FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence

Autor: Krejci, Pavel, Prochazkova, Jirina, Smutny, Jiri, Chlebova, Katarina, Lin, Patricia, Aklian, Anie, Bryja, Vitezslav, Kozubik, Alois, Wilcox, William R.

Publikováno v: In Bone 2010 47(1):102-110

Receptor Tyrosine Kinases Activate Canonical WNT/?-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct Beta-Catenin Phosphorylation

Autor: Krejci, Pavel, Aklian, Anie, Kaucka, Marketa, Sevcikova, Eva, Prochazkova, Jirina, Masek, Jan Kukla, Mikolka, Pavol, Pospisilova, Tereza, Spoustova, Tereza, Weis, MaryAnn, Paznekas, William A., Wolf, Joshua H., Gutkind, J. Silvio, Wilcox, William R., Kozubik, Alois, Jabs, Ethylin Wang, Bryja, Vitezslav, Salazar, Lisa, Vesela, Iva, Balek, Lukas

Publikováno v: Krejci, Pavel; Aklian, Anie; Kaucka, Marketa; Sevcikova, Eva; Prochazkova, Jirina; Masek, Jan Kukla; et al.(2012). Receptor Tyrosine Kinases Activate Canonical WNT/?-Catenin Signaling via MAP Kinase/LRP6 Pathway and Direct Beta-Catenin Phosphorylation. PLoS ONE, 7(4), e35826. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8179m9f3

Receptor tyrosine kinase signaling cooperates with WNT/β-catenin signaling in regulating many biological processes, but the mechanisms of their interaction remain poorly defined. We describe a potent activation of WNT/β-catenin by FGFR2, FGFR3, EGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::48c240999655d92c52f0739e203fc9ac
http://www.escholarship.org/uc/item/8179m9f3

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.