathogenesis, Kennedy Institute, Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom., Wann AKT; Arthritis Research UK Centre for Osteoarthritis Pathogenesis, Kennedy Institute, Nuffield Department for Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2018 Jun 19, pp. fj201800334. Date of Electronic Publication: 2018 Jun 19.