Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Aksam Merched"'
Publikováno v:
Cells
Cells, 2022, 11 (24), pp.4132. ⟨10.3390/cells11244132⟩
Cells, 2022, 11 (24), pp.4132. ⟨10.3390/cells11244132⟩
International audience; Metabolic rewiring and defective immune responses are considered to be the main driving forces sustaining cell growth and oncogenesis in many cancers. The atypical enzyme, proprotein convertase subtilisin/kexin type 9 (PCSK9),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148ef781fdb082a9e1cdb053a1b5234a
https://www.hal.inserm.fr/inserm-03920559/file/cells-11-04132.pdf
https://www.hal.inserm.fr/inserm-03920559/file/cells-11-04132.pdf
Autor:
S. Ducassou, Christophe Grosset, Patrick Auguste, Sarah Lesjean, Béatrice Turcq, Aksam Merched, Philippe Veschambre, Véronique Trézéguet
Publikováno v:
Bulletin du Cancer
Bulletin du Cancer, 2020, ⟨10.1016/j.bulcan.2020.07.012⟩
Bulletin du Cancer, 2020, ⟨10.1016/j.bulcan.2020.07.012⟩
International audience; Contexte scientifique: Malgré des avancées majeures en oncologie depuis vingt ans, 20 % des enfants et adolescents atteints d'un cancer en France décèdent de leur maladie et parmi ceux qui survivent, beaucoup gardent penda
Publikováno v:
Cells
Cells, Vol 10, Iss 3469, p 3469 (2021)
Cells, 2021, 10 (12), pp.3469. ⟨10.3390/cells10123469⟩
Cells, Vol 10, Iss 3469, p 3469 (2021)
Cells, 2021, 10 (12), pp.3469. ⟨10.3390/cells10123469⟩
International audience; Metabolic rewiring in tumor cells is a major hallmark of oncogenesis. Some of the oncometabolites drive suppressive and tolerogenic signals from the immune system, which becomes complicit to the advent and the survival of neop
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
Biochemistry, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
Biochemistry, American Chemical Society, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
Biochemistry, 2020, 59 (41), pp.3951-3964. ⟨10.1021/acs.biochem.0c00477⟩
International audience; Cancer cells are highly dependent on different metabolic pathways for sustaining their survival, growth, and proliferation. Lipid metabolism not only provides the energetic needs of the cells but also provides the raw material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529e77c58f4481749fb0c3d96e128e16
https://hal.archives-ouvertes.fr/hal-03373099/document
https://hal.archives-ouvertes.fr/hal-03373099/document
Publikováno v:
Biochemistry
Biochemistry, American Chemical Society, 2020, 59 (37), pp.3393-3400. ⟨10.1021/acs.biochem.0c00476⟩
Biochemistry, American Chemical Society, 2020, 59 (37), pp.3393-3400. ⟨10.1021/acs.biochem.0c00476⟩
International audience; HMG-CoA reductase inhibitors (known as statins) are commonly prescribed worldwide for the management of coronary heart disease and the underlying dyslipidemia. This class of drugs has been shown to infer a significant decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4dd6113b09a3b4c5afaba5ff330db9
https://hal.archives-ouvertes.fr/hal-03373090/file/Alipour_al.pdf
https://hal.archives-ouvertes.fr/hal-03373090/file/Alipour_al.pdf
Autor:
Bassam Badran, Redouane Rouas, Philippe Martiat, Arsène Burny, Luc Vanhamme, Rim ElDirani, Eva Hamade, Mehdi Najar, Makram Merimi, Malak Alannan, Aksam Merched, Walid Rachidi, Philippe Lewalle, Mohammad Fayyad-Kazan, Nizar Bitar, Hussein Fayyad-Kazan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb7425dbd3b27a0994b421e6459f12e
https://doi.org/10.37247/imcac.1.2020.1
https://doi.org/10.37247/imcac.1.2020.1
Publikováno v:
Biochemistry. 59:4516-4516
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2016, 30 (6), pp.2123-2134. ⟨10.1096/fj.201500131⟩
FASEB Journal, 2016, 30 (6), pp.2123-2134. ⟨10.1096/fj.201500131⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2016, 30 (6), pp.2123-2134. ⟨10.1096/fj.201500131⟩
FASEB Journal, 2016, 30 (6), pp.2123-2134. ⟨10.1096/fj.201500131⟩
Higher cardiovascular morbidity in patients with a wide range of autoimmune diseases highlights the importance of autoimmunity in promoting atherosclerosis. Our purpose was to investigate the mechanisms of accelerated atherosclerosis and identified v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d31079282471aebce91fce55766749
https://www.hal.inserm.fr/inserm-01784116
https://www.hal.inserm.fr/inserm-01784116
Autor:
Jean-Benoît Corcuff, Aksam Merched
The integration of the human genome project with nutritional, genetic research, and health outcomes studies has led to the emergence of nutrigenetics and nutrigenomics. These disciplines investigate in a systematic fashion the effect of genetic makeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f764a077ae2febfacd4e5ee942f37237
https://doi.org/10.1016/b978-0-12-801816-3.00003-0
https://doi.org/10.1016/b978-0-12-801816-3.00003-0
Publikováno v:
Experimental Dermatology. 26:635-636
The therapeutic hypothesis proposed by Speeckaert and van Geel in this issue (1) is based on the dramatic effects of the new drugs targeting immune privilege checkpoints (PD1/PDL, CTLA4) in current advanced melanoma therapy as major inductors of viti