Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Akshaya, Tatke"'
Autor:
Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Bhavik Soneta, Bharathi Avula, Soumyajit Majumdar
Publikováno v:
Pharmaceutics, Vol 11, Iss 4, p 158 (2019)
Delivering an effective drug load to the posterior section of the ocular tissues, while using a non-invasive technique, has always been a challenge. In this regard, the goal of the present study was to develop sustained release triamcinolone acetonid
Externí odkaz:
https://doaj.org/article/2a97b6b6cbf0428d9a729ceb11690214
Autor:
Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Sai Prachetan Balguri, Bharathi Avula, Monica M. Jablonski, Soumyajit Majumdar
Publikováno v:
Nanomaterials, Vol 9, Iss 1, p 33 (2018)
Triamcinolone acetonide (TA), an intermediate acting corticosteroid, is used in the treatment of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular edema. The objective of this investigation was to prepare TA-loa
Externí odkaz:
https://doaj.org/article/c0ed33f523874c88bdc834714720de2f
Autor:
Erin, Leigh Wood, Akshaya, Tatke, Alex, Viehmann, Melika, Ashtiani, Richard L, Friedman, Michael, Kopcha, Adam C, Fisher
Publikováno v:
International Journal of Pharmaceutics. 625:122119
An international sampling study yielded 69 samples of extended-release prescription pharmaceuticals for legal sale in the U.S. Samples included 29 lots of innovator and 40 lots of generic solid oral extended-release drugs manufactured at 16 different
Autor:
Monica M. Jablonski, Mohamed M. Ibrahim, Sai Prachetan Balguri, Karthik Yadav Janga, Doaa Nabih Maria, Soumyajit Majumdar, Narendar Dudhipala, Akshaya Tatke
Publikováno v:
J Pharmacol Exp Ther
Short precorneal residence time and poor transocular membrane permeability are the major challenges associated with topical ocular drug delivery. In the present research, the efficiency of the electrolyte-triggered sol-to-gel-forming system of natamy
Autor:
Monica M. Jablonski, Akshaya Tatke, XiangDi Wang, Bharathi Avula, Karthik Yadav Janga, Ikhlas A. Khan, Soumyajit Majumdar
Publikováno v:
AAPS PharmSciTech
The current research was undertaken to determine the existence and magnitude of P-glycoprotein (P-gp) expression on the blood-ocular barriers by studying the ocular penetration of loperamide, a specific P-gp substrate, in P-gp (Mdr1a) knock-out (KO)
Autor:
Sai Prachetan Balguri, Akshaya Tatke, Prakash Bhagav, Karthik Yadav Janga, Goutham R. Adelli, Soumyajit Majumdar
Publikováno v:
Journal of Pharmaceutical Sciences. 106:3515-3523
The objective of the present study was to evaluate the utility of melt-cast, topical, ocular inserts for delivery of drugs with different physicochemical properties. The model drugs tested include indomethacin (IN), ciprofloxacin hydrochloride, and p
Autor:
Monica M. Jablonski, Sai Prachetan Balguri, Soumyajit Majumdar, Bharathi Avula, Narendar Dudhipala, Akshaya Tatke, Karthik Yadav Janga
Publikováno v:
Nanomaterials
Nanomaterials, Vol 9, Iss 1, p 33 (2018)
Volume 9
Issue 1
Nanomaterials, Vol 9, Iss 1, p 33 (2018)
Volume 9
Issue 1
Triamcinolone acetonide (TA), an intermediate acting corticosteroid, is used in the treatment of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular edema. The objective of this investigation was to prepare TA-loa
Publikováno v:
Expert Opin Drug Deliv
INTRODUCTION: Ocular drug delivery is presented with many challenges, taking into account the distinctive structure of the eye. The prodrug approach has been, and is being, employed to overcome such barriers for some drug molecules, utilizing a chemi
Autor:
Soumyajit Majumdar, Surya P Lamichanne, Karthik Yadav Janga, Mohamed M. Ibrahim, Sai Prachetan Balguri, Akshaya Tatke, Doaa Nabih Maria, Monica M. Jablonski
Publikováno v:
Artificial cells, nanomedicine, and biotechnology. 46(sup1)
Delivery of therapeutic molecules into the deeper ocular compartments is mainly hampered by short precorneal residence and limited transmembrane permeability of topically administered drugs. Hence, the current study was undertaken to fabricate the io
Autor:
Soumyajit Majumdar, Bharathi Avula, XiangDi Wang, Ikhlas A. Khan, Monica M. Jablonski, Surya P. Lamichhane, Surabhi Shukla, Akshaya Tatke, Karthik Yadav Janga
Publikováno v:
J Pharm Sci
Effective drug delivery to the deeper ocular tissues remains an unresolved conundrum mainly due to the expression of multidrug resistance (MDR) efflux proteins, beside tight junction proteins, in the blood ocular barriers (BOB). Hence, the purpose of