Zobrazeno 1 - 10
of 1 279
pro vyhledávání: '"Aksimentiev, A."'
Autor:
Zheng, Fei, Suma, Antonio, Maffeo, Christopher, Chen, Kaikai, Alawami, Mohammed, Sha, Jingjie, Aksimentiev, Aleksei, Micheletti, Cristian, Keyser, Ulrich F
The transport of DNA polymers through nanoscale pores is central to many biological processes, from bacterial gene exchange to viral infection. In single-molecule nanopore sensing, the detection of nucleic acid and protein analytes relies on the pass
Externí odkaz:
http://arxiv.org/abs/2407.16290
In solution, DNA is a highly charged macromolecule which bears a unit of negative charge on each phosphate of its sugar-phosphate backbone. Although partially compensated by counterions adsorbed at or condensed near it, DNA still produces a substanti
Externí odkaz:
http://arxiv.org/abs/2403.04949
Autor:
Tong Wang, Kush Coshic, Mohsen Badiee, Maranda R. McDonald, Aleksei Aksimentiev, Lois Pollack, Anthony K. L. Leung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Poly(ADP-ribose) (PAR), a non-canonical nucleic acid, is essential for DNA/RNA metabolism and protein condensation, and its dysregulation is linked to cancer and neurodegeneration. However, key structural insights into PAR’s functions rema
Externí odkaz:
https://doaj.org/article/d64792a0269a42c181b4da287b581609
Autor:
Xiaoming Liu, Fengyu Liu, Hemani Chhabra, Christopher Maffeo, Zhuo Chen, Qiang Huang, Aleksei Aksimentiev, Tatsuo Arai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Synthetic membrane nanopores made of DNA are promising systems to sense and control molecular transport in biosensing, sequencing, and synthetic cells. Lumen-tunable nanopore like the natural ion channels and systematically increasing the lu
Externí odkaz:
https://doaj.org/article/1c4e2d5978294b4382c92c2969057750
Autor:
Chalmers C. Chau, Christopher M. Maffeo, Aleksei Aksimentiev, Sheena E. Radford, Eric W. Hewitt, Paolo Actis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Controlled manipulation of cultured cells by delivery of exogenous macromolecules is a cornerstone of experimental biology. Here we describe a platform that uses nanopipettes to deliver defined numbers of macromolecules into cultured cell li
Externí odkaz:
https://doaj.org/article/3608c7ce0c4946648711d04cca233e42
Autor:
Shi, Xin, Pumm, Anna-Katharina, Maffeo, Christopher, Kohler, Fabian, Feigl, Elija, Zhao, Wenxuan, Verschueren, Daniel, Golestanian, Ramin, Aksimentiev, Aleksei, Dietz, Hendrik, Dekker, Cees
Rotary motors play key roles in energy transduction, from macroscale windmills to nanoscale turbines such as ATP synthase in cells. Despite our capabilities to construct engines at many scales, developing functional synthetic turbines at the nanoscal
Externí odkaz:
http://arxiv.org/abs/2206.06612
Autor:
Tong Wang, Kush Coshic, Mohsen Badiee, Maranda R. McDonald, Aleksei Aksimentiev, Lois Pollack, Anthony K. L. Leung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/fc9a7280af254c76a7b6ee8807993b1a
Autor:
Jingqian Liu, Aleksei Aksimentiev
Publikováno v:
ACS Nanoscience Au, Vol 4, Iss 1, Pp 21-29 (2023)
Externí odkaz:
https://doaj.org/article/471ad76ba0e340238506a5fdfecd3ad0
Publikováno v:
Physical Review X, Vol 14, Iss 3, p 031042 (2024)
In solution, DNA, the “most important molecule of life,” is a highly charged macromolecule that bears a unit of negative charge on each phosphate of its sugar-phosphate backbone. Although partially compensated by counterions (cations of the solut
Externí odkaz:
https://doaj.org/article/7a9a0993fcc448819858bb4d9f4fe5f2
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