Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Akosua Vilaysane"'
Autor:
Justin Chun, James R. Wright, Henry J. Duff, Paul W.M. Fedak, Daniel A. Muruve, H. Christopher Meijndert, Benjamin Gershkovich, Paul L. Beck, Nathan A. Bracey, Akosua Vilaysane
Publikováno v:
Journal of Biological Chemistry. 289:19571-19584
Nucleotide-binding domain and leucine-rich repeat containing PYD-3 (NLRP3) is a pattern recognition receptor that is implicated in the pathogenesis of inflammation and chronic diseases. Although much is known regarding the NLRP3 inflammasome that reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fef17218ed755addadee06ed8a759e
https://doi.org/10.1074/jbc.m114.550624
https://doi.org/10.1074/jbc.m114.550624
Autor:
Adriana Migliorini, Helen Liapis, Fay Munro, Murthy N. Darisipudi, Akosua Vilaysane, Yan Shi, Onkar P. Kulkarni, Khader Valli Rupanagudi, Daniel A. Muruve, Shrikant R. Mulay, Hans-Joachim Anders
Publikováno v:
Journal of Clinical Investigation. 123:236-246
Nephrocalcinosis, acute calcium oxalate (CaOx) nephropathy, and renal stone disease can lead to inflammation and subsequent renal failure, but the underlying pathological mechanisms remain elusive. Other crystallopathies, such as gout, atherosclerosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d48b767c654113e53b1fe759212da18
https://doi.org/10.1172/jci63679
https://doi.org/10.1172/jci63679
Autor:
Kiril Trpkov, Mark E. Seamone, Sharon A. Clark, Rick Chin, Wenjie Wang, Daniel A. Muruve, Yan Li, Jürg Tschopp, Simon A. Hirota, Paul L. Beck, Akosua Vilaysane, Brenda R. Hemmelgarn, Justin Chun
Publikováno v:
Journal of the American Society of Nephrology. 21:1732-1744
Inflammation significantly contributes to the progression of chronic kidney disease (CKD). Inflammasome-dependent cytokines, such as IL-1β and IL-18, play a role in CKD, but their regulation during renal injury is unknown. Here, we analyzed the proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc3b290b9e846e81e9896d3968a983c
https://doi.org/10.1681/asn.2010020143
https://doi.org/10.1681/asn.2010020143
Autor:
Sharon A. Clark, Akosua Vilaysane, Daniel A. Muruve, H. Christopher Meijndert, Virginie Pétrilli, Anne K. Zaiss, Pina Colarusso, Matthew J. Cotter, Jürg Tschopp, Robin M. Yates
Publikováno v:
The Journal of Immunology. 182:7058-7068
Adenovirus is a nonenveloped dsDNA virus that activates intracellular innate immune pathways. In vivo, adenovirus-immunized mice displayed an enhanced innate immune response and diminished virus-mediated gene delivery following challenge with the ade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38da57836e3a61feb8cbd9b1698b602d
https://doi.org/10.4049/jimmunol.0804269
https://doi.org/10.4049/jimmunol.0804269
Autor:
Sharon A. Clark, Akosua Vilaysane, Justin Chun, Henry J. Duff, Kiril Trpkov, Shirin Bonni, Gabrielle French, Wenjie Wang, Nathan A. Bracey, Xiangyu Wang, Paul L. Beck, Daniel A. Muruve
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(3)
Tubulointerstitial inflammation and fibrosis are strongly associated with the outcome of chronic kidney disease. We recently demonstrated that the NOD-like receptor, pyrin domain containing-3 (NLRP3) contributes to renal inflammation, injury, and fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5850181481801f3f7185a8d6a38caa47
https://pubmed.ncbi.nlm.nih.gov/23264657
https://pubmed.ncbi.nlm.nih.gov/23264657
Autor:
Akosua Vilaysane, Daniel A. Muruve
Publikováno v:
Seminars in immunology. 21(4)
As a component of all living cells and microbes, it is not surprising that organisms have evolved mechanisms to detect foreign or aberrant DNA and trigger an innate immune response. TLR9 is an endosomal membrane bound receptor that is widely studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deff67e3f24fcac5fb6d2aeabf006e18
https://pubmed.ncbi.nlm.nih.gov/19497760
https://pubmed.ncbi.nlm.nih.gov/19497760
Autor:
Mark E. Seamone, Olaf Gross, L. Patrick Schenck, Akosua Vilaysane, Annegret Ulke–Lemee, Daniel A. Muruve, Justin A. MacDonald, Simon A. Hirota, Yan Li, Jürg Tschopp, Paul L. Beck, Glen D. Armstrong, Mireille S. Potentier, Jeffrey Ng, Hanping Feng
Publikováno v:
Gastroenterology. 139:542-552.e3
Background & Aims Clostridium difficile –associated disease (CDAD) is the leading cause of nosocomial diarrhea in the United States. C difficile toxins TcdA and TcdB breach the intestinal barrier and trigger mucosal inflammation and intestinal dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b607db3d980fc92939a9db85075552ed
https://doi.org/10.1053/j.gastro.2010.04.005
https://doi.org/10.1053/j.gastro.2010.04.005
Publikováno v:
Frontiers in Pharmacology; 2024, p1-18, 18p
Autor:
Wu, Ziyu1,2 (AUTHOR), Li, Dan1 (AUTHOR), Tian, Dingyuan1 (AUTHOR), Liu, Xuejun1 (AUTHOR) xuejunliu2020@163.com, Wu, Zhongming1,3 (AUTHOR) xuejunliu2020@163.com
Publikováno v:
PLoS ONE. 12/14/2022, Vol. 17 Issue 12, p1-27. 27p.
Publikováno v:
Wound Repair & Regeneration. Jul/Aug2018, Vol. 26 Issue 4, pA1-A20. 20p.