Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Akkaladevi Venkatesham"'
Autor:
Akkaladevi Venkatesham, Dhuldeo Kachare, Guy Schepers, Jef Rozenski, Mathy Froeyen, Arthur Van Aerschot
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 4020-4041 (2015)
In further study of our series of six-membered ring-containing nucleic acids, different 1',3'-di-O-methyl altropyranoside nucleoside analogs (DMANA) were synthesized comprising all four base moieties, adenine, cytosine, uracil and guanine. Following
Externí odkaz:
https://doaj.org/article/a3fe33227a894b2387addbb981237870
Autor:
Akkaladevi Venkatesham, Sambasiva Rao Pillalamarri, Flore De Wit, Eveline Lescrinier, Zeger Debyser, Arthur Van Aerschot
Publikováno v:
Molecules, Vol 24, Iss 3, p 468 (2019)
In vivo imaging of biological processes is an important asset of modern cell biology. Selectively reacting fluorophores herein are an important tool and click chemistry reactions take a large share in these events. 5-Ethynyl-2′-deoxyuridine (EdU) i
Externí odkaz:
https://doaj.org/article/01eaf417dd954d55a654ea4902bf3754
Autor:
Guy Van den Mooter, Akkaladevi Venkatesham, Arthur Van Aerschot, Tu Van Duong, Peter Adriaensens, Jan Van Humbeeck, Gunter Reekmans
Publikováno v:
Molecular Pharmaceutics. 14:1726-1741
We recently found that indomethacin (IMC) can polyethylene glycol 6000 (PEG) despite the fact that the effectively act as a powerful crystallization inhibitor for absence of interactions between the drug and the carrier in the solid state was reporte
Autor:
Alba Sebastián-Martín, Arthur Van Aerschot, Flore De Wit, Sambasiva Rao Pillalamarri, Zeger Debyser, Akkaladevi Venkatesham
Publikováno v:
J Biol Chem
Only a small portion of human immunodeficiency virus type 1 (HIV-1) particles entering the host cell results in productive infection, emphasizing the importance of identifying the functional virus population. Because integration of viral DNA (vDNA) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d393a3c9b2992570c01d98241078aba7
https://lirias.kuleuven.be/handle/123456789/639964
https://lirias.kuleuven.be/handle/123456789/639964
Publikováno v:
Helvetica Chimica Acta. 98:417-426
New pyrano[2′,3′: 5,6]chromeno[4,3-b]quinolin-4-ones have been synthesized by intramolecular aza-DielsAlder reaction of the azadienes generated in situ from aryl amines and 8-formyl-7-(prop-2-ynyl)2,3-disubstituted chromones using CuFe2O4 nanopar
Autor:
Paul Cos, Akkaladevi Venkatesham, Bharat Gadakh, Jenny Pouyez, Arthur Van Aerschot, Johan Wouters
Publikováno v:
Bioorganic and medicinal chemistry letters
The antibiotic fosmidomycin (3a) is an inhibitor of the non-mevalonate pathway for isoprenoid biosynthesis. Four analogues in which an acylated sulfonamide group is substituting for its phosphonate moiety have been synthesized in a fruitless effort t
Autor:
Suzanne J.F. Kaptein, Jef Rozenski, Johan Neyts, Mathy Froeyen, Arthur Van Aerschot, Milind Saudi, Akkaladevi Venkatesham
Publikováno v:
European journal of medicinal chemistry. 126
Previous efforts led to dicarboxamide derivatives like 1.3, comprising either an imidazole, pyrazine or fenyl ring as the central scaffold, with many congeners displaying strong inhibitory effects against dengue virus (DENV) in cell-based assays. Fol
Autor:
Akkaladevi Venkatesham, Kommu Nagaiah
Publikováno v:
Tetrahedron: Asymmetry. 23:1186-1197
The highly stereoselective synthesis of a biologically active stagonolide-C has been described. The pivotal functionalities are derived from Barbier allylation, an epoxidation by m -CPBA, a chiral-auxiliary mediated acetate aldol addition, a 1,3- ant
Publikováno v:
Tetrahedron: Asymmetry. 23:381-387
The stereoselective synthesis towards biologically active verbalactone and (+)-(3 R ,5 R )-3-hydroxy-5-decanolide has been described. The key functionalities are derived from a chiral-auxiliary mediated acetate aldol addition, an oxa-Michael reaction
Autor:
Balasubramanian Sridhar, Shaik Jeelani Basha, Anthony Addlagatta, Akkaladevi Venkatesham, R. Srinivasa Rao, Venkateshwarlu Saddanapu, A. V. S. Sarma, Kommu Nagaiah, Jhillu S. Yadav
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3259-3264
New cis-fused tetrahydrochromeno[4,3-b]quinolines have been synthesized by intramolecular [4+2] imino-Diels-Alder reactions of 2-azadienes derived in situ from aromatic amines and 7-O-prenyl derivatives of 8-formyl-2,3-disubstituted chromenones in th