Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Akiyuki Ikedo"'
Publikováno v:
Bulletin of the Chemical Society of Japan. 87:544-549
Glaziovianin A and its O7-propargyl analogue are potent cytotoxic isoflavones. We found that the O7-propargyl analogue completely arrested cell-cycle progression. We have achieved the large-scale s...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29edff18376d781b1e2e9152fff4ed15
https://doi.org/10.1246/bcsj.20130342
https://doi.org/10.1246/bcsj.20130342
Autor:
Masatoshi Takagi, Yoko Nagumo, Naoko Imamoto, Ichiro Hayakawa, Akihito Yokosuka, Hideo Kigoshi, Yoshihiro Mimaki, Sayaka Kazami, Hiroyuki Osada, Takumi Chinen, Takeo Usui, Akiyuki Ikedo
Publikováno v:
ACS Chemical Biology. 8:884-889
Glaziovianin A, an isoflavone isolated from the leaves of Ateleia glazioviana, inhibits the cell cycle progression in M-phase with an abnormal spindle structure, but its inhibitory mechanism has not been revealed. Here, we report that glaziovianin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b362f68a1b246d3c917465f2d34d47
https://doi.org/10.1021/cb300641h
https://doi.org/10.1021/cb300641h
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:5402-5404
Various derivatives of glaziovianin A, an antitumor isoflavone, were synthesized, and the cytotoxicity of each against HeLa S3 cells was investigated. Compared to glaziovianin A, the O7-allyl derivative was found to be more cytotoxic against HeLa S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5650e4eceda622bc45e00039f6287279
https://doi.org/10.1016/j.bmcl.2010.07.111
https://doi.org/10.1016/j.bmcl.2010.07.111
Publikováno v:
Bioorganicmedicinal chemistry. 20(19)
Various analogues of glaziovianin A, an antitumor isoflavone, were synthesized, and their biological activities were evaluated. O 7 -modified glaziovianin A showed strong cytotoxicity against HeLa S 3 cells. Compared to glaziovianin A, the O 7 -benzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f670c37347f03dc47b65a97ff3c7b16b
https://pubmed.ncbi.nlm.nih.gov/22921744
https://pubmed.ncbi.nlm.nih.gov/22921744
Publikováno v:
ChemInform. 39
Glaziovianin A (1) is a novel isoflavone derivative isolated from the leaves of the Brazilian tree Astelia glazioviana. Glaziovianin A (1) showed cytotoxic activity and was suggested to be an inhib...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::099062feab0952898c15442edf1688d6
https://doi.org/10.1002/chin.200814227
https://doi.org/10.1002/chin.200814227