Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Akkina Ramesh"'
Autor:
Wright Edwina, Solomon Ajantha, Akkina Ramesh, Lal Luxshimi, Evans Vanessa A, Lewin Sharon R, Cameron Paul U
Publikováno v:
Retrovirology, Vol 8, Iss 1, p 43 (2011)
Abstract Background HIV-1 infection of the thymus contributes to the defective regeneration and loss of CD4+ T cells in HIV-1-infected individuals. As thymic dendritic cells (DC) are permissive to infection by HIV-1, we examined the ability of thymic
Externí odkaz:
https://doaj.org/article/4edf4ba10cef44669e170db05e961dc6
Autor:
Akkina Ramesh, Tamhane Mayur
Publikováno v:
AIDS Research and Therapy, Vol 5, Iss 1, p 16 (2008)
Abstract Background Thus far gene therapy strategies for HIV/AIDS have used either conventional retroviral vectors or lentiviral vectors for gene transfer. Although highly efficient, their use poses a certain degree of risk in terms of viral mediated
Externí odkaz:
https://doaj.org/article/05f4de72c7b148fa9332c243d351ff1f
Autor:
Bandi Sriram, Akkina Ramesh
Publikováno v:
AIDS Research and Therapy, Vol 5, Iss 1, p 1 (2008)
Abstract Background Human embryonic stem (hES) cells hold considerable promise for cell replacement and gene therapies. Their remarkable properties of pluripotency, self-renewal, and tractability for genetic modification potentially allows for the pr
Externí odkaz:
https://doaj.org/article/4470c304cf9d4302afae8e4934b2c768
Publikováno v:
Retrovirology, Vol 3, Iss 1, p 76 (2006)
Abstract Background The currently well-established humanized mouse models, namely the hu-PBL-SCID and SCID-hu systems played an important role in HIV pathogenesis studies. However, despite many notable successes, several limitations still exist. They
Externí odkaz:
https://doaj.org/article/c442bffbda5b4fd4b48c3d9194e0d41a
Publikováno v:
Retrovirology, Vol 3, Iss 1, p 24 (2006)
Abstract Background Many novel studies and therapies are possible with the use of human embryonic stem cells (hES cells) and their differentiated cell progeny. The hES cell derived CD34 hematopoietic stem cells can be potentially used for many gene t
Externí odkaz:
https://doaj.org/article/e6419badb2064d6e9779efee40626df0
Autor:
Akkina Ramesh, Anderson Joseph
Publikováno v:
Retrovirology, Vol 2, Iss 1, p 53 (2005)
Abstract Background Stable simultaneous knock down of the HIV-1 coreceptors CCR5 and CXCR4 is a promising strategy to protect cells from both R5 macrophage tropic and X4 T cell tropic as well as dual tropic viral infections. The potency of shRNAs in
Externí odkaz:
https://doaj.org/article/d72f09a5d7fb43ecaa3867ec1b8b8a87
Autor:
Akkina Ramesh, Anderson Joseph
Publikováno v:
AIDS Research and Therapy, Vol 2, Iss 1, p 1 (2005)
Abstract Background RNA interference (RNAi) mediated by small interfering RNAs (siRNAs) has proved to be a highly effective gene silencing mechanism with great potential for HIV/AIDS gene therapy. Previous work with siRNAs against cellular coreceptor
Externí odkaz:
https://doaj.org/article/4e1d1c61cf6f47bb911f0dacdb26a49c
Publikováno v:
AIDS Research and Therapy, Vol 1, Iss 1, p 2 (2004)
Abstract Background RNA based antiviral approaches against HIV-1 are among the most promising for long-term gene therapy. These include ribozymes, aptamers (decoys), and small interfering RNAs (siRNAs). Lentiviral vectors are ideal for transduction o
Externí odkaz:
https://doaj.org/article/35dfdf7c8cda46ba849c886942756540
Publikováno v:
Frontiers in Immunology; 2024, p1-8, 8p
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