Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Akshiv Malhotra"'
Autor:
Hirofumi Yoshino, Guowei Yin, Risa Kawaguchi, Konstantin I Popov, Brenda Temple, Mika Sasaki, Satoshi Kofuji, Kara Wolfe, Kaori Kofuji, Koichi Okumura, Jaskirat Randhawa, Akshiv Malhotra, Nazanin Majd, Yoshiki Ikeda, Hiroko Shimada, Emily Rose Kahoud, Sasson Haviv, Shigeki Iwase, John M Asara, Sharon L Campbell, Atsuo T Sasaki
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224443 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0219436.].
Externí odkaz:
https://doaj.org/article/1d7864211ab34053990ab62a11907bc2
Autor:
Hirofumi Yoshino, Guowei Yin, Risa Kawaguchi, Konstantin I Popov, Brenda Temple, Mika Sasaki, Satoshi Kofuji, Kara Wolfe, Kaori Kofuji, Koichi Okumura, Jaskirat Randhawa, Akshiv Malhotra, Nazanin Majd, Yoshiki Ikeda, Hiroko Shimada, Emily Rose Kahoud, Sasson Haviv, Shigeki Iwase, John M Asara, Sharon L Campbell, Atsuo T Sasaki
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0219436 (2019)
RAS is the founding member of a superfamily of GTPases and regulates signaling pathways involved in cellular growth control. While recent studies have shown that the activation state of RAS can be controlled by lysine ubiquitylation and acetylation,
Externí odkaz:
https://doaj.org/article/537860e2dcb945cb871eddc96579b02f
Autor:
Ingrid Grummt, Sergey Mareninov, Holger Bierhoff, Paul S. Mischel, Hiroko Shimada, Lionel M.L. Chow, Nazanin Majd, Makoto Suematsu, Greg Lucey, Alexander Otto Eberhardt, Maya Asano, Yuki Ban, Kaori Kofuji, Eric P. Smith, Eric C. Holland, Noriaki Minami, Ralph J. DeBerardinis, Daisuke Yamashita, Ichiro Nakano, Kazutaka Sumita, Yoshiki Ikeda, Hirofumi Yoshino, Yuki Sugiura, Robert Bachoo, Lisa Lange, Akshiv Malhotra, Mika Sasaki, Risa Kawaguchi, Yonehiro Kanemura, Akiyoshi Hirayama, Annmarie Ramkissoon, William H. Yong, Masaru Mori, Trisha Wise-Draper, Tomoyoshi Soga, Dimitrios Anastasiou, Jumpei Terakawa, Juri Kiyokawa, Tatsuya Ozawa, Hiroaki Wakimoto, Kara Wolfe, Atsuo T. Sasaki, Nobuyuki Onishi, Satoshi Kofuji, Satsuki Ikeda, Craig Horbinski, Takiko Daikoku, Koichi Okumura, Mikako Warren, Shin Morioka, Hideyuki Saya, Naoya Sakamoto, Shuji Kitahara, Oltea Sampetrean, Wataru Yasui, Tomoyuki Mashimo, Victoria L. Flanary
Publikováno v:
Nature cell biology
In many cancers, high proliferation rates correlate with elevation of rRNA and tRNA levels, and nucleolar hypertrophy. However, the underlying mechanisms linking increased nucleolar transcription and tumorigenesis are only minimally understood. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86435a34890bf1b14f492b8043fe3bc0
https://doi.org/10.1038/s41556-019-0363-9
https://doi.org/10.1038/s41556-019-0363-9
Autor:
Konstantin I. Popov, Guowei Yin, Kara Wolfe, Sharon L. Campbell, Sasson Haviv, Risa Kawaguchi, Atsuo T. Sasaki, Satoshi Kofuji, Shigeki Iwase, Emily Rose Kahoud, Brenda Temple, Hiroko Shimada, Hirofumi Yoshino, John M. Asara, Yoshiki Ikeda, Nazanin Majd, Mika Sasaki, Kaori Kofuji, Koichi Okumura, Akshiv Malhotra, Jaskirat Randhawa
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224443 (2019)
PLoS ONE
PLoS ONE
RAS is the founding member of a superfamily of GTPases and regulates signaling pathways involved in cellular growth control. While recent studies have shown that the activation state of RAS can be controlled by lysine ubiquitylation and acetylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c012a68e7fe6cc905141a81c66384f
https://doaj.org/article/1d7864211ab34053990ab62a11907bc2
https://doaj.org/article/1d7864211ab34053990ab62a11907bc2
Autor:
Akshiv Malhotra, Guowei Yin, Emily Rose Kahoud, Jaskirat Randhawa, Konstantin I. Popov, Shigeki Iwase, Kara Wolfe, Nazanin Majd, Risa Kawaguchi, Yoshiki Ikeda, Hirofumi Yoshino, Hiroko Shimada, Kaori Kofuji, Sharon L. Campbell, Sasson Haviv, Mika Sasaki, John M. Asara, Atsuo T. Sasaki, Koichi Okumura, Satoshi Kofuji, Brenda Temple
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0219436 (2019)
