Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ako Ishihara"'
Autor:
Abigail L. Lauterbach, Rachel P. Wallace, Aaron T. Alpar, Kirsten C. Refvik, Joseph W. Reda, Ako Ishihara, Taryn N. Beckman, Anna J. Slezak, Yukari Mizukami, Aslan Mansurov, Suzana Gomes, Jun Ishihara, Jeffrey A. Hubbell
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Non-healing wounds have a negative impact on quality of life and account for many cases of amputation and even early death among patients. Diabetic patients are the predominate population affected by these non-healing wounds. Despite the sig
Externí odkaz:
https://doaj.org/article/601c46ab07994fd8abb735c9a63a3160
Autor:
Abigail L. Lauterbach, Rachel P. Wallace, Aaron T. Alpar, Kirsten C. Refvik, Joseph W. Reda, Ako Ishihara, Taryn N. Beckman, Anna J. Slezak, Yukari Mizukami, Aslan Mansurov, Suzana Gomes, Jun Ishihara, Jeffrey A. Hubbell
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0ef528f3aa074bfe9c42f09a1a03979d
Autor:
Kiyomitsu Katsumata, Jun Ishihara, Kazuto Fukunaga, Ako Ishihara, Eiji Yuba, Erica Budina, Jeffrey A. Hubbell
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract Background Although disease in a majority of rheumatoid arthritis (RA) patients is often initially limited to one or a few joints, currently approved medications including anti-tumor necrosis factor-α antibody (α-TNF) are injected systemic
Externí odkaz:
https://doaj.org/article/5d877f7d012a4cd8b7a0f1b126dce533
Autor:
Jun Ishihara, Ako Ishihara, Kazuto Fukunaga, Koichi Sasaki, Michael J. V. White, Priscilla S. Briquez, Jeffrey A. Hubbell
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Laminins are important regulators of epidermal wound healing. Here, the authors show that laminins bind to multiple growth factors via their heparin-binding domains, and that incorporation of these domains into fibrin matrices increases growth factor
Externí odkaz:
https://doaj.org/article/970479756e7a4accbe4500ad2b9305a7
Autor:
Michael Laffan, Koval E. Smith, Koichi Sasaki, Jun Ishihara, Matthias P. Lutolf, Jeffrey A. Hubbell, Michael J. V. White, Yoji Tabata, Kazuto Fukunaga, Richard D. Starke, Thomas A. J. McKinnon, Ako Ishihara, Claire Peghaire, Anna M. Randi
Publikováno v:
Blood. 133:2559-2569
During wound healing, the distribution, availability, and signaling of growth factors (GFs) are orchestrated by their binding to extracellular matrix components in the wound microenvironment. Extracellular matrix proteins have been shown to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd28d846b14428547fd5c68c2070992e
https://doi.org/10.1182/blood.2019000510
https://doi.org/10.1182/blood.2019000510
Autor:
Jun Ishihara, Kiyomitsu Katsumata, Eiji Yuba, Ako Ishihara, Jeffrey A. Hubbell, Peyman Hosseinchi, Melody A. Swartz, Joseph W. Reda, Aslan Mansurov, Elyse A. Watkins, Andrew C Tremain, Ani Solanki, Aaron T. Alpar, Erica Budina, Lea Maillat, Takahiro Kageyama, Mindy Nguyen
Interleukin-4 (IL-4) suppresses the development of multiple sclerosis in a murine model of experimental autoimmune encephalomyelitis (EAE). Here, we show that, in mice with EAE, the accumulation and persistence in the lymph nodes and spleen of a syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc2c54ec773f6e2b7177fa901442dd6
http://hdl.handle.net/10044/1/83460
http://hdl.handle.net/10044/1/83460
Autor:
Tiffany M. Marchell, Ako Ishihara, Michal M. Raczy, Jun Ishihara, Jeffrey A. Hubbell, Peyman Hosseinchi, Aslan Mansurov, Melody A. Swartz, Aaron T. Alpar, Laura T. Gray, Lambert Potin, John-Michael Williford
Checkpoint-inhibitor (CPI) immunotherapy has achieved remarkable clinical success, yet its efficacy in 'immunologically cold' tumours has been modest. Interleukin-12 (IL-12) is a powerful cytokine that activates the innate and adaptive arms of the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faad1582775a7a1e09db5a5eac713d07
http://hdl.handle.net/10044/1/83774
http://hdl.handle.net/10044/1/83774
Autor:
Ako, Ishihara, Jun, Ishihara, Elyse A, Watkins, Andrew C, Tremain, Mindy, Nguyen, Ani, Solanki, Kiyomitsu, Katsumata, Aslan, Mansurov, Erica, Budina, Aaron T, Alpar, Peyman, Hosseinchi, Lea, Maillat, Joseph W, Reda, Takahiro, Kageyama, Melody A, Swartz, Eiji, Yuba, Jeffrey A, Hubbell
Publikováno v:
Nature biomedical engineering. 5(5)
Interleukin-4 (IL-4) suppresses the development of multiple sclerosis in a murine model of experimental autoimmune encephalomyelitis (EAE). Here, we show that, in mice with EAE, the accumulation and persistence in the lymph nodes and spleen of a syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68c43e02287c4911b22431ceb429eeff
https://pubmed.ncbi.nlm.nih.gov/33093659
https://pubmed.ncbi.nlm.nih.gov/33093659
Autor:
Tiffany M. Marchell, Melody A. Swartz, Ako Ishihara, Jun Ishihara, Aslan Mansurov, Jeffrey A. Hubbell, Peyman Hosseinchi, Lambert Potin, John-Michael Williford
Publikováno v:
Science Advances
Targeted delivery of CCL4 to the tumor stroma recruits CD103+ dendritic cells and enhances the efficacy of CPI immunotherapy.
Although a clinical breakthrough for cancer treatment, it remains that a minority of patients respond to checkpoint inh
Although a clinical breakthrough for cancer treatment, it remains that a minority of patients respond to checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f306b9ac7c8c2d01998b80fbeb6fe59e
https://doi.org/10.1126/sciadv.aay1357
https://doi.org/10.1126/sciadv.aay1357
Autor:
Eiji Yuba, Jeffrey A. Hubbell, Michal M. Raczy, Ako Ishihara, Jun Ishihara, Kiyomitsu Katsumata, Aslan Mansurov
Publikováno v:
Nature Reviews Rheumatology
Science Advances
Science Advances
Inflammation targeting through collagen affinity improves antibody therapeutic ability.
Enhancing the therapeutic efficacy of drugs for inflammatory diseases is of high demand. One possible approach is targeting drugs to the extracellular matrix
Enhancing the therapeutic efficacy of drugs for inflammatory diseases is of high demand. One possible approach is targeting drugs to the extracellular matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5343d0df93a728ca917a7fdf9caa06da