The effect of CYP2D6 and CYP2C9 gene polymorphisms on the efficacy and safety of the combination of tramadol and ketorolac used for postoperative pain management in patients after video laparoscopic cholecystectomy.

Autor: Muradian, Andranik Alexandrovich, Sychev, Dmitry Alekseevich, Blagovestnov, Dmitry Alekseevich, Sozaeva, Zhannet Alimovna, Akmalova, Kristina Anatolyevna, Zastrozhin, Michael Sergeevich, Kerimova, Leyla Nabievna, Koroshvili, Vadim Teymurazovich, Epifanova, Irina Alexandrovna

Publikováno v: Drug Metabolism & Personalized Therapy; Mar2022, Vol. 37 Issue 1, p27-34, 8p

The effect of CYP2D6 and CYP2C9 gene polymorphisms on the efficacy and safety of the combination of tramadol and ketorolac used for postoperative pain management in patients after video laparoscopic cholecystectomy.

Autor: Muradian AA; Department of Urgent and General Surgery, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Sychev DA; Department of Clinical Pharmacology and Therapeutics, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Blagovestnov DA; Department of Urgent and General Surgery, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Sozaeva ZA; Department of Molecular Medicine, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Akmalova KA; Department of Molecular Medicine, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Zastrozhin MS; Moscow Department of Healthcare, Moscow Research and Practical Centre on Addictions, Moscow, Russia., Kerimova LN; Department of Urgent and General Surgery, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Koroshvili VT; Department of Urgent and General Surgery, Russian Medical Academy of Continuous Professional Education, Moscow, Russia., Epifanova IA; Department of Urgent and General Surgery, Russian Medical Academy of Continuous Professional Education, Moscow, Russia.

Publikováno v: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2021 Jul 12. Date of Electronic Publication: 2021 Jul 12.