PLoS ONE, Vol 14, Iss 8, p e0219436 (2019)
RAS is the founding member of a superfamily of GTPases and regulates signaling pathways involved in cellular growth control. While recent studies have shown that the activation state of RAS can be controlled by lysine ubiquitylation and acetylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924518952fa3c740c3f030b9226b3118
https://doi.org/10.1371/journal.pone.0219436
https://doi.org/10.1371/journal.pone.0219436
CBIO-12. GTP METABOLIC SWITCH LEADS TO NUCLEOLAR TRANSFORMATION AND MALIGNANT GROWTH OF GLIOBLASTOMA
Autor:
Nobuyuki Onishi, Craig Horbinski, Tomoyoshi Soga, Lionel M.L. Chow, Ingrid Grummt, Jumpei Terakawa, Kazutaka Sumita, Hideyuki Saya, Hiroaki Wakimoto, Kara Wolfe, Paul S. Mischel, Akshiv Malhotra, Akiyoshi Hirayama, Dimitrios Anastasiou, Kofuji Satoshi, Holger Bierhoff, Wataru Yasui, Kaori Kofuji, Nazanin Majd, Risa Kawaguchi, Naoya Sakamoto, Trisha Wise-Draper, Annmarie Ramkissoon, Eric C. Holland, Tatsuya Ozawa, Atsuo T. Sasaki, Takiko Daikoku, Koichi Okumura, Mikako Warren, Masaru Mori, Hirofumi Yoshino, Mika Sasaki
Publikováno v:
Neuro-Oncology. 19:vi35-vi35
Nucleolar mass is frequently increased in malignant cells, pointing to a prominent role for aberrant rRNA transcription in highly anabolic cells. ATP and GTP, fundamental energy currencies and building blocks for DNA and RNA, are synthesized by the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303fa9addbd3e3bc984709ba17df2b2d
https://doi.org/10.1093/neuonc/nox168.134
https://doi.org/10.1093/neuonc/nox168.134
Publikováno v:
American journal of clinical oncology. 39(3)
Objectives The aim of this study was to compare weekly (q1w), 2 weekly (q2w), and 3 weekly (q3w) regimens of docetaxel in metastatic castration-resistant prostate cancer (CRPC). Materials and methods We retrospectively studied patients treated with q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e66b7cb4ceb6089170741ae9d59b09
https://pubmed.ncbi.nlm.nih.gov/24662265
https://pubmed.ncbi.nlm.nih.gov/24662265
Autor:
Atsuo T. Sasaki, Satoshi Kofuji, Koichi Okumura, Osamu Ogawa, Jaskirat Randhawa, Hirofumi Yoshino, Toshinari Yamasaki, Kara Finley, Shinsuke Shibuya, Trisha Wise-Draper, Takashi Kobayashi, Nazanin Majd, Akshiv Malhotra
Publikováno v:
Journal of Clinical Oncology. 34:e16107-e16107
e16107Background: Identification of altered metabolic pathways in metastatic renal cell carcinoma (RCC) has the potential to aid in the development of diagnosis and targeted therapies. While altera...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1b96effe4ac937ad27a3961cfea74ee
https://doi.org/10.1200/jco.2016.34.15_suppl.e16107
https://doi.org/10.1200/jco.2016.34.15_suppl.e16107
Autor:
Ady Kendler, Yair M. Gozal, Richard Curry, Kazutaka Sumita, Biplab Dasgupta, Trisha Wise, Steven L. Gogela, Annmarie Ramkissoon, Luke Pater, Hirofumi Yoshino, Craig Horbinski, Atsuo T. Sasaki, Satoshi Kofuji, Mikako Warren, Lionel M.L. Chow, Akshiv Malhotra, Akiyoshi Hirayama, Ronald E. Warnick, Tomoyoshi Soga, Hiroaki Wakimoto
Publikováno v:
Neuro-Oncology. 17:v62.4-v62
Identification of altered metabolic pathways in glioma, compared to primary glial tissue, has the potential to aid in the development of diagnosis and targeted therapies for glioma, and would increase our understanding of the malignant nature of glio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cd4703c67b3a51547c3ba8e33e5778
https://doi.org/10.1093/neuonc/nov209.37
https://doi.org/10.1093/neuonc/nov209.37
Publikováno v:
Oncolytic Virotherapy
Head and neck cancer (HNC) is the sixth most common malignancy worldwide. Despite recent advancements in surgical, chemotherapy, and radiation treatments, HNC remains a highly morbid and fatal disease. Unlike many other cancers, local control rather
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db558caf554ba83c51c0957506f7325
https://doi.org/10.2147/ov.s54503
https://doi.org/10.2147/ov.s54503