Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aklile Berhanu"'
Autor:
Catherine B. Bigger, Andrew T. Russo, Aklile Berhanu, Dennis E. Hruby, Jon Prigge, Douglas W. Grosenbach, Peter Silvera
Publikováno v:
Vaccine
Naturally occurring smallpox has been eradicated but research stocks of variola virus (VARV), the causative agent of smallpox, still exist in secure laboratories. Clandestine stores of the virus or resurrection of VARV via synthetic biology are possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3e432571b3c73936f835d82b13ce7c
https://doi.org/10.1016/j.vaccine.2019.10.049
https://doi.org/10.1016/j.vaccine.2019.10.049
Autor:
Ryan Owen, Jessica Couch, Aklile Berhanu, Jeremy J. Lim, Montserrat Carrasco-Triguero, Rong Deng, Ola Saad, Melicent C. Peck, Sharon M Rymut
Publikováno v:
Open Forum Infectious Diseases
Background DSTA4637S, a THIOMABTM antibody-antibiotic conjugate against Staphylococcus aureus, is a potential therapy for complicated S. aureus bacteremia. Single doses showed favorable safety and pharmacokinetics (PK) in healthy volunteers (HVs). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7265d7123fa992e9976c318f091aa3bf
http://europepmc.org/articles/PMC7777007
http://europepmc.org/articles/PMC7777007
Autor:
Henry F. Chambers, Nicholas Lewin-Koh, Jason B Dinoso, Carrie M. Rosenberger, Catherine A. Koss, Joanna K Chang, Alessander O Guimaraes, Melicent C. Peck, Johnny Gutierrez, Janice Kim, Min Xu, Amos Baruch, Angelo Clemenzi-Allen, Donghong Yan, Yi Cao, Aklile Berhanu
Publikováno v:
Open Forum Infectious Diseases. 6
Background Staphylococcus aureus (SA) bacteremia often requires a long treatment duration with antibiotics to prevent relapse due to the ability of SA to establish reservoirs of infection in sites such as heart and bone. These metastatic sites of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a927b6e7d4546cb85b8d13385c6f2ef6
https://doi.org/10.1093/ofid/ofz090
https://doi.org/10.1093/ofid/ofz090
Autor:
Johnny, Gutierrez, Alessander O, Guimaraes, Nicholas, Lewin-Koh, Aklile, Berhanu, Min, Xu, Yi, Cao, Janice, Kim, Donghong, Yan, Joanna K, Chang, Jason B, Dinoso, Catherine A, Koss, Angelo, Clemenzi-Allen, Henry F, Chambers, Melicent C, Peck, Amos, Baruch, Carrie M, Rosenberger
Publikováno v:
Open Forum Infectious Diseases
Background Staphylococcus aureus (SA) bacteremia often requires a long treatment duration with antibiotics to prevent relapse due to the ability of SA to establish reservoirs of infection in sites such as heart and bone. These metastatic sites of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8023473de2e089c377b6bede6083e17d
https://pubmed.ncbi.nlm.nih.gov/31024970
https://pubmed.ncbi.nlm.nih.gov/31024970
Autor:
Carrie C Rosenberger, Jeremy J. Lim, Sharon M Rymut, Nicholas Lewin-Koh, Loren G. Miller, José M. Miró, Wouter L. W. Hazenbos, Melicent C. Peck, Vance G. Fowler, Montserrat Carrasco-Triguero, Jessica Couch, Tom Chu, Aklile Berhanu
Publikováno v:
Open Forum Infectious Diseases
Background New treatment approaches for complicated Staphylococcus aureus bacteremia (SAB) are needed. DSTA4637S is a THIOMABTM antibody-antibiotic conjugate consisting of an engineered human IgG1 monoclonal antibody that binds to wall teichoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4400742316af5cff145b2d97d5424e69
https://doi.org/10.1093/ofid/ofaa439.477
https://doi.org/10.1093/ofid/ofaa439.477
Autor:
Shanthakumar R. Tyavanagimatt, Stone Melialani A C L, Kristin A. Wineinger, Eric Stavale, Pietro Scaturro, Dennis E. Hruby, Christine Schneider, Douglas W. Grosenbach, Kara B. Cardwell, Chelsea M. Byrd, Robert Jordan, Jessica M. Page, Kevin F. Jones, Ralf Bartenschlager, Aklile Berhanu, Dongcheng Dai, Chris Harver
Publikováno v:
PubMed Central
Dengue viruses (DENV) infect 50 to 100 million people worldwide per year, of which 500,000 develop severe life-threatening disease. This mosquito-borne illness is endemic in most tropical and subtropical countries and has spread significantly over th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106293438e92a61421716293edf39a57
https://doi.org/10.1128/aac.01429-12
https://doi.org/10.1128/aac.01429-12
Autor:
David S. King, Kevin F. Jones, Douglas W. Grosenbach, Robert Jordan, Dennis E. Hruby, Aklile Berhanu, Stacie Mosier, Tove' C. Bolken
Publikováno v:
Proceedings of the National Academy of Sciences. 107:838-843
The threat of smallpox as a bioweapon and the emerging threat of human monkeypox, among other poxviral diseases, highlight the need for effective poxvirus countermeasures. ST-246, which targets the F13L protein in vaccinia virus and its homologs in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aff9194dad94b762987d3497aaeddf0
https://doi.org/10.1073/pnas.0912134107
https://doi.org/10.1073/pnas.0912134107
Autor:
Shanthakumar R. Tyavanagimatt, Ying Tan, Kevin F. Jones, Douglas W. Grosenbach, Travis K. Warren, Rebecca L. Wilson, Dana L. Kirkwood-Watts, Robert Jordan, Aklile Berhanu, David S. King, Dennis E. Hruby
Publikováno v:
Vaccine. 26:933-946
The re-emerging threat of smallpox and the emerging threat of monkeypox highlight the need for effective poxvirus countermeasures. Currently approved smallpox vaccines have unacceptable safety profiles and, consequently, the general populace is no lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922fbfc21930e4b5a18d34be6edd08e6
https://doi.org/10.1016/j.vaccine.2007.11.095
https://doi.org/10.1016/j.vaccine.2007.11.095
Publikováno v:
The Journal of Immunology. 178:3400-3408
Regulatory T cells can suppress activated CD4+ and CD8+ T effector cells and may serve as an impediment to spontaneous or therapeutic type 1 antitumor immunity. In a previous study, we observed minimal therapeutic impact, but significantly enhanced T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff40496b9151c0048a59159db46d1e6
https://doi.org/10.4049/jimmunol.178.6.3400
https://doi.org/10.4049/jimmunol.178.6.3400
Autor:
Eric Stavale, Janet M. Leeds, Guang Yang, Stone Melialani A C L, Chris Harver, Douglas W. Grosenbach, Christine Schneider, Dongcheng Dai, Kevin F. Jones, Jessica M. Page, Kristin A. Wineinger, Candace Lovejoy, Robert Jordan, Kara B. Cardwell, Chelsea M. Byrd, Dennis E. Hruby, Aklile Berhanu, Kathleen P. Fuller, Shanthakumar R. Tyavanagimatt
Publikováno v:
Antimicrobial Agents and Chemotherapy
Dengue virus (DENV) is the predominant mosquito-borne viral pathogen that infects humans with an estimated 50 to 100 million infections per year worldwide. Over the past 50 years, the incidence of dengue disease has increased dramatically and the vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f647d43f189ee738eed2a608693aa896
https://europepmc.org/articles/PMC3623359/
https://europepmc.org/articles/PMC3623359/
