Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Akshay A D'Cruz"'
Autor:
Joan Teyra, Abdellali Kelil, Shobhit Jain, Mohamed Helmy, Raghav Jajodia, Yogesh Hooda, Jun Gu, Akshay A D’Cruz, Sandra E Nicholson, Jinrong Min, Marius Sudol, Philip M Kim, Gary D Bader, Sachdev S Sidhu
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp 1-15 (2020)
Abstract Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction partners. Here, we used large‐scale peptide‐phage display methods to derive opti
Externí odkaz:
https://doaj.org/article/d19aa4af6b674dc78769d9a4bc13168c
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2523
Neutrophil extracellular traps (NETs) are networks of chromatin and microbicidal proteins released by neutrophils in response to infection and tissue damage. Although classically viewed as a discrete biochemical and cellular process in neutrophils, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f18f1153b242ed8db992d1c1734d7c73
https://pubmed.ncbi.nlm.nih.gov/35759202
https://pubmed.ncbi.nlm.nih.gov/35759202
Publikováno v:
Methods in Molecular Biology ISBN: 9781071624487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9731bc1e8615dd3ab64373e47632600a
https://doi.org/10.1007/978-1-0716-2449-4_16
https://doi.org/10.1007/978-1-0716-2449-4_16
Autor:
Jinrong Min, Sandra E. Nicholson, Joan Teyra, Sachdev S. Sidhu, Abdellali Kelil, Yogesh Hooda, Shobhit Jain, Gary D. Bader, Mohamed Helmy, Akshay A. D’Cruz, Marius Sudol, Philip M. Kim, Jun Gu, Raghav Jajodia
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Molecular Systems Biology
Molecular Systems Biology
Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction partners. Here, we used large‐scale peptide‐phage display methods to derive optimal ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72daa4f4cb48b6952a0698d642540291
https://doi.org/10.15252/msb.20199310
https://doi.org/10.15252/msb.20199310
Autor:
David J. Segal, Kurt Lackovic, David C.S. Huang, Joanne A. O’Donnell, Ben A. Croker, Kate McArthur, Andrew F. Wilks, Cameron J. Nowell, Christopher J. Burns, Akshay A. D’Cruz, Motti Gerlic
Publikováno v:
Oncotarget
Neutropenia represents one of the major dose-limiting toxicities of many current cancer therapies. To circumvent the off-target effects of cytotoxic chemotherapeutics, kinase inhibitors are increasingly being used as an adjunct therapy to target leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d09649202994343b66166c18f356221
https://doi.org/10.18632/oncotarget.19678
https://doi.org/10.18632/oncotarget.19678
Autor:
Paul R Lakin, Mary Speir, Heather Patsiouras, Ben A. Croker, Roman Othmar Braun, Shu Wang, Rowena S. Lewis, Razq Hakem, Akshay A. D’Cruz, Nathan E. Lewis, Andrew W. Roberts, Kate E. Lawlor, Anca I. Stoica, Louise H. Cengia, Isaac Shamie, Joanne A. O’Donnell, Edie Weller, Inbar Shlomovitz, Motti Gerlic, Meghan Bliss-Moreau, Jeffrey J. Babon, Lorraine A. O'Reilly, Alyce A. Chen, Cameron J. Nowell, Michelle A. Kelliher
Publikováno v:
Nature immunology
Ptpn6 is a cytoplasmic phosphatase that functions to prevent autoimmune and interleukin-1 (IL-1) receptor-dependent, caspase-1-independent inflammatory disease. Conditional deletion of Ptpn6 in neutrophils (Ptpn6∆PMN) is sufficient to initiate IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f740d82258ffc5cdd45e650ba2c7b01
https://pubmed.ncbi.nlm.nih.gov/31819256
https://pubmed.ncbi.nlm.nih.gov/31819256
Publikováno v:
Immunology & Cell Biology. 95:146-151
Immunological responses activated by pathogen recognition come in many guises. The proliferation, differentiation and recruitment of immune cells, and the production of inflammatory cytokines and chemokines are central to lifelong immunity. Cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e95176726d7ba1607b443bf394e151
https://doi.org/10.1038/icb.2016.113
https://doi.org/10.1038/icb.2016.113
Autor:
Mathilde Gavillet, Shu Wang, Ben A. Croker, David A. Williams, Michelle A. Kelliher, Meghan Bliss-Moreau, Sylvia Dietrich, Manolis Pasparakis, Alyce A. Chen, Akshay A. D’Cruz, Mary Speir, James E Vince, Arshed Al-Obeidi, Kate E. Lawlor, Maria Ericsson, Razq Hakem
Publikováno v:
Science signaling. 11(546)
Neutrophil extracellular trap (NET) formation can generate short-term, functional anucleate cytoplasts and trigger loss of cell viability. We demonstrated that the necroptotic cell death effector mixed lineage kinase domain–like (MLKL) translocated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc522e88c1e93eee920f2476cb29cd7
https://pubmed.ncbi.nlm.nih.gov/30181240
https://pubmed.ncbi.nlm.nih.gov/30181240
Autor:
Ben A Croker, Mary Speir, Cameron J Nowell, Alyce A Chen, Joanne A O’Donnell, Akshay A D’Cruz, Meghan Bliss-Moreau, Shu Wang, Michelle A Kelliher, Razq Hakem, Motti Gerlic
Publikováno v:
The Journal of Immunology. 202:59.4-59.4
Neutrophilic dermatoses are a group of inflammatory skin disorders characterized by sterile infiltrates of neutrophils. These syndromes include pyoderma gangrenosum (PG) and Sweet’s syndrome (SS), and they are associated with an increased incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b46d9becf7a6bbecde098b27cfaee049
https://doi.org/10.4049/jimmunol.202.supp.59.4
https://doi.org/10.4049/jimmunol.202.supp.59.4