VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic Injury

Autor: Schlüter, Annabelle, Aksan, Bahar, Diem, Ricarda, Fairless, Richard, Mauceri, Daniela

Publikováno v: In Molecular Therapy - Methods & Clinical Development 12 June 2020 17:281-299

Cyclase-associated protein 2 dimerization regulates cofilin in synaptic plasticity and Alzheimer's disease

Autor: Pelucchi, Silvia, Vandermeulen, Lina, Pizzamiglio, Lara, Aksan, Bahar, Yan, Jing, Konietzny, Anja, Bonomi, Elisa, Borroni, Barbara, Padovani, Alessandro, Rust, Marco B, Di Marino, Daniele, Mikhaylova, Marina, Mauceri, Daniela, Antonucci, Flavia, Edefonti, Valeria, Gardoni, Fabrizio, Di Luca, Monica, Marcello, Elena

Publikováno v: Brain Communications

Regulation of actin cytoskeleton dynamics in dendritic spines is crucial for learning and memory formation. Hence, defects in the actin cytoskeleton pathways are a biological trait of several brain diseases, including Alzheimer's disease. Here, we de

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http://europepmc.org/articles/PMC7566557

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VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic Injury.

Autor: Schlüter A; Department of Neurobiology, Interdisciplinary Center for Neurosciences, Heidelberg University, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany., Aksan B; Department of Neurobiology, Interdisciplinary Center for Neurosciences, Heidelberg University, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany., Diem R; Department of Neurology, University Clinic Heidelberg, Im Neuenheimer Feld 368, 69120 Heidelberg, Germany.; CCU Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany., Fairless R; Department of Neurology, University Clinic Heidelberg, Im Neuenheimer Feld 368, 69120 Heidelberg, Germany.; CCU Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany., Mauceri D; Department of Neurobiology, Interdisciplinary Center for Neurosciences, Heidelberg University, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2019 Dec 25; Vol. 17, pp. 281-299. Date of Electronic Publication: 2019 Dec 25 (Print Publication: 2020